FUNCTIONAL IMAGING OF STRIATE CORTEX

纹状皮层的功能成像

• 批准号: 2160557
• 负责人: GARY G BLASDEL
• 金额: $ 25.91万
• 依托单位: HARVARD MEDICAL SCHOOL
• 依托单位国家: 美国
• 财政年份: 1988
• 资助国家: 美国
• 起止时间: 1988-08-01 至 1997-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2160557
• 关键词: Macaca; brain imaging /visualization /scanning; brain mapping; cerebral dominance; dyes; electrophysiology; light microscopy; microelectrodes; neural information processing; visual cortex; Macaca; brain imaging /visualization /scanning; brain mapping; cerebral dominance; dyes; electrophysiology; light microscopy; microelectrodes; neural information processing; visual cortex

Results using an optical approach to study patterns of cortical organization suggest that response properties in addition to ocular dominance and orientation may be organized laterally (tangentially). Funds are requested in the present proposal to continue this analysis, using optical imaging to find functional organizations that are then explore in greater detail with microelectrodes. In one group of experiments, cortical magnification will be determined optically along different axes so that anisotropies related to ocular dominance and orientation can be determined. In light of the recent convergence of findings from different labs obtained with somewhat different techniques, funds are also requested to compare results obtained from the same cortical regions before and after the application of voltage sensitive dye. These experiments are designed to increase our understanding of visual information processing and associated structure-function relationships in the upper layers of monkey striate cortex.

使用光学方法研究皮质模式的结果 组织建议除眼睛以外的响应特性 优势和方向可以横向组织（切向）。 本提案中要求资金继续进行此分析， 使用光学成像来查找当时的功能组织 用微电极更详细地探索。 一组 实验，皮层放大倍数将沿着光学确定 不同的轴以使各向异性与眼部优势和 可以确定方向。 鉴于最近的融合 从不同实验室获得的发现，以某种不同的技术获得 还要求资金比较从相同的结果获得的结果 施用电压敏感之前和之后的皮质区域 染料。 这些实验旨在增加我们对 视觉信息处理和相关的结构功能 猴子横纹皮层上层的关系。