FUNCTIONAL IMAGING OF STRIATE CORTEX

纹状皮层的功能成像

• 批准号: 2160557
• 负责人: GARY G BLASDEL
• 金额: $ 25.91万
• 依托单位: HARVARD MEDICAL SCHOOL
• 依托单位国家: 美国
• 财政年份: 1988
• 资助国家: 美国
• 起止时间: 1988-08-01 至 1997-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2160557
• 关键词: Macaca; brain imaging /visualization /scanning; brain mapping; cerebral dominance; dyes; electrophysiology; light microscopy; microelectrodes; neural information processing; visual cortex

Results using an optical approach to study patterns of cortical organization suggest that response properties in addition to ocular dominance and orientation may be organized laterally (tangentially). Funds are requested in the present proposal to continue this analysis, using optical imaging to find functional organizations that are then explore in greater detail with microelectrodes. In one group of experiments, cortical magnification will be determined optically along different axes so that anisotropies related to ocular dominance and orientation can be determined. In light of the recent convergence of findings from different labs obtained with somewhat different techniques, funds are also requested to compare results obtained from the same cortical regions before and after the application of voltage sensitive dye. These experiments are designed to increase our understanding of visual information processing and associated structure-function relationships in the upper layers of monkey striate cortex.

使用光学方法研究皮质模式的结果 组织表明，除了眼睛之外，反应特性 主导和方向可以横向（切向）组织。 本提案要求提供资金以继续进行这项分析， 使用光学成像来寻找功能组织，然后 使用微电极进行更详细的探索。 在一组中 实验中，皮质放大率将通过光学方式确定 不同的轴，以便与眼部优势相关的各向异性和 可以确定方向。 鉴于最近的融合 不同实验室通过不同技术获得的结果， 还要求提供资金来比较从同一项目中获得的结果 应用电压敏感之前和之后的皮质区域 染料。 这些实验旨在加深我们对 视觉信息处理和相关的结构功能 猴子纹状皮层上层的关系。