Cardiovasomobility Research Training Program

心血管运动研究培训计划

基本信息

批准号：
10439465
负责人：
Mark A Supiano
金额：
$ 24.27万
依托单位：
UNIVERSITY OF UTAH
依托单位国家：
美国
项目类别：
财政年份：
2018
资助国家：
美国
起止时间：
2018-07-01 至 2024-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10439465
关键词：
Research Training Training Programs

项目摘要

Project Summary/Abstract This is a new T32 application to establish an innovative, interdisciplinary training program aimed at integrating mobility and cardiovascular health research at the University of Utah. Mobility and cardiovascular health are inextricably linked and hence the Cardiovasomobility Research Training Program (CRTP) will provide research training at the interface of these two important determinants of health and add to our understanding of their interactions. CRTP will be a comprehensive, interdisciplinary, bench-to-bedside training program building upon existing strengths at the University of Utah in the fields of physical function and cardiovascular medicine. The 28 participating faculty mentors selected for this training program are accomplished investigators with established research funding and mentoring experience. Faculty hail from the Departments of Internal Medicine, Radiology, Nutrition and Integrative Physiology, Physical Therapy, Mechanical and Bio-Engineering, and the Molecular Medicine Program; and represent many disciplines including exercise physiology, geriatric medicine, cardiology, molecular biology, metabolism, imaging, and physical therapy. Thus, the CRTP will span the translational spectrum of cardiovascular health and mobility research that will provide a unique opportunity for the program’s trainees to both parse out and integrate these important determinants of health. The CRTP has four Specific Aims: 1) To provide administrative structure and oversight for research training in cardiovasomobility; 2) To provide trainee-specific career development that includes comprehensive training and mentorship in the integration of mobility and cardiovascular health research; 3) To evaluate programmatic outcomes; and 4) To recruit and support a diverse group of trainees with respect to gender and racial composition. The program requests support for 2 Pre-Doctoral and 3 Post-Doctoral (MD or PhD) trainee positions. Pre-Doctoral trainees will be recruited from the graduate programs in Nutrition and Integrative Physiology, Rehabilitation Science, MD/PhD, and Bioscience PhD Programs. MD Post-Doctoral trainees will be drawn largely from the clinical fellowship programs and PhD Post-Doctoral trainees will be recruited from individuals applying to join the research programs of participating faculty mentors. The training program will be led by two very experienced investigators – an exercise physiologist and a geriatrician – to ensure comprehensive and appropriate support of the program’s physician and non-physician trainees. They will be supported by an outstanding group of committed and experienced colleagues who will serve as the program’s Executive Committee. An External Advisory Committee will be formed to provide additional programmatic review. The University of Utah is poised to respond to the need to train the next generation of research investigators in the integration of mobility and cardiovascular health by offering this comprehensive, interdisciplinary CRTP.

项目概要/摘要这是一个新的 T32 应用程序，旨在建立创新的跨学科培训计划，旨在整合犹他大学的流动性和心血管健康研究是流动性和心血管健康。密不可分，因此心血管活动研究培训计划 (CRTP) 将提供研究在这两个重要的健康决定因素的界面上进行培训，并增加我们对它们的理解 CRTP 将是一个全面的、跨学科的、从实验室到临床的培训计划。犹他大学在身体机能和心血管医学领域的现有优势。参加本次培训计划的 28 名参与教师导师都是具有丰富经验的研究人员已建立的研究经费和指导经验的教师来自内部部门。医学、放射学、营养与综合生理学、物理治疗、机械与生物工程、和分子医学项目；并代表许多学科，包括运动生理学、老年医学因此，CRTP 将涵盖医学、心脏病学、分子生物学、新陈代谢、成像和物理治疗。心血管健康和流动性研究的转化范围将提供独特的机会让该计划的学员解析并整合这些重要的健康决定因素。 CRTP 有四个具体目标： 1) 为以下领域的研究培训提供行政结构和监督： 2) 提供针对学员的职业发展，包括综合培训以及对流动性和心血管健康研究整合的指导；3) 评估计划性结果；4) 招募和支持不同性别和种族的学员群体该项目需要支持 2 名博士前和 3 名博士后（医学博士或博士）实习生。博士前实习生将从营养和综合研究生项目中招募。生理学、康复科学、医学博士/博士和生物科学博士后培训生将。主要来自临床研究金计划，博士后培训生将从个人参加参与教师导师的研究计划。由两名经验丰富的研究人员（一名运动生理学家和一名老年病学家）领导，以确保他们将为该计划的医师和非医师实习生提供全面和适当的支持。得到了一群杰出的忠诚且经验丰富的同事的支持，他们将作为该计划的将成立一个外部咨询委员会来提供额外的计划。犹他大学准备满足培训下一代研究的需求。研究人员通过提供这种全面的、跨学科的 CRTP。

项目成果

期刊论文数量（50）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

The muscle reflex and chemoreflex interaction: ventilatory implications for the exercising human.

肌肉反射和化学反射相互作用：对锻炼者的通气影响。

DOI：
发表时间：
2020-10-01
期刊：
影响因子：
0
作者：
Wan, Hsuan;Weavil, Joshua C;Thurston, Taylor S;Georgescu, Vincent P;Bledsoe, Amber D;Jessop, Jacob E;Buys, Michael J;Richardson, Russell S;Amann, Markus
通讯作者：
Amann, Markus

Ascorbate attenuates cycling exercise-induced neuromuscular fatigue but fails to improve exertional dyspnea and exercise tolerance in COPD.

抗坏血酸可以减轻骑车运动引起的神经肌肉疲劳，但不能改善慢性阻塞性肺病患者的劳力性呼吸困难和运动耐量。

DOI：
发表时间：
2021-01-01
期刊：
影响因子：
0
作者：
Hureau, Thomas J;Weavil, Joshua C;Sidhu, Simranjit K;Thurston, Taylor S;Reese, Van R;Zhao, Jia;Nelson, Ashley D;Birgenheier, Nathaniel M;Richardson, Russell S;Amann, Markus
通讯作者：
Amann, Markus

On the implication of dietary nitrate supplementation for the hemodynamic and fatigue response to cycling exercise.

膳食硝酸盐补充剂对自行车运动的血流动力学和疲劳反应的影响。

DOI：
发表时间：
2021-12-01
期刊：
影响因子：
0
作者：
Thurston, Taylor S;Weavil, Joshua C;Hureau, Thomas J;Gifford, Jayson R;Georgescu, Vincent P;Wan, Hsuan;La Salle, D Taylor;Richardson, Russell S;Amann, Markus
通讯作者：
Amann, Markus

Impact of aging on the work of breathing during exercise in healthy men.

衰老对健康男性运动时呼吸功的影响。

DOI：
发表时间：
2022-03-01
期刊：
影响因子：
0
作者：
Weavil, Joshua C;Thurston, Taylor S;Hureau, Thomas J;Gifford, Jayson R;Aminizadeh, Soheil;Wan, Hsuan;Jenkinson, Robert H;Amann, Markus
通讯作者：
Amann, Markus

Critical considerations of the contribution of the corticomotoneuronal pathway to central fatigue.

皮质运动神经元通路对中枢疲劳的贡献的关键考虑。