Summer Medical student Aging and Alzheimer disease Research Training (SMAART) program

暑期医学生衰老和阿尔茨海默病研究培训 (SMAART) 计划

• 批准号: 10411754
• 负责人: Joshua Grill
• 金额: $ 6.64万
• 依托单位: UNIVERSITY OF CALIFORNIA-IRVINE
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-06-01 至 2027-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10411754
• 关键词: Aging; Alzheimer' s Disease; Alzheimer' s disease related dementia; Basic Science; Biological Markers; Biometry; Caring; Clinical Sciences; Competence; Educational Curriculum; Epidemiology; Ethics; Fostering; Generations; Genetic; Journals; Knowledge; Leadership; Liquid substance; Medical Students; Mentors; Molecular and Cellular Biology; Neuropsychology; Neurosciences; Patients; Physicians; Public Health; Publishing; Research; Research Activity; Research Design; Research Methodology; Research Personnel; Research Training; Scientist; Students; Training; Training Programs; Translational Research; career; career development; clinical care; experience; flexibility; hands on research; innovation; medical schools; multidisciplinary; neuroimaging; programs; skills; translational physician

Summary/Abstract: Alzheimer's disease and related dementias (ADRD) is a public health crisis compounded by the insufficient number of skilled clinicians and investigators with high quality training and expertise to provide care and conduct translational research. It is vital to foster a new generation of physician researchers that possess a diverse array of knowledge and skills, including understanding basic (genetics, molecular and cellular biology, neuroscience), patient level (clinical care, neuropsychology, fluid biomarkers, neuroimaging, epidemiology), and cross cutting (biostatistics, ethics) research design and methods. Thus our proposed SMAART T35 program will grow the pipeline of medical students with research experiences inspiring new physician scientists to focus their careers in the ADRD space. The low availability of skilled ADRD translational physician scientists represents a threat to the national ADRD research agenda. Therefore, in this T35 application we propose to engage MD students in hands on research, mentoring, publishing, career development and leadership. Through our leadership expertise in multidisciplinary translational ADRD research we aim to enhance the diversity and availability of physician scientists through these three specific aims: 1) Champion mentored career development by providing an integrated program that consists of outstanding leadership and oversight at all levels. 2) Create a flexible and innovative curriculum that emphasizes both core and advanced competencies in clinical, translational, and basic science 3) Maximizing access to Summer Mentoring and Research Training (SMAART) Program. Through formal check ins and ADRD themed journal clubs, trainees will receive guidance and support from the Program directors. The program will longitudinally track students through the four years of medical school encouraging continued engagement in research activities.

摘要/摘要： 阿尔茨海默氏病和相关痴呆症（ADRD）是一场公共卫生危机，但由于缺乏足够的治疗措施而加剧了这一危机。 大量受过高质量培训和专业知识的熟练临床医生和研究人员，以提供护理和 进行转化研究。培养具有一定专业知识的新一代医师研究人员至关重要 各种知识和技能，包括了解基础知识（遗传学、分子和细胞生物学、 神经科学）、患者层面（临床护理、神经心理学、液体生物标志物、神经影像学、流行病学）、 和跨领域（生物统计学、伦理学）研究设计和方法。因此我们提出的 SMART T35 该计划将扩大医学生的输送渠道，并通过研究经验激励新的医师科学家 将他们的职业生涯集中在 ADRD 领域。缺乏熟练的 ADRD 转化医师科学家 对国家 ADRD 研究议程构成威胁。因此，在此 T35 应用中，我们建议 让医学博士学生参与研究、指导、出版、职业发展和领导力。 通过我们在多学科转化 ADRD 研究方面的领导专业知识，我们的目标是增强 通过以下三个具体目标实现医师科学家的多样性和可用性：1）冠军指导 通过提供由杰出领导和监督组成的综合计划来实现职业发展 在各个层面。 2）创建灵活创新的课程，强调核心和高级 临床、转化和基础科学方面的能力 3) 最大限度地获得暑期指导和 研究培训 (SMAART) 计划。通过正式签到和 ADRD 主题期刊俱乐部，学员 将得到项目主管的指导和支持。该计划将纵向跟踪学生 在医学院的四年里，鼓励继续参与研究活动。