UCSD Biorepository Shared Resource

加州大学圣地亚哥分校生物样本库共享资源

• 批准号: 8072507
• 负责人: CHERYL L ROCK
• 金额: $ 16.18万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-07-07 至 2016-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8072507
• 关键词: Address; Aliquot; Area; Behavioral Genetics; Bioinformatics; Biological; Biological Assay; Biometry; Blood; Categories; Characteristics; Clinical; Collection; Computers; Data; Databases; Ensure; Epidemiology; Equipment; Faculty; Future; Human Resources; Inflammation; Insulin Resistance; Knowledge; Laboratories; Link; Malignant Neoplasms; Methods; Monitor; Nutritional; Obesity; Participant; Plasma; Procedures; Process; Quality Control; RNA; Research; Research Project Grants; Resource Sharing; Risk; Sampling; Services; Source; Specimen; Staging; System; T-Cell Receptor-Rearrangement Excision DNA Circles; Training; Urine; base; biobank; diet and exercise; energy balance; instrumentation; malignant breast neoplasm; operation; sample collection

ABSTRACT The specific aims of the Biorepository Shared Resource are (1) to facilitate the TREC Center research projects by providing expertise and centralized service in the collection, processing, analysis and management of biological samples, and (2) to serve as a source of biological samples for ancillary and future studies during and beyond the TREC Center operation, because biological samples may be made available for use in research as new knowledge in this area evolves. The core faculty and staff also will provide expert guidance into final selection of assays and laboratories for TREC Center project biological sample analysis, ensuring that analytical laboratories are monitored for quality control (QC) data and activities. The core personnel, who have specialized training and expertise, will facilitate appropriate biological sample collection and processing methods, materials, and procedures to ensure that the data and results produced by TREC Center projects are of good quality to enable the aims to be optimally addressed. A key component ofthe Biorepository Shared Resource is a computer-based system to log and track all samples and aliquots, so that analyses of TREC Center projects are efficient and the likelihood of misplaced samples and missing data is minimized. Core personnel will use equipment and instrumentation that is high-quality, and well-maintained. Providing the materials and services necessary for biological sample collection and management through a centralized core will ensure quality and efficiency for the TREC Center research projects.

抽象的 生物样本库共享资源的具体目标是 (1) 通过在生物样本的收集、处理、分析和管理方面提供专业知识和集中服务来促进 TREC 中心的研究项目，以及 (2) 作为生物样本的来源用于 TREC 中心运营期间和之后的辅助和未来研究，因为生物样本可用于 随着该领域新知识的发展而进行的研究。核心教职员工还将为 TREC 中心项目生物样本分析的测定和实验室的最终选择提供专家指导，确保分析实验室的质量控制 (QC) 数据和活动受到监控。受过专门培训并具有专业知识的核心人员将促进适当的生物样本采集和处理 方法、材料和程序，以确保 TREC 中心项目产生的数据和结果具有良好的质量，从而能够最佳地实现目标。生物样本库共享资源的一个关键组成部分是一个基于计算机的系统，用于记录和跟踪所有样本和等分试样，从而使 TREC 中心项目的分析高效，并将样本放错位置和数据丢失的可能性降至最低。核 人员将使用高质量且维护良好的设备和仪器。通过集中核心提供生物样本采集和管理所需的材料和服务，将确保 TREC 中心研究项目的质量和效率。