Antioxidant polyphenols from fruits of the Myrtle family

来自桃金娘科水果的抗氧化多酚

• 批准号: 6656315
• 负责人: Kurt Allerslev Reynertson
• 金额: $ 3.09万
• 依托单位: HERBERT H. LEHMAN COLLEGE
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-09-17 至 2006-09-16
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6656315
• 关键词: alternative medicine; angiosperms; antioxidants; drug discovery /isolation; flavonoids; food processing /preparation; fruit; medicinal plants; plant extracts; predoctoral investigator

Many species of the Myrtle family (Myrtaceae) are popular edibles throughout the tropical and subtropical world. In addition, some are used medicinally in divergent traditional practices from South America to Southeast Asia. The fruits of two species of Eugenia (Myrtaceae) have shown a strong antioxidant activity in the 1,1-diphenyl-2- picrylhydrazyl (DPPH) assay, and subsequent ethnomedical and chemotaxonomic study of related plants in the subtribe Eugeniinae have led to the hypothesis that these fruits contain flavonoids or other polyphenolic compounds that exhibit an oxidative protection to biomolecules in humans. The fruits of ten popular edible species from this taxa will be analyzed for antioxidant activity using the DPPH assay. The most active extracts will be studied in greater detail to isolate and identify specific polyphenolic antioxidant phytochemicals. It is expected that novel antioxidant compounds will be discovered, and their chemical structures will be fully elucidated. This research will then use the analytical tools developed to look closely at beverages and vinegar made from the most active fruit to ascertain whether the beneficial phytochemicals in the fruit can be detected in commercial products.

默特尔家族（Myrtaceae）的许多物种在整个热带和亚热带世界中都是流行的食物。此外，从南美到东南亚的不同传统做法中，有些是在药物中使用的。两种尤金（Myrtaceae）的果实表明，在1,1-二苯基-2-丙烯酰羟基羟基苯基（DPPH）测定中具有很强的抗氧化活性，随后在eugtribe eugtribe eugeeniinae的相关植物中对相关植物进行了种族理学和化学学术研究表现出了强烈的抗氧化活性。这些水果含有类黄酮或其他多酚化合物，这些化合物对人类的生物分子具有氧化保护。使用DPPH分析，将分析该分类单元中十种流行的可食用物种的果实的抗氧化活性。将对最活跃的提取物进行更详细的研究，以隔离和鉴定特定的多酚抗氧化剂植物化学物质。预计将发现新型的抗氧化剂化合物，并将其化学结构完全阐明。然后，这项研究将使用开发的分析工具来仔细观察由最活跃的水果制成的饮料和醋，以确定在商业产品中是否可以检测到水果中有益的植物化学物质。