Conference--Molecular Biology in Orthopaedics

会议--骨科分子生物学

• 批准号: 6317647
• 负责人: RANDY N ROSIER
• 金额: $ 2.5万
• 依托单位: AMERICAN ACADEMY OF ORTHOPAEDIC SURGEONS
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-04-17 至 2002-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6317647
• 关键词: information dissemination; meeting /conference /symposium; molecular biology; musculoskeletal disorder; musculoskeletal system; orthopedics; travel

DESCRIPTION: The explosive progress and resulting technical advances in molecular biology during the past decade present an astonishing potential for translational approaches to understanding and treating diseases. For example, musculoskeletal disorders' enormous prevalence and societal costs underscore the value of the clinical application of advances in molecular biology to this field. This 3 day workshop co-sponsored by the American Academy of Orthopaedic Surgeons (AAOS) will be held September 7-9, 2001 in Scottsdale, AZ, and will bring together a diverse group of molecular biologists, orthopaedic clinicians, and young investigators with research interests in the molecular study of the musculoskeletal system to provide an overview of the relevant topics from a variety of perspectives and to define the most promising future directions for molecular biological research as applied to skeletal tissues and orthopaedic clinical problems. The proposed workshop goals include: 1. Defining the current status of basic, technical and clinical applications of molecular biology in orthopaedics. 2. Providing a cross-disciplinary discussion forum to generate novel molecular applications to orthopaedics 3. Introducing young orthopaedic investigators and clinicians to technologies that may enhance their research. 4. Defining needs and opportunities for basic and translational applications of molecular biology to orthopaedics. 5. Identifying future directions of molecular biologic research as it relates to the musculoskeletal system. 6. Maximizing impact of the workshop through publication of a book in conjunction with the AAOS summarizing the current basic, technical, and clinical knowledge of molecular biology and future related research directions in orthopaedics. The workshop will attempt to achieve these aims by instructional seminars focusing on new molecular techniques, genomics, and gene structure, and special topic sections on development, genetic diseases, musculoskeletal oncology, transgenic models, gene therapy, and regulation of gene expression. Participants will also discuss regulation of gene expression as it relates specifically to osteoblasts, osteoclasts, cartilage, stem cells, and injury and repair.

描述：爆炸性进度和最终的技术进步 在过去的十年中，分子生物学具有惊人的潜力 理解和治疗疾病的翻译方法。例如， 肌肉骨骼疾病的巨大流行和社会成本强调 分子生物学进步的临床应用的价值对此 场地。由美国骨科学会共同赞助的为期3天的研讨会 外科医生（AAOS）将于2001年9月7日至9日在亚利桑那州的斯科茨代尔举行，威尔 汇集一组各种分子生物学家，骨科临床医生， 以及在分子研究中具有研究兴趣的年轻研究者 肌肉骨骼系统，概述了 各种观点，并定义最有希望的未来方向 用于骨骼组织和骨科的分子生物学研究 临床问题。拟议的研讨会目标包括：1。定义当前 分子生物学基础，技术和临床应用的状态 骨科。 2。提供一个跨学科讨论论坛来生成 新型分子应用到骨科3。引入年轻的骨科 调查人员和临床医生可以研究可以增强其研究的技术。 4。定义需求和机会，用于基本和翻译的应用 分子生物学到骨科。 5。确定未来的方向 与肌肉骨骼系统有关的分子生物学研究。 6。 通过出版一本书的结合来最大化研讨会的影响 AAO总结了当前的基本，技术和临床知识 分子生物学和未来相关的骨科研究方向。 研讨会将尝试通过教学研讨会来实现这些目标 专注于新的分子技术，基因组学和基因结构以及特殊 关于发育，遗传疾病，肌肉骨骼肿瘤学的主题部分， 转基因模型，基因治疗和基因表达的调节。 参与者还将讨论基因表达的调节 特别针对成骨细胞，骨细胞，软骨，干细胞和损伤 维修。