Risk Factors for Antisocial Behavior

反社会行为的危险因素

• 批准号: 6679130
• 负责人: Laura A Baker
• 金额: $ 2.33万
• 依托单位: UNIVERSITY OF SOUTHERN CALIFORNIA
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-01-05 至 2004-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6679130
• 关键词: Risk; Factors; Antisocial; Behavior

DESCRIPTION (provided by applicant): Emotion-related processes play an important role in the development of aggression and antisocial behavior. What is not known is the extent to which these emotion-related processes or their relationship to antisocial behavior may be genetically or environmentally based. We propose to investigate the genetic and environmental bases of psychophysiological and behavior indicators of emotion processing and responding, and their relationships to aggression and antisocial behavior in an ongoing study oft-wins (age 9-10 years). As part of this NIMH-funded investigation (Risk Factors for Antisocial Behavior; MH 58354), we have implemented a psychophysiological and behavioral assessment protocol for understanding emotion-related variables in the development of antisocial behavior and aggression. These involve teacher ratings of children's emotion regulation and outcomes (emotionality and lability), as well as a comprehensive psychophysiological assessment of emotional processing and responding: autonomic nervous system (ANS) measures (both electrodermal and cardiovascular recordings, including vagal tone), electrocortical (EEG and ERP) measures, and electromyographic (ECG) measures of startle potentiation. Additional tasks have been included in the psychophysiological protocol in order to measure emotional processing (fear and sadness) during film clips, startle modulation to emotionally laden stimuli (faces), anticipatory fear (using a countdown procedure), and responses to embarrassing questions. We have also added two tasks that tap less voluntary attentionat processes-auditory sensory gating (during a P50 gating task), and auditory sensory discrimination (during a mismatch negativity task). With this comprehensive assessment we are in a position to investigate the genetic and environmental basis of emotional-related processes and their relationships to antisocial behavior in children on the brink of adolescence. These variables will continue to be of considerable significance during planned follow-up assessments, enabling differentiation among several antisocial pathways, including those leading to violence and substance use. Supplemental funding is requested to continue with data collection, processing, and analysis of this expanded assessment of emotion-related processes and outcomes. These new data will provide a tremendous opportunity to investigate the genetic and environmental bases of emotional responding and its relationship to antisocial behavior. These findings will provide a better understanding of the roots of human aggression, which may ultimately lead to more effective avenues for treatment and prevention of this important social problem.

描述（由申请人提供）：与情绪相关的过程在侵略和反社会行为的发展中起着重要作用。尚不清楚的是这些与情绪相关的过程或它们与反社会行为的关系的程度可能是基于遗传或环境的。我们建议研究情绪处理和反应的心理生理学和行为指标的遗传和环境基础，以及它们与正在进行的研究中的侵略和反社会行为的关系（9-10岁）。 作为NIMH资助的研究的一部分（反社会行为的风险因素； MH 58354），我们实施了一种心理生理和行为评估方案，用于理解反社会行为和侵略性的情绪相关变量。这些涉及教师对儿童情绪调节和结果（情绪和不稳定）的评分，以及对情绪处理和反应的全面心理生理评估：自主神经系统（ANS）措施（ANS）措施（电性膜和心血管疾病记录，包括模糊的音调），电皮质态（EEG和EEG和ERP），启动（EEG和ERP）措施（ECG）。心理生理方案中已包含其他任务，以衡量胶片片段期间的情绪处理（恐惧和悲伤），对情感上充满刺激的惊吓调制（面孔），预期的恐惧（使用倒计时程序）以及对令人尴尬的问题的回答。我们还添加了两项任务，这些任务次数较少自愿注意过程 - 声音门控（在P50门控任务期间）和听觉感觉歧视（在不匹配的负效率任务中）。 通过这种全面的评估，我们可以研究与情绪相关过程的遗传和环境基础，及其与青春期边缘儿童的反社会行为的关系。在计划的随访评估期间，这些变量将继续具有很大的意义，从而使几种反社会途径之间的分化，包括导致暴力和药物使用的途径。要求补充资金继续进行数据收集，处理和分析对情绪相关过程和结果的扩展评估。这些新数据将为研究情绪反应的遗传和环境基础提供巨大的机会及其与反社会行为的关系。这些发现将更好地了解人类侵略的根源，这最终可能导致更有效的治疗和预防这一重要社会问题的途径。