Unlocking the secret chemistry of organosulfur biodegradation

解开有机硫生物降解的秘密化学

• 批准号: DP240100126
• 负责人: Prof Spencer Williams
• 金额: $ 42.51万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2024
• 资助国家: 澳大利亚
• 起止时间: 2024-01-01 至 2027-12-31
• 项目状态: 未结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP240100126
• 关键词: Unlocking; secret; chemistry; organosulfur; biodegradation

The element sulfur is essential for life. Its transformation between organic-sulfur compounds to inorganic forms is a crucial part of the biogeochemical cycle. This project will elucidate the molecular details of the final leg of the biosulfur cycle: organosulfur breakdown into mineral form. An integrated chemical and biochemical approach will be used to illuminate how the carbon-sulfur bond is broken. This project will deliver a detailed molecular understanding of organosulfur breakdown to permit organosulfur recycling. Benefits of this research include potential biotechnology applications for breaking down xenobiotic organosulfonates and sustainable approaches to reduce dependence on agricultural fertilisers.

元素硫对生命至关重要。它在有机硫化合物对无机形式之间的转化是生物地球化学循环的关键部分。该项目将阐明生物硫周期的最后一条腿的分子细节：有机硫化成矿物形式。一种集成的化学和生化方法将用于阐明碳硫键如何破裂。该项目将对有机硫的崩溃提供详细的分子理解，以允许有机硫硫磺回收。这项研究的好处包括潜在的生物技术应用，以分解异生物生物有机磺酸盐和可持续方法，以减少对农业肥料的依赖。