Indiana Clinical and Translational Sciences Institute

印第安纳临床与转化科学研究所

• 批准号: 10153909
• 负责人: Sharon M Moe
• 金额: $ 559.79万
• 依托单位: INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-05-18 至 2023-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10153909
• 关键词: Abbreviations; Address; Automobile Driving; Chronic Disease; Clinical; Clinical Research; Clinical Sciences; Clinical and Translational Science Awards; Collaborations; Communities; Community Health; Contracts; County; Development; Discipline; Disease; Disease Management; Electronic Health Record; Enrollment; Environment; Face; Fostering; Foundations; Funding Opportunities; Goals; Government; Health; Health system; Healthcare; Healthcare Systems; Hospitals; Human; Indiana; Infant Mortality; Informatics; Infrastructure; Institutes; Institutional Review Boards; Intervention; Journals; Knowledge; Laboratories; Longevity; Methodology; Methods; Midwestern United States; Mission; Obesity; Opiate Addiction; Patients; Peer Review; Phase; Population; Positioning Attribute; Process; Publications; Research; Research Personnel; Research Training; Resources; Schools; Science; Secure; Services; System; Textiles; Therapeutic; Training; Training Programs; Training and Education; Translational Research; United States National Institutes of Health; Universities; Vision; Work; arm; career development; catalyst; community engagement; community partnership; data dissemination; data warehouse; design; health disparity; improved; innovation; medical schools; meetings; member; mortality disparity; novel strategies; patient engagement; population health; precision medicine; programs; public-private partnership; tool; volunteer

Contact PD/PI: Shekhar, Anantha INDIANA CLINICAL AND TRANSLATIONAL SCIENCES INSTITUTE: OVERALL SUMMARY/ABSTRACT The Indiana Clinical and Translational Sciences Institute (Indiana CTSI) was created in 2008 as a statewide laboratory to accelerate clinical and translational research by the three research universities, Indiana, Purdue and Notre Dame, with partner health care systems, local foundations and corporate partners. The mission of the Indiana CTSI is to serve as the statewide catalyst for translational research and improve human health across Indiana, the nation and beyond. The Indiana CTSI fosters a collaborative research environment, provides resources and services to conduct the highest-quality clinical and translational research, offers education and training programs to build a robust translational workforce, engages our community as a partner at all levels, and functions as an exemplary member of the national CTSA network. The principle of continuous innovation cycle of “4Ds”: Design, Demonstrate, Duplicate, and Disseminate guides the Indiana CTSI. The CTSI plans to accomplish its mission through five Specific Aims: Aim I. Expand education and training to build a broader array of translational workforce through its Career development, Education and Research Training (CERT) and related suite of programs. Aim II. Build on the robust Indiana translational research environment of collaboration and engagement with its outstanding Community Health Partnership (CHeP) program and its public-private partnerships throughout the state and beyond. Aim III. Further, strengthen the CTSI’s integrated approach to support translational research across all phases and many scientific disciplines through its Project Development Teams (PDTs), and include a wide variety of populations across the lifespan. Aim IV. Promote scientific approaches to design and implement the best methods and processes that accelerate the transit of ideas and health interventions across the translational stages to reach patients faster. Aim V. Expand on the exceptional capabilities of the Indiana Translational Informatics Program (iTIP). During the next 5 years, the Indiana CTSI 3.0 will not only expand translational research across the state, but also address some of the major community health issues faced by Indiana and the nation. In this section, we first describe the transformative impact the Indiana CTSI has had on the local environment, and outline how it is poised to make greater impact locally and contribute to NCATS’s mission as an ideal Hub in the national CTSA network. Frequently used abbreviations: All IN – All Indiana Health & Research; CERT – Career development, Education and Research Training; CHeP – Community Health Partnerships; CTR – Clinical & Translational Research; EC – Executive Council; iTIP – Indiana Translational Informatics Program; IUB– Indiana University, Bloomington; IUPUI – Indiana University–Purdue University Indianapolis; IU Health – Indiana University Health hospitals; IUSM – Indiana University School of Medicine; ND – University of Notre Dame; PDT – Project development team; PEC – Patient Engagement Core; PU – Purdue University; RKS – Regulatory Knowledge and Support; SERVE – Subject Engagement and Research Volunteer Enrollment. Project Summary/Abstract Page 704 Contact PD/PI: Shekhar, Anantha

联系人 PD/PI：Shekhar、Anantha 印第安纳临床与转化科学研究所：总体 摘要/摘要 印第安纳临床与转化科学研究所 (Indiana CTSI) 成立于 2008 年，是一家联邦机构 实验室加速印第安纳州和普渡大学三所研究型大学的临床和转化研究 和圣母大学，以及合作伙伴医疗保健系统、当地基金会和企业合作伙伴的使命。 印第安纳州 CTSI 旨在成为转化研究和改善人类健康的田园催化剂 印第安纳州 CTSI 在印第安纳州、全国乃至其他地区营造了一个协作研究环境， 提供资源和服务来进行最高质量的临床和转化研究，提供 教育和培训计划旨在建立一支强大的转化劳动力队伍，让我们的社区成为合作伙伴 并作为国家 CTSA 网络的模范成员。 “4D”创新周期：设计、演示、复制和传播指导着印第安纳州 CTSI。 CTSI 计划通过五个具体目标来完成其使命： 目标 I. 扩大教育和培训以建立 通过职业发展、教育和研究培训培养更广泛的转化劳动力 (CERT) 和相关的计划套件基于强大的印第安纳州转化研究环境。 与其杰出的社区健康伙伴关系 (CHeP) 计划及其 目标 III 进一步加强 CTSI 的合作。 通过综合方法支持跨所有阶段和许多科学学科的转化研究 其项目开发团队 (PDT)，包括整个生命周期的各种人群。 推广科学方法来设计和实施最佳方法和流程，以加速 跨转化阶段的思想和健康干预措施的传递，以更快地到达患者手中。 下一步将扩展印第安纳翻译信息学计划 (iTIP) 的卓越能力。 5 年来，印第安纳州 CTSI 3.0 不仅将扩大全州的转化研究，还将解决 在本节中，我们首先描述印第安纳州和国家面临的一些主要社区健康问题。 印第安纳州 CTSI 对当地环境产生的变革性影响，并概述了它将如何做好准备 在当地产生更大的影响，并为 NCATS 作为国家 CTSA 网络中的理想中心的使命做出贡献。 常用缩写：All IN – 所有印第安纳州健康与研究中心 – 职业发展； 教育和研究培训；CHeP – 社区健康合作伙伴关系 – 临床与转化； 研究；EC – 执行理事会；iTIP – 印第安纳州转化信息学计划； 大学，布卢明顿；印第安纳大学印第安纳大学-普渡大学印第安纳波利斯分校； 大学健康医院；IUSM – 印第安纳大学医学院；ND – 圣母大学； PDT – 项目开发团队；PEC – 患者参与核心；PU – 普渡大学 监管知识和支持；服务——学科参与和研究志愿者招募。 项目摘要/摘要第 704 页 联系人 PD/PI：Shekhar、Anantha