TRAUMATIC GRIEF TREATMENT--A RANDOMIZED CONTROLLED STUDY

创伤性悲伤治疗——一项随机对照研究

• 批准号: 6193773
• 负责人: M Katherine Shear
• 金额: $ 36.25万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-08-15 至 2005-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6193773
• 关键词: anxiety; behavioral /social science research tag; clinical research; clinical trials; cognitive behavior therapy; depression; grief; human subject; human therapy evaluation; longitudinal human study; self concept; social support network

DESCRIPTION (Adapted from the Applicant's Abstract): This application requests funding for a 5 year study of a treatment for "traumatic grief." Over 16 million people are bereaved each year in the United States. For a substantial minority, grief is chronic, debilitating, and complicated by psychiatric or medical problems. In these cases, intervention is clearly indicated, yet there is little information about how best to treat such individuals. The field has been slow to develop criteria for abnormal grief reactions, and lack of such criteria has impeded development and testing of treatments. With the aid of a new instrument, the Inventory of Complicated Grief (ICG), we can now reliably identify a syndrome currently designated "traumatic grief." Found in 20% of bereaved persons, traumatic grief is associated with significant long-term morbidity. Symptoms of traumatic grief are distinct from symptoms of depression, and do not respond to standard treatments for depression. Therefore, we undertook development of a targeted Traumatic Grief Treatment (TGT). Pilot data in 10 patients show a robust treatment effect, much larger than that achieved by published reports of grief counseling. We now propose a randomized controlled trial to test the efficacy of TGT. Our primary aim is to compare effects of traumatic grief treatment (TGT) to a control, interpersonal psychotherapy (IPT) on measures of traumatic grief, depression, anxiety, functional impairment, self esteem and social support. We plan to conduct assessments of all randomized subjects at 16 weeks and 40 weeks. We will conduct exploratory analyses and instrument development to test and refine hypotheses related to putative mechanisms of action of TGT. We hypothesize that TGT will result in significantly greater improvement in traumatic grief than IPT, and that these differences will be sustained at 6-month follow-up. Almost a decade of work on the description and treatment of bereavement-related distress has prepared our research group for the treatment trial we now propose. We have come to understand who among those with bereavement-related symptomatology is at greatest risk for psychiatric and physical morbidity (i.e., those with traumatic grief) and we have developed what appears to be an effective intervention for this treatment-resistant population. The time is propitious for a controlled study of the efficacy of Traumatic Grief Treatment.

描述（根据申请人的摘要改编）：此申请请求 为5年研究的“创伤性悲伤”的治疗方法进行了资金。超过16 在美国，每年有百万人失控。实质性 少数派，悲伤是长期的，令人衰弱的，精神科或 医疗问题。在这些情况下，清楚地表明了干预措施 是关于如何最好地对待此类人的信息。该领域有 制定异常悲伤反应的标准很慢，缺乏这种标准 标准阻碍了治疗的发展和测试。借助 新乐器，复杂的悲伤（ICG）清单，我们现在可以可靠地可靠 确定当前指定为“创伤性悲伤”的综合症。在20％ 丧亲的人，创伤性悲伤与长期的重要长期有关 发病率。创伤性悲伤的症状与 抑郁症，不要对抑郁症的标准治疗做出反应。 因此，我们进行了针对性的创伤治疗的发展 （TGT）。 10名患者的试验数据显示出强大的治疗效果，大得多 比发表的悲伤咨询报告所实现的。我们现在建议 随机对照试验测试TGT的功效。我们的主要目的是 比较创伤性悲伤治疗（TGT）与对照，人际关系的影响 心理治疗（IPT）关于创伤性悲伤，抑郁，焦虑的度量 功能障碍，自尊和社会支持。我们计划进行 在16周零40周时对所有随机受试者的评估。我们将 进行探索性分析和仪器开发以测试和完善 假设与假定的TGT作用机理有关。我们假设这一点 TGT将导致创伤性悲伤的改善要比 IPT，这些差异将在6个月的随访中进行。几乎 在与丧亲有关的描述和处理方面的十年工作 困扰已经为我们的研究小组做好了治疗试验的准备 提出。我们已经了解与丧亲有关的人中的谁 症状学是精神病和身体发病率的最大风险 （即那些有创伤性悲伤的人），我们已经开发了似乎是一个 有效干预这种耐药人群。时间是 有利于对创伤治疗功效的对照研究。