Simian Virus 40 (SV40)

猿猴病毒 40 (SV40)

• 批准号: 6556299
• 负责人: Eric A Engels
• 金额: --
• 依托单位: DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/6556299
• 关键词: drug related neoplasm /cancer; environmental contamination; poliomyelitis vaccine; simian virus 40

Simian virus 40 (SV40) is a monkey poliomavirus that was a contaminant of vaccines produced in the 1950s and early 1960s, including the inactivated polio vaccine, which was given to millions of people. SV40 causes cancer in laboratory animals, and more controversially, SV40 DNA has been detected in some human tumors. Nonetheless, it is not known whether SV40 causes human cancer. These studies look at the association between SV40 and human cancer.

猿猴病毒 40 (SV40) 是一种猴脊髓灰质炎病毒，是 20 世纪 50 年代和 1960 年代初生产的疫苗的污染物，其中包括为数百万人接种的灭活脊髓灰质炎疫苗。 SV40 会导致实验动物患癌症，更有争议的是，在一些人类肿瘤中也检测到了 SV40 DNA。尽管如此，尚不清楚 SV40 是否会导致人类癌症。这些研究着眼于 SV40 与人类癌症之间的关联。