CORE--CYTOGENETICS

核心--细胞遗传学

• 批准号: 6652724
• 负责人: ROBERT B. JENKINS
• 金额: $ 7.23万
• 依托单位: MAYO CLINIC ROCHESTER
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-08-28 至 2003-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6652724
• 关键词: biomedical facility; cytogenetics; neoplasm /cancer; neoplasm /cancer genetics; oncology

With the recognition that cancer is a genetic disease, many cancer researchers, including scientists in the Mayo Clinic Cancer Center (MCCC), require access to routine and advanced cytogenetics services. Such services can aid in the identification of genetic regions important for the development of specific malignancies. Such services can also be used to characterize the clonality of tumor specimens and determine the origin (e.g., mouse vs. human) of a specific tumor culture. Thus, the Cytogenetics Shared Resource will provide cytogenetic and molecular cytogenetic services to MCCC members. In addition, this Shared Resource will prepare EBV-transformed B-lymphocyte cell lines for MCCC members.

随着人们认识到癌症是一种遗传性疾病，许多癌症研究人员，包括梅奥诊所癌症中心 (MCCC) 的科学家，需要获得常规和先进的细胞遗传学服务。 此类服务可以帮助识别对特定恶性肿瘤的发展重要的遗传区域。 此类服务还可用于表征肿瘤样本的克隆性并确定特定肿瘤培养物的起源（例如小鼠与人类）。因此，细胞遗传学共享资源将为 MCCC 会员提供细胞遗传学和分子细胞遗传学服务。 此外，该共享资源将为 MCCC 会员准备 EBV 转化的 B 淋巴细胞系。