Chemical Exposure Facility Core

化学暴露设施核心

• 批准号: 10383764
• 负责人: Kim A. Anderson
• 金额: $ 18万
• 依托单位: OREGON STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-07-01 至 2025-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10383764
• 关键词: Analytical Chemistry; Aromatic Polycyclic Hydrocarbons; Assessment tool; Biological; Chemical Exposure; Chemicals; Collaborations; Communities; Community Health; Complement; Consultations; Core Facility; Custom; Data; Devices; Diagnosis; Disease; Endocrine Disruptors; Environment; Environmental Epidemiology; Environmental Exposure; Environmental Health; Evaluation; Exposure to; Flame Retardants; Foundations; Frequencies; Gravitation; Health; Health Personnel; Health Sciences; Human; Human Biology; Industrialization; Infrastructure; Intervention; Investments; Learning; Link; Manufacturer Name; Measures; Metals; Methodology; Methods; Mission; Modeling; Monitor; Organic Chemicals; Pacific Northwest; Participant; Pathway interactions; Persons; Pesticides; Pharmacologic Substance; Polychlorinated Biphenyls; Population; Protocols documentation; Public Health; Research; Research Personnel; Resources; Sampling; Scientist; Services; Silicones; Techniques; Technology; Toxic Environmental Substances; Toxicology; adverse outcome; analytical method; community engagement; community organizations; consumer product; cost; data visualization; disadvantaged population; disorder prevention; epidemiology study; experience; faculty community; health science research; improved; innovation; member; novel; phthalates; prospective; volatile organic compound

PROJECT SUMMARY - Chemical Exposure Facility Core (CXC) The Chemical Exposure Facility Core (CXC), directed by Kim Anderson, supply passive sampling devices (PSDs) and analytical services to advance environmental health science. Members of the EHS CC will apply PSDs and our analytical methods to provide decision support for stakeholders such as community organizations, manufacturers, regulators, legislators, NGOs, health care providers, and pharmaceutical firms. Accurately assessing the breadth of a person's exposures to environmental toxicants is central to the challenge of studying environmental health effects. The CXC offers directly analytical methods for over 1,500 organic chemicals and facilitates additional chemical analyses through our additional campus resources. The lack of low cost, easy-to-use personal sampling technology hinders epidemiological studies, especially in disadvantaged populations. Over the last several years with OSU and EHS Core Center investments have built personal sampling wristband technology with unique analytical methods. We made these investments, specifically because Public Health faculty and Community partners were enthusiastic about its broad potential to fill a key gap in Public Health. Our passive wristband sampler was developed to provide a relevant, quantifiable assessment of chemical bioavailable exposure. The passive sampling platform including wristbands will form the foundation for providing new and critical resources for Center researchers to measure organic chemicals that are a crucial component of the chemical exposures. Over 1,500 volatile and semi-volatile organic chemicals can be quantified. Through our core, in partnership with the Integrated Health Sciences Facility Core and Community Engagement Cores, we enhance and stimulate many partnerships and collaborative efforts using the analytical methods and passives sampling/wristband platform as the gravitational force that bring researchers, public health experts, community organizations and citizens together. Passive samplers naturally stimulate collaborative research relationships and interdisciplinary teams. The Core will provide center investigator and study participants and their communities, novel and appropriate data visualization of our wristband data. The CXC will extract and analyze chemical mixtures, thereby enabling EHS CC members to measure concentrations of environmental toxicants.

项目摘要 - 化学暴露设施核心 (CXC) Kim Anderson 领导的化学暴露设施核心 (CXC) 提供被动采样设备 （PSD）和分析服务，以推进环境健康科学。 EHS CC 成员将提出申请 PSD 和我们的分析方法为社区等利益相关者提供决策支持 组织、制造商、监管机构、立法者、非政府组织、医疗保健提供者和制药公司。 准确评估一个人接触环境有毒物质的程度是这一挑战的核心 研究环境健康影响。 CXC 为 1,500 多种有机化合物提供直接分析方法 化学品并通过我们额外的校园资源促进额外的化学分析。缺乏 低成本、易于使用的个人采样技术阻碍了流行病学研究，特别是在 弱势群体。在过去的几年里，OSU 和 EHS 核心中心的投资已经建立 个人采样腕带技术具有独特的分析方法。我们进行了这些投资， 特别是因为公共卫生教师和社区合作伙伴对其广泛的潜力充满热情 填补公共卫生领域的一个关键空白。我们开发的无源腕带采样器旨在提供相关的、 化学生物利用度暴露的量化评估。被动采样平台包括 腕带将为中心研究人员提供新的关键资源进行测量奠定基础 有机化学品是化学品暴露的重要组成部分。超过 1,500 种挥发性和半挥发性物质 有机化学品可以量化。通过我们的核心，与综合健康科学合作 设施核心和社区参与核心，我们加强和促进许多伙伴关系和 使用分析方法和无源采样/腕带平台作为协作努力 吸引研究人员、公共卫生专家、社区组织和公民的引力 一起。被动采样器自然会激发协作研究关系和跨学科团队。 核心将为中心研究者和研究参与者及其社区提供新颖且适当的信息 我们的腕带数据的数据可视化。 CXC 将提取和分析化学混合物，从而使 EHS CC 成员测量环境毒物的浓度。