PRIDE-Functional and Translational Genomics of Blood Disorders

PRIDE-血液疾病的功能和转化基因组学

• 批准号: 10557179
• 负责人: Betty Sue Pace
• 金额: $ 34.41万
• 依托单位: AUGUSTA UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-09-20 至 2024-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10557179
• 关键词: 3-Dimensional; Achievement; Address; African American; Applications Grants; Award; Behavioral Sciences; Biomedical Research; Black race; Collaborations; Committee Members; Data; Development; Disabled Persons; Educational Curriculum; Educational process of instructing; Ethnic Population; Extramural Activities; Faculty; Fostering; Funding; Funding Mechanisms; Goals; Grant; Grant Review; Health; Hematological Disease; Home; Individual; Inequity; Institution; Investigator-Initiated Research; Leadership; Mentors; Mentorship; Monitor; National Heart, Lung, and Blood Institute; Obesity; Pilot Projects; Principal Investigator; Private Sector; Process; Program Evaluation; Protein Analysis; Public Sector; Reporting; Research; Research Personnel; Research Project Grants; Research Training; Resources; Scientist; Signal Recognition Particle; Teacher Professional Development; Technical Expertise; Testing; Texas; Training; Training Programs; Training Support; Underrepresented Minority; United States; United States National Institutes of Health; Universities; Visit; Writing; career; cohort; design; empowerment; experience; faculty mentor; functional genomics; hands-on learning; health disparity; improved; innovation; matriculation; meetings; member; multidisciplinary; novel; peer; programs; racial population; skills; statistics; success; summer institute; translational genomics

Abstract The lack of diversity remains a significant challenge in biomedical and behavioral science research programs and faculty composition in US academic centers. The National Heart, Lung, and Blood Institute (NHLBI) funded the Summer Institute Program to Increase Diversity (SIPID) in 2006. Subsequently, the Program to Increase Diversity Among Individuals Engaged in Health-Related Research-Functional and Translational Genomics of Blood Disorders (PRIDE-FTG) was established at Augusta University. Through the PRIDE-FTG program, we provided mentored training for 76 underrepresented minority junior faculty investigators. Mentees learned hands-on bench research and grantsmanship skills during two consecutive Summer Institutes. Program evaluation supports the achievement of our primary goal of aiding mentees to submit an NIH or equivalent grant application within two years of program completion, demonstrated by a 41.7% NIH grant-funding rate as principal investigator. We propose to continue this mentored training with the next iteration of PRIDE-FTG, expanded to include several innovative components and collaboration with the Obesity Health Disparities- PRIDE program to pool federal resources. We will test the hypothesis that a mentored training program to build research and grant-writing skills will increase the ability of URM and disabled faculty, conducting blood disorders research to obtain extramural funding and transition to independent research careers. Four aims will be accomplished: AIM 1. Conduct Innovative Summer Institute 1 at Augusta University (Component 1). Mentees matriculating into the PRIDE-FTG program will participate in a multidisciplinary curriculum including hands-on-bench research training and grant-writing activities to develop funding strategies. AIM 2. Support Small Research Project Funding Initiative (Component 4). In collaboration with the PRIDE Steering Committee and NHLBI program staff, the PRIDE-FTG program will fund focused pilot projects to support competitive grant proposals addressing blood disorders research. AIM 3. Facilitate Mentoring and Networking Activities (Component 2). Mentorship Committees comprised of a mentee, a PRIDE research mentor and home institution mentor will be established. Peer-mentorship teams will launch within cohorts to promote research collaboration. The program will support a mid-year visit to the mentor’s institution and attendance at the consortium-wide PRIDE annual meeting. AIM 4: Conduct Innovative Summer Institute 2 (Component 3). Mentees will return to Augusta University to complete a one-on-one grant review to meet the primary goal of the PRIDE program to submit an NIH or equivalent grant application and participate in additional research experiences. The mentored training supported by the PRIDE-FTG program will influence the number of underrepresented and disabled scientists achieving successful biomedical research careers.

抽象的 在生物医学和行为科学研究计划中，缺乏多样性仍然是一个重大挑战 和美国学术中心的教师组成。国家心脏，肺和血液研究所（NHLBI）资助 夏季研究所计划在2006年增加多样性（SIPID）。随后，该计划增加 从事与健康有关的研究功能和转化基因组学的个人之间的多样性 血液疾病（Pride-FTG）在奥古斯塔大学建立。通过Pride-FTG计划，我们 为76名代表性不足的少数民族初级教师调查员提供了指导的培训。受训者学会了 连续两个夏季学院的实践替补席研究和授予技巧。程序 评估支持我们的主要目标，即协助修改提交NIH或同等学历 在完成计划完成的两年内授予申请，由41.7％的NIH赠款利率证明 首席研究员。我们建议通过下一个骄傲ftg的迭代来继续进行这种修改的培训， 扩展到包括几个创新组件以及与肥胖健康差异的合作 - 骄傲计划以汇集联邦资源。我们将检验以下假设，即一项指导的培训计划以建立 研究和授予写作技巧将提高URM和残疾教师的能力，进行血液 疾病的研究以获得壁外资金并过渡到独立的研究职业。四个目标将 要完成：目标1。在奥古斯塔大学（组成1）进行创新的夏季研究所1。 训练学训练计划的训练学计划将参加多学科课程 实践基础研究培训和授予写作活动，以制定资金策略。目标2。支持 小型研究项目资金计划（组件4）。与骄傲指导委员会合作 和NHLBI计划人员，Pride-FTG计划将资助专注的试点项目，以支持竞争性赠款 解决血液疾病研究的建议。目标3。促进指导和网络活动 （组件2）。指导委员会包括受训者，骄傲的研究导师和家庭 机构导师将建立。同行纪念团队将在队列中启动以促进研究 合作。该计划将支持对导师机构进行的访问，并参加 整个财团的骄傲年会。目标4：进行创新的夏季研究所2（组件3）。 受训者将返回奥古斯塔大学，完成一对一的赠款审查，以实现 提交NIH或同等赠款申请并参与其他研究的骄傲计划 经验。 Pride-FTG计划支持的重要培训将影响 代表性不足和残疾的科学家实现了成功的生物医学研究职业。