MBAT A novel psychosocial cancer intervention

MBAT 一种新型心理社会癌症干预措施

• 批准号: 7117774
• 负责人: Daniel A Monti
• 金额: $ 40.92万
• 依托单位: THOMAS JEFFERSON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-09-01 至 2010-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7117774
• 关键词: alternative medicine; arts; behavioral /social science research tag; breast neoplasms; clinical research; clinical trials; cytokine; fatigue; female; group counseling; health services research tag; heart rate; human subject; human therapy evaluation; meditation; neoplasm /cancer immunology; nuclear factor kappa beta; outcomes research; patient oriented research; personality; psychological aspect of cancer; psychological stressor; psychological tests; quality of life; questionnaires; social support network

Cancer patients frequently report high levels of distress and unmet psychosocial needs, both of which can contribute to negative health outcomes. Addressing this problem with psychosocial group interventions has had documented success in several cancer populations. The proposed study is designed to test the efficacy of a recently developed, innovative, multi-modal group program for cancer patients, and to compare it to a standard cancer support group. The intervention, mindfulness-based art therapy (MBAT), was developed with the specific purpose of enhancing both the supportive and expressive aspects of the typically available group treatment. This study is intended to build upon the very encouraging results of a recently completed clinical trial (N=111) that demonstrated highly significant improvements in symptoms of psychological distress and quality of life in a heterogeneous group of cancer patients who received the MBAT intervention, as compared to a similar group who received no intervention. In the proposed study, 339 women will be enrolled (226 with breast cancer and 113 with other cancer diagnoses). The breast cancer patients will be randomized to either the MBAT experimental arm or a standardized breast cancer support group. The women with other cancer diagnoses will be consecutively assigned to the MBAT group. Groups will be compared on measures of psychological distress (SCL-90-R) and key aspects of health-related quality of life (SF-36, general health and mental health subscales). In addition, for the MBAT group, comparisons on these measures will be made between breast and non-breast cancer patients . Secondarily, we will consider treatment effects on autonomic nervous system and immune system functioning, fatigue, and traumatic stress, and examine the role of social support and personality factors. This study is a crucial step towards testing efficacy and assessing for potential advantages of MBAT over a standard support group format. Our long-range goal is to find innovative means of improving the psychosocial health of cancer survivors.

癌症患者经常报告高水平的困扰和未满足的社会心理需求，这两者都会导致负面的健康结果。通过社会心理群体干预解决这个问题已经证明了几个癌症人群的成功。拟议的研究旨在测试针对癌症患者的最近开发的，创新的多模式组计划的功效，并将其与标准癌症支持组进行比较。开发了基于正念的艺术疗法（MBAT）的干预措施，其特定目的是增强通常可用的组治疗的支持性和表达性方面。这项研究旨在基于最近完成的临床试验（n = 111）的令人鼓舞的结果，该试验表明，与未接受干预措施的类似组相比，在接受MBAT干预的异质癌症患者中，心理困扰和生活质量的症状得到了极大的显着改善。在拟议的研究中，将招募339名妇女（226例患有乳腺癌，有113名患有其他癌症诊断）。乳腺癌患者将被随机分为MBAT实验组或标准化的乳腺癌支持组。具有其他癌症诊断的妇女将连续分配给MBAT组。将根据心理困扰度量（SCL-90-R）和与健康相关的生活质量的关键方面进行比较 （SF-36，一般健康和心理健康子量表）。此外，对于MBAT组，将在乳腺癌和非胸腺癌患者之间进行这些措施的比较。其次，我们将考虑对自主神经系统和免疫系统功能，疲劳和创伤压力的治疗作用，并检查社会支持和人格因素的作用。这项研究是测试功效并评估MBAT与标准支持组格式的潜在优势的关键步骤。我们的远程目标是找到改善癌症幸存者心理健康的创新手段。