CORE--STATISTICAL

核心--统计

• 批准号: 6112231
• 负责人: ELIZABETH A BATES
• 金额: --
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-05-01 至 1999-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6112231
• 关键词: biomedical facility; statistical service /center; statistics /biometry

The Statistics Core is responsible for the coordination of scientific activity among the various projects and cores, and for budgetary planning, data base management, and statistical services. In addition, will promote the development of new analytic procedures tailored to the special problems that danger of capitalizing on chance when many different measures are taken with relatively small populations. Our solutions to this problem include (a)constraints on the level of analysis to which a strong hypothesis applies, (b) methods for aggregating multiple variables into a single robust variable, (c) constraints on the order in which hypotheses are tested, and/or constraints on the way that individual variables are used within a single complex model, and (d) a clear and fruitful separation between hypothesis testing (confirmatory analysis) and hypothesis generation (exploratory analysis). We also outline plans for integrative analyses across the populations under study within the Multicenter, including the construction of models that can be used for systematic cross- population comparisons.

统计核心负责科学协调 各个项目和核心之间的活动以及预算规划， 数据库管理和统计服务。 此外，还将推动 针对特殊问题开发新的分析程序 当采取许多不同的措施时，利用机会的危险 是针对相对较少的人群进行的。 我们对这个问题的解决方案 包括 (a) 对分析水平的限制 假设适用，（b）将多个变量聚合成一个变量的方法 单个稳健变量，(c) 对假设顺序的约束 进行测试，和/或对各个变量的方式进行限制 在单个复杂模型中使用，以及 (d) 清晰且富有成效的分离 假设检验（验证性分析）和假设之间 生成（探索性分析）。 我们还概述了综合计划 对多中心内研究的人群进行分析， 包括构建可用于系统交叉的模型 人口比较。