MBAT A novel psychosocial cancer intervention

MBAT 一种新型心理社会癌症干预措施

• 批准号: 7277390
• 负责人: Daniel A Monti
• 金额: $ 7.8万
• 依托单位: THOMAS JEFFERSON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-09-01 至 2010-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7277390
• 关键词: alternative medicine; arts; behavioral /social science research tag; breast neoplasms; clinical research; clinical trials; cytokine; fatigue; female; group counseling; health services research tag; heart rate; human subject; human therapy evaluation; meditation; neoplasm /cancer immunology; nuclear factor kappa beta; outcomes research; patient oriented research; personality; psychological aspect of cancer; psychological stressor; psychological tests; quality of life; questionnaires; social support network

Cancer patients frequently report high levels of distress and unmet psychosocial needs, both of which can contribute to negative health outcomes. Addressing this problem with psychosocial group interventions has had documented success in several cancer populations. The proposed study is designed to test the efficacy of a recently developed, innovative, multi-modal group program for cancer patients, and to compare it to a standard cancer support group. The intervention, mindfulness-based art therapy (MBAT), was developed with the specific purpose of enhancing both the supportive and expressive aspects of the typically available group treatment. This study is intended to build upon the very encouraging results of a recently completed clinical trial (N=111) that demonstrated highly significant improvements in symptoms of psychological distress and quality of life in a heterogeneous group of cancer patients who received the MBAT intervention, as compared to a similar group who received no intervention. In the proposed study, 339 women will be enrolled (226 with breast cancer and 113 with other cancer diagnoses). The breast cancer patients will be randomized to either the MBAT experimental arm or a standardized breast cancer support group. The women with other cancer diagnoses will be consecutively assigned to the MBAT group. Groups will be compared on measures of psychological distress (SCL-90-R) and key aspects of health-related quality of life (SF-36, general health and mental health subscales). In addition, for the MBAT group, comparisons on these measures will be made between breast and non-breast cancer patients . Secondarily, we will consider treatment effects on autonomic nervous system and immune system functioning, fatigue, and traumatic stress, and examine the role of social support and personality factors. This study is a crucial step towards testing efficacy and assessing for potential advantages of MBAT over a standard support group format. Our long-range goal is to find innovative means of improving the psychosocial health of cancer survivors.

癌症患者经常报告高度痛苦和未得到满足的社会心理需求，这两者都会导致负面的健康结果。通过社会心理团体干预来解决这个问题已经在一些癌症人群中取得了成功。拟议的研究旨在测试最近开发的创新型多模式小组计划对癌症患者的功效，并将其与标准癌症支持小组进行比较。基于正念的艺术治疗（MBAT）干预措施的开发，其具体目的是增强通常可用的团体治疗的支持性和表达性方面。这项研究旨在建立在最近完成的一项临床试验 (N=111) 非常令人鼓舞的结果的基础上，该试验表明接受 MBAT 干预的一组异质癌症患者的心理困扰症状和生活质量得到了显着改善，如与未接受干预的类似组进行比较。在拟议的研究中，将招募 339 名女性（226 名患有乳腺癌，113 名患有其他癌症）。乳腺癌患者将被随机分配到 MBAT 实验组或标准化乳腺癌支持组。患有其他癌症诊断的女性将连续分配到 MBAT 组。将比较各组的心理困扰指标 (SCL-90-R) 和健康相关生活质量的关键方面 （SF-36，一般健康和心理健康分量表）。此外，对于MBAT组，还将在乳腺癌和非乳腺癌患者之间对这些措施进行比较。其次，我们将考虑治疗对自主神经系统和免疫系统功能、疲劳和创伤应激的影响，并检查社会支持和人格因素的作用。这项研究是测试功效和评估 MBAT 相对于标准支持小组形式的潜在优势的关键一步。我们的长期目标是找到改善癌症幸存者心理社会健康的创新方法。