Indiana University Kidney Training Program (IU-KTP)

印第安纳大学肾脏训练计划 (IU-KTP)

• 批准号: 10203951
• 负责人: Sharon M Moe
• 金额: $ 28.66万
• 依托单位: INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-07-01 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10203951
• 关键词: Indiana; Kidney; Training Programs; Universities

DESCRIPTION: The goal of the Indiana University School of Medicine’s Kidney Research Program for Research Training in Translational Kidney Research is to provide a highly integrative, multi-disciplinary experience that increases the probability that trainees will maintain an interest in basic and clinical kidney research. The IU-KTP is well poised to train the next generation of scientists to lead the charge in halting the increase in kidney disease and reduce health care costs by personalizing the approach to diagnosis and treatment. Importantly, our program will afford Trainees the opportunity to study both Adult and Pediatric Kidney Diseases with collaboration along the T1-T4 translational research spectrum in order to bring new therapies and innovations to the field of Nephrology. This new program capitalizes on IUSM’s strength in this critical area of medical research and is directly supported by 30 faculty mentors from 8 different departments with collectively over $30 million in direct annual extramural funding. These national and international leaders have outstanding track records in cutting edge, mechanistic research and in the training of PhD and MD post- doctoral fellows. The research training opportunities are broadly categorized across three programmatic themes that highlight the collaborative research in kidney disease at IU: The pathogenesis of kidney disease (AKI, diabetes, kidney stones, childhood urologic disorders), precision medicine of diagnostics and therapeutics, and complications of CKD (CKD-mineral bone disorder, immobility, and drug dispensation). These programmatic themes capitalize on our Adult and Pediatric Divisions of Nephrology that allow trainees access to innovative technologies and methodologies, augmented by Institutional Resources. The IU-KTP program will build upon 1) The successful and innovative NIH funded research in our Adult and Pediatric Nephrology programs, 2) Our state of the art kidney imaging techniques centered with the NIDDK funded George O’Brien Center; 3) The robust precision ‘omics’ infrastructure at Indiana University and in the Divisions, 4) Our translational approaches fueled by our impressive clinical research infrastructure in Nephrology and our nationally renowned CTSI and 5) The collaborative spirit of IU SOM campus investigators. Importantly, the outstanding scientific training environment supporting IU-KTP Trainees will be further augmented by a comprehensive, integrative, and formal career development program with the long-term goal of these individuals becoming the next generation of Kidney Researchers, Leaders and Mentors.

描述：印第安纳大学医学院肾脏研究计划的目标 转化肾脏研究的研究培训旨在提供高度综合、多学科的培训 增加学员对基础和临床肾脏保持兴趣的可能性的经验 IU-KTP 已准备好培训下一代科学家，以带头制止这种现象。 通过个性化诊断和治疗方法，减少肾脏疾病的增加并降低医疗费用 重要的是，我们的计划将为学员提供学习成人和儿童的机会。 肾脏病领域与 T1-T4 转化研究领域开展合作，以带来新的成果 这项新计划充分利用了 IUSM 在这方面的优势。 医学研究的关键领域，并由来自 8 个不同部门的 30 名教师导师直接支持 这些国家和国际领导人每年总共获得超过 3000 万美元的直接外部资金。 在尖端机械研究以及博士和医学博士后培训方面拥有出色的记录 研究培训机会大致分为三个项目。 强调印第安纳大学肾脏疾病合作研究的主题：肾脏疾病的发病机制 （AKI、糖尿病、肾结石、儿童泌尿系统疾病）、诊断和精准医疗 CKD 的治疗和并发症（CKD-矿物质性骨病、不动和药物分配）。 这些计划主题利用了我们的成人和儿科肾病科，使学员能够 获得创新技术和方法，并得到 IU-KTP 的增强。 该计划将建立在 1) NIH 资助的成人和儿科研究的成功和创新基础上 肾脏病学项目，2) 我们以 NIDDK 资助的最先进的肾脏成像技术为中心 乔治·奥布莱恩中心；3) 印第安纳大学及其各部门强大的精密“组学”基础设施， 4) 我们的转化方法由我们令人印象深刻的肾脏病学临床研究基础设施和我们的 全国知名的 CTSI 和 5) IU SOM 校园研究人员的协作精神。 支持 IU-KTP 学员的卓越科学培训环境将通过 全面、综合、正式的职业发展计划，并具有这些目标的长期目标 成为下一代肾脏研究人员、领导者和导师的个人。