UNIVERSITY OF WASHINGTON RESEARCH CORE CENTER

华盛顿大学研究核心中心

• 批准号: 6379591
• 负责人: Edwin W Rubel
• 金额: $ 70.39万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-09-25 至 2005-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6379591
• 关键词: biomedical facility; communication disorders

This is the University of Washington application for a Research Core Grant from the NIDCD. The NIDCD funded Research base is composed of 19 grants to 16 investigators supported by $33,515,491 annual direct costs. The Cores will also provide infrastructure support for 5 NIH funded investigators whose research is in research programs, and to stimulate new research initiatives. The Human Subject Recruitment Core will continue a long-standing infant subject pool that is essential for research on the development of hearing and language perception in human infants and babies. Also, databases will be developed on populations of subjects with specific hearing and perceptual impairments. The Computer Resources Core will provide personnel with skills needed for development of software for real-time physiological and behavioral investigations of auditory processing in animals and humans. In addition,, a system and network manager is to be hired to teach and advice investigators on the optimal computer solutions. The Imaging Core will provide personnel and equipment maintenance for programs making extensive use of modern digital microscopic imaging methods including confocal Microscopy, 3-dimensional reconstructions and quantitative analyses of cellular attributes. The Core will also support human brain imaging initiatives. The Mouse Genetics Core will control breeding and DNA screening for investigators using inbred and genetically manipulated mouse strains. Equipment will be provided for rapid analyses of DNA sequences to enhance the efficiency of studies using mouse models of communication disorders. The Research Cores will be supported by an Administrative Core to oversee the operations of each Research Core, organize group meetings, provide clerical, fiscal and personnel support, and prepare reports to funding agency.

这是华盛顿大学的NIDCD研究核心赠款的申请。 NIDCD资助的研究基础由16名调查人员组成，由16名调查人员组成，其中33,515,491美元的年度直接费用。核心还将为5名NIH资助的研究人员提供基础设施支持，他们的研究计划正在研究计划，并刺激新的研究计划。人类受试者招聘核心将继续一个长期存在的婴儿主题库，这对于研究人类和婴儿的听力和语言感知的研究至关重要。此外，还将针对具有特定听力和感知障碍的受试者人群开发数据库。计算机资源核心将为人员提供开发软件的技能，以实时对动物和人类的听觉处理进行实时生理和行为调查。此外，应聘请系统和网络经理来教授和建议调查人员有关最佳计算机解决方案。成像核心将提供人员和设备维护，以广泛使用现代数字微观成像方法，包括共聚焦显微镜，三维重建和细胞属性的定量分析。核心还将支持人脑成像计划。小鼠遗传学核心将使用近交和遗传操纵的小鼠菌株来控制研究人员的繁殖和DNA筛查。将提供设备以快速分析DNA序列，以使用沟通障碍的小鼠模型来提高研究的效率。研究核心将得到行政核心的支持，以监督每个研究核心的运作，组织小组会议，提供文书，财政和人员支持，并向资助机构准备报告。