BIOGENESIS OF RIBOSOMES & SPLICEOSOMES IN SACCHAROMYCES CEREVISIAE

核糖体的生物发生

• 批准号: 6295118
• 负责人: JOHN L. WOOLFORD
• 金额: $ 1.17万
• 依托单位: MELLON PITTS CORPORATION (MPC CORP)
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-09-30 至 1999-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6295118
• 关键词: biological products; biomedical resource; biotechnology; computers; genetics; plants

Spliceosomes and ribosomes are ribonucleoprotein particles required for the excision of introns from and translation of mRNA in eukaryotic cells. The laboratory has focused on the protein components of these particles. We have cloned and anticipate cloning more, for these proteins and generated mutations in them in order to learn about their role in assembly and function of spliceosomes.

剪接体和核糖体是核糖核蛋白颗粒 从内含子中切除内含子和mRNA的翻译所需 真核细胞。 实验室专注于蛋白质 这些颗粒的组成部分。 我们已经克隆并期待克隆 更多，对于这些蛋白质和其中产生的突变，以便 了解它们在剪接体的组装和功能中的作用。