HEALTHY WEIGHT MANAGEMENT FOR BREAST CANCER SURVIVORS

乳腺癌幸存者的健康体重管理

• 批准号: 6417972
• 负责人: CHERYL L ROCK
• 金额: $ 12.17万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-04-26 至 2004-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6417972
• 关键词: behavioral /social science research tag; breast neoplasms; clinical trials; cognitive behavior therapy; dietary control; disease /disorder proneness /risk; exercise; female; group counseling; health services research tag; human subject; human therapy evaluation; nutrition related tag; obesity; patient oriented research; questionnaires; telemedicine; weight control; women's health

Weight gain commonly occurs in women following the diagnosis of breast cancer. Post-diagnosis weight gain may increase risk for recurrence, and obesity at diagnosis of breast cancer is an established negative prognostic factor. Weight control is of great concern to many breast cancer survivors. Post-diagnosis weight gain is positively associated with energy intake and inversely related to physical activity level, suggest that behavioral strategies to reduce energy intake or increase exercise are likely to influence the long-term pattern of weight gain. Newer behavioral skills training programs to promote the adoption and maintenance of physical activity based on social learning theory have demonstrated success in other groups of inactive adults. Also, we have demonstrated than an intensive, innovative telephone-based counseling intervention can promote major changes in the dietary intakes for women at risk for breast cancer recurrence. The hypothesis to be tested in this exploratory project is that telephone-based counseling can also be useful in facilitating the adoption and maintenance of increased physical activity, and thus, promote weight loss in overweight and obese breast cancer survivors. One approach to healthy weight management emphasizes increased physical activity, improved body image, self- acceptance, and healthy eating attitudes and behaviors. The core content of the curriculum to be used in this project is based on a behavioral skills training program that has been shown to be effective in other target groups of inactive adults, with the incorporation of cognitive-behavioral techniques and emotional processing to promote acceptance and address the unique needs and characteristics of breast cancer survivors. The specific aims of this study are: (1) To examine the effect of a group- based program to increase physical activity and promote healthy eating attitudes and behaviors on measured weight change at the end of an intensive treatment period (16 weeks) and at one year, compared to a wait-list control group; (2) To examine the additional effect of individualized telephone counseling to increase physical activity and promote healthy eating attitudes and behaviors on measured weight change at the end of an intensive treatment period (16 weeks) and at one year, compared to the control group; and (3) To collect preliminary data on the change in level of physical activity that may be expected to occur in breast cancer survivors who participate in a group-based program and individualized telephone counseling to promote healthy weight management.

诊断为乳腺癌后，女性通常会增加体重。诊断后体重增加可能会增加复发的风险，而诊断乳腺癌的肥胖症是既定的负预后因素。对于许多乳腺癌幸存者来说，体重控制非常关注。诊断后体重增加与能量摄入呈正相关，并且与体育活动水平成反比，这表明减少能量摄入或增加运动的行为策略可能会影响体重增加的长期模式。基于社会学习理论的促进和维持体育锻炼的采用和维持的新型行为技能培训计划在其他不活跃成年人群体中取得了成功。此外，我们已经证明了超过一个基于电话的咨询干预措施的强化，可以促进患有乳腺癌复发风险的女性饮食摄入量的重大变化。在这个探索性项目中要检验的假设是，基于电话的咨询也可用于促进和维持增加的体育锻炼，从而促进超重和肥胖的乳腺癌幸存者的体重减轻。健康体重管理的一种方法强调了增加的体育锻炼，改善身体形象，自我接受以及健康的饮食态度和行为。该项目中使用的课程的核心内容是基于行为技能培训计划，该计划已被证明在其他非活动成年人的目标群体中有效，并结合了认知行为的技术和情感处理，以促进接受并解决乳腺癌幸存者的独特需求和特征。这项研究的具体目的是：（1）研究基于小组计划的效果，以增加体育锻炼，并在强化治疗期结束时（16周）和一年，与候补名单对照组相比，对测量体重变化的健康饮食态度和行为； （2）检查个性化电话咨询的额外效果，以增加体育锻炼，并在强化治疗期结束时（16周）（16周）和一年，与对照组相比，对测量的体重变化进行了健康饮食态度和行为； （3）收集有关体育锻炼水平变化的初步数据，这些数据可能会在乳腺癌幸存者中发生，这些乳腺癌幸存者参加了基于小组的计划和个性化的电话咨询，以促进健康的体重管理。