BIACORE 3000 Biosensor

BIACORE 3000 生物传感器

• 批准号: 6440970
• 负责人: WILLIAM H KANE
• 金额: $ 27万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-04-01 至 2003-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6440970
• 关键词: biomedical equipment purchase; biosensor device

DESCRIPTION (provided by the applicant): This is a application from a diverse group of six investigators within the Departments of Medicine, Immunology, Pharmacology and Cancer Biology to purchase a BIAcore 3000 biosensor to support 10 ongoing NIH funded research projects in the areas of immunology, blood proteins and signal transduction. Duke University currently has three state-of-the-art biosensors, one BIAcore 2000 and two BIAcore 3000 instruments which are available to the proposed user group on only a limited basis. One older BIAcore 1000 biosensor and one IASys biosensor are available, however, these instruments lack the sensitivity and throughput required for performing the applications of the group of investigators which will require greater than 95 percent of the total usage of the instrument. Access to the instrument will be made available to other users based upon the advice of an internal advisory committee. The instrument will be integrated into the core facilities of the Duke Human Immunology Core Facility and the Duke Specialized Center of Research (SCOR) in Rheumatoid Arthritis. Continued financial support for the operation and maintenance of the instrument will be provided by a charge back mechanism with additional support from the Department of Medicine. A highly skilled investigator has been specifically recruited to Duke University by the Department of Medicine to supervise the day-to-day operations of the instrument. The Department of Medicine will also provide the salary support for a technician who will be the dedicated operator of the instrument. In summary, this group of investigators has a demonstrated need and is requesting support for state-of-the-art BIAcore 3000 biosensor. Advisory committees, institutional support, financial support for continued maintenance and management plans are in place to insure that the instrument will be fully and appropriately utilized.

描述（由申请人提供）：这是一份来自不同领域的申请 医学、免疫学系的六名研究人员组成的小组， 药理学和癌症生物学购买 BIAcore 3000 生物传感器来支持 10 个正在进行的 NIH 资助的免疫学、血液领域的研究项目 蛋白质和信号转导。杜克大学目前拥有三所 最先进的生物传感器，一台 BIAcore 2000 和两台 BIAcore 3000 仪器 仅在有限的基础上向提议的用户组提供。一 不过，可以使用较旧的 BIAcore 1000 生物传感器和一个 IASys 生物传感器， 这些仪器缺乏执行所需的灵敏度和吞吐量 调查组的申请需要大于 仪器总使用量的 95%。访问仪器将 根据内部咨询的建议提供给其他用户 委员会。该仪器将集成到该中心的核心设施中 杜克大学人类免疫学核心设施和杜克大学专业研究中心 (SCOR) 治疗类风湿性关节炎。持续为运营提供财务支持 仪器的维护将由退款机制提供 并得到医学系的额外支持。一个高技能的 调查员已被专门招募到杜克大学 医学部负责监督医院的日常运作 乐器。医学部还将提供薪资支持 一名技术人员将担任仪器的专门操作员。总之， 这组调查人员有明确的需求并请求支持 适用于最先进的 BIAcore 3000 生物传感器。机构咨询委员会 支持，对持续维护和管理计划的财政支持 到位，以确保该文书将充分、适当地 被利用。