Antioxidant polyphenols from fruits of the Myrtle family

来自桃金娘科水果的抗氧化多酚

• 批准号: 6405800
• 负责人: Kurt Allerslev Reynertson
• 金额: $ 2.83万
• 依托单位: HERBERT H. LEHMAN COLLEGE
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-09-17 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/6405800
• 关键词: alternative medicine; angiosperms; antioxidants; drug discovery /isolation; flavonoids; food processing /preparation; fruit; medicinal plants; plant extracts; predoctoral investigator

Many species of the Myrtle family (Myrtaceae) are popular edibles throughout the tropical and subtropical world. In addition, some are used medicinally in divergent traditional practices from South America to Southeast Asia. The fruits of two species of Eugenia (Myrtaceae) have shown a strong antioxidant activity in the 1,1-diphenyl-2- picrylhydrazyl (DPPH) assay, and subsequent ethnomedical and chemotaxonomic study of related plants in the subtribe Eugeniinae have led to the hypothesis that these fruits contain flavonoids or other polyphenolic compounds that exhibit an oxidative protection to biomolecules in humans. The fruits of ten popular edible species from this taxa will be analyzed for antioxidant activity using the DPPH assay. The most active extracts will be studied in greater detail to isolate and identify specific polyphenolic antioxidant phytochemicals. It is expected that novel antioxidant compounds will be discovered, and their chemical structures will be fully elucidated. This research will then use the analytical tools developed to look closely at beverages and vinegar made from the most active fruit to ascertain whether the beneficial phytochemicals in the fruit can be detected in commercial products.

桃金娘科（桃金娘科）的许多物种是整个热带和亚热带世界的流行食品。此外，从南美洲到东南亚，有些在不同的传统做法中被用作药用。两种桉树（桃金娘科）的果实在 1,1-二苯基-2-苦基肼 (DPPH) 测定中显示出很强的抗氧化活性，随后对桉树亚科相关植物进行的民族医学和化学分类学研究得出了这一假设这些水果含有类黄酮或其他多酚化合物，对人体生物分子具有氧化保护作用。将使用 DPPH 测定来分析该类群中十种流行食用物种的果实的抗氧化活性。将更详细地研究最具活性的提取物，以分离和鉴定特定的多酚抗氧化植物化学物质。预计将会发现新的抗氧化剂化合物，并且它们的化学结构将被充分阐明。然后，这项研究将使用开发的分析工具仔细观察由最活跃的水果制成的饮料和醋，以确定是否可以在商业产品中检测到水果中的有益植物化学物质。