The UK National Crystallography Service 2022-27

英国国家晶体学服务中心 2022-27

• 批准号: EP/W02098X/1
• 负责人: Simon Coles
• 金额: $ 511.05万
• 依托单位: University of Southampton
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2022
• 资助国家: 英国
• 起止时间: 2022 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=EP%2FW02098X%2F1
• 关键词: UK; National; Crystallography; Service; 2022

The NCS facility is amongst the most powerful and highest throughput in the world. Through this next phase it will take a significant step that will clearly make it the world-leading facility. This will be achieved by harnessing upgrades to the latest cutting-edge X-ray technologies, coupled with a range of advanced techniques that expand the scope of crystallography studies that are accessible. Core business will be the ability to handle and examine samples that a typical academic crystallography unit cannot. New provision of the advanced techniques will enable crystallisation and dynamic experiments under non-ambient conditions and will cement the NCS's globally leading position. Investment in expertise and training the next generation continues to be central to the NCS, which will provide a rapid, professional and expert service for chemical crystallography to chemistry and related areas.The Core service will provide either raw/derived data being provided for processing, or a full analysis service taking a study through to publication. The ability to handle the most demanding samples in the UoS laboratory is a key feature, providing an effective filter for a follow-on synchrotron service. The NCS has regular access to the world-leading I19 beamline at Diamond Light Source. Thus, when required, the most powerful facilities are readily available to all of UK Chemistry and related disciplines, enabling rapid progress and cutting-edge research. It will be possible to perform advanced crystallographic experiments for feasibility, pump-priming or collaborative projects e.g. variable temperature, variable pressure and controlled gas environment studies. Customers from SMEs, spin-outs and large industry alike will have access to the same advanced facilities via commercial access to the professional, timely and bespoke service. Both novice and expert users will have access to appropriate training, from work-shadowing, introductory practical work and rudimentary data analysis, through to advanced analysis and solving the most demanding structural problems. A novel PG student apprenticeship scheme will extend NCS expertise out into individual departments.The NCS is well established in the research community with a proven ability to deliver a high profile and high throughput service and leads in many aspects, both nationally and globally. The facility has an exceptional publication record and is amongst the world's most prolific contributors to the CSD. The Director has been involved with NCS operations for 30 years, with the co-director working within the field for >20 years and a highly experienced team this gives a combined NCS staff expertise well in excess of 90 years. Professionalism is a trademark of the NCS - it prides itself in exemplary and rigorous processes for sample handling and tracking, data management and publishing, a bespoke user interface and an ability to deliver to a demanding set of KPIs. The environment in which the NCS is housed is ideally suited to its function. Governance and strategic direction of the facility is performed by an independent panel with wide-ranging expertise which presides over access, ensuring that the highest profile and impact science is being supported in the best possible way.Key new features for the NCS in this next phase of operation include:Reaching out to new users and sectors, the new crystallisation service underpins industry, SMEs and spin-outs, while dynamic experiments extend capability for academia;Completing upgrades to the next generation instrumentation will catapult the capability and capacity of the NCS to a new level for a lab-based facility;Several technician and apprentice schemes will train the next generation.

NCS 设施是世界上最强大、吞吐量最高的设施之一。通过下一阶段，它将迈出重要一步，显然将使其成为世界领先的设施。这将通过利用最新尖端 X 射线技术的升级，再加上一系列扩大晶体学研究范围的先进技术来实现。核心业务将是处理和检查典型学术晶体学单位无法处理和检查的样品的能力。新提供的先进技术将使结晶和动态实验能够在非环境条件下进行，并将巩固 NCS 的全球领先地位。对下一代专业知识和培训的投资仍然是 NCS 的核心，NCS 将为化学晶体学、化学及相关领域提供快速、专业和专家的服务。核心服务将提供用于处理的原始/衍生数据，或从研究到发表的完整分析服务。能够在 UoS 实验室处理最苛刻的样品是一项关键功能，为后续同步加速器服务提供有效的过滤器。 NCS 可以定期访问钻石光源的世界领先的 I19 光束线。因此，在需要时，英国所有化学和相关学科都可以随时使用最强大的设施，从而实现快速进展和前沿研究。可以进行先进的晶体学实验以实现可行性、泵启动或合作项目，例如可变温度、可变压力和受控气体环境研究。来自中小企业、衍生企业和大型行业的客户将可以通过专业、及时和定制服务的商业访问来使用相同的先进设施。新手和专家用户都将获得适当的培训，从工作观摩、介绍性实际工作和基本数据分析，到高级分析和解决最苛刻的结构问题。一项新颖的 PG 学生学徒计划将把 NCS 的专业知识扩展到各个部门。NCS 在研究界享有盛誉，拥有提供高知名度和高通量服务的能力，并在国内和全球许多方面处于领先地位。该机构拥有卓越的出版记录，是世界上 CSD 最多产的贡献者之一。总监参与 NCS 运营 30 年，联合总监在该领域工作超过 20 年，团队经验丰富，NCS 员工的综合专业知识已超过 90 年。专业精神是 NCS 的标志 - 它以样本处理和跟踪、数据管理和发布、定制用户界面以及交付一组严格的 KPI 的能力为荣，堪称典范且严格。 NCS 所在的环境非常适合其功能。该设施的治理和战略方向由具有广泛专业知识的独立小组执行，负责主持访问，确保以最佳方式支持最高知名度和影响力的科学。NCS 下一阶段的主要新功能运营包括：接触新用户和行业，新的结晶服务支撑工业、中小企业和衍生企业，而动态实验则扩展学术界的能力；完成下一代仪器的升级将提升能力将基于实验室的设施的 NCS 和能力提升到一个新的水平；一些技术人员和学徒计划将培训下一代。