LOW COST, HIGH QUALITY PREPOLARIZED MRI HEAD SCANNER

低成本、高质量预极化 MRI 头部扫描仪

• 批准号: 6173719
• 负责人: ALBERT MACOVSKI
• 金额: $ 15.32万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-05-01 至 2002-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6173719
• 关键词: bioimaging /biomedical imaging; biomedical equipment development; clinical biomedical equipment; head /neck neoplasm; magnetic resonance imaging; neoplasm /cancer diagnosis

DESCRIPTION (Adapted from Applicant's Abstract): The applicants proposed to build an ultra-low-cost and high-quality prototype Prepolarized MRI scanner for diagnosing head tumors. The overall goal of this research is to develop a new and innovative imaging modality that shows great potential for cancer screening, diagnosis and image-guided treatment. The specific aims are to design and build both a homogeneous, low-field electromagnet and a lowfrequency receiver system optimized for head imaging. The final aim is to integrate these subsystems with our working Prepolarized MRI system and to obtain an image of a normal volunteers head. This research is intended to demonstrate that Prepolarized MRI system contrast and SNR are equivalent to a conventional 0.5 T MRI system; and that this high-quality Prepolarized MRI system will cost less than $50,000 in capital costs. The successful development and integration of this innovative technology will require the application of several principles of engineering and science. For example, a homogeneous electromagnet design method draws from both electromagnetics and linear programming. A low-noise receiver subsystem design designed by the applicants relies on the principles of optimal RF receiver electronics. Pulse sequence design relies on the principles of MRI physics.

描述（改编自申请人的摘要）：申请人提出 构建超低成本和高质量的预极化 MRI 原型 用于诊断头部肿瘤的扫描仪。本研究的总体目标 是开发一种新的和创新的成像方式，显示出伟大的 癌症筛查、诊断和图像引导治疗的潜力。 具体目标是设计和建造一个均匀的低场 电磁体和针对头部优化的低频接收器系统 成像。最终目标是将这些子系统与我们的工作集成 预极化 MRI 系统并获取正常志愿者的图像 头。本研究旨在证明预极化 MRI 系统对比度和信噪比相当于传统的 0.5 T MRI 系统;这种高质量的预极化 MRI 系统的成本 资本成本低于 50,000 美元。的成功开发和 这项创新技术的整合需要应用 工程和科学的几个原理。例如，一个 均匀电磁体设计方法借鉴了电磁学 和线性规划。一种低噪声接收子系统设计 申请人依赖于最佳射频接收器的原理 电子产品。脉冲序列设计依赖于 MRI 原理 物理。