UNIVERSITY OF WASHINGTON RESEARCH CORE CENTER

华盛顿大学研究核心中心

• 批准号: 6379591
• 负责人: Edwin W Rubel
• 金额: $ 70.39万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-09-25 至 2005-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6379591
• 关键词: biomedical facility; communication disorders

This is the University of Washington application for a Research Core Grant from the NIDCD. The NIDCD funded Research base is composed of 19 grants to 16 investigators supported by $33,515,491 annual direct costs. The Cores will also provide infrastructure support for 5 NIH funded investigators whose research is in research programs, and to stimulate new research initiatives. The Human Subject Recruitment Core will continue a long-standing infant subject pool that is essential for research on the development of hearing and language perception in human infants and babies. Also, databases will be developed on populations of subjects with specific hearing and perceptual impairments. The Computer Resources Core will provide personnel with skills needed for development of software for real-time physiological and behavioral investigations of auditory processing in animals and humans. In addition,, a system and network manager is to be hired to teach and advice investigators on the optimal computer solutions. The Imaging Core will provide personnel and equipment maintenance for programs making extensive use of modern digital microscopic imaging methods including confocal Microscopy, 3-dimensional reconstructions and quantitative analyses of cellular attributes. The Core will also support human brain imaging initiatives. The Mouse Genetics Core will control breeding and DNA screening for investigators using inbred and genetically manipulated mouse strains. Equipment will be provided for rapid analyses of DNA sequences to enhance the efficiency of studies using mouse models of communication disorders. The Research Cores will be supported by an Administrative Core to oversee the operations of each Research Core, organize group meetings, provide clerical, fiscal and personnel support, and prepare reports to funding agency.

这是华盛顿大学向 NIDCD 申请的研究核心补助金。 NIDCD 资助的研究基地由向 16 名研究人员提供的 19 项拨款组成，每年直接费用为 33,515,491 美元。核心还将为 5 名 NIH 资助的研究人员提供基础设施支持，他们的研究属于研究计划，并刺激新的研究计划。人类受试者招募核心将继续长期存在的婴儿受试者库，这对于研究人类婴儿和婴儿的听力和语言感知的发展至关重要。此外，还将针对具有特定听力和知觉障碍的受试者群体开发数据库。计算机资源核心将为人员提供开发软件所需的技能，以对动物和人类的听觉处理进行实时生理和行为研究。此外，还将聘请一名系统和网络经理来向调查人员教授最佳计算机解决方案并为其提供建议。成像核心将为广泛使用现代数字显微成像方法（包括共焦显微镜、3维重建和细胞属性定量分析）的项目提供人员和设备维护。该核心还将支持人脑成像计划。小鼠遗传学核心将为研究人员使用近交和基因操纵的小鼠品系控制育种和 DNA 筛选。将提供用于快速分析 DNA 序列的设备，以提高使用沟通障碍小鼠模型进行研究的效率。研究核心将得到行政核心的支持，负责监督每个研究核心的运作，组织小组会议，提供文书、财务和人事支持，并为资助机构准备报告。