PRIDE-Functional and Applied Genomics of Blood Disorders

PRIDE-血液疾病的功能和应用基因组学

• 批准号: 8145262
• 负责人: Betty Sue Pace
• 金额: $ 35万
• 依托单位: AUGUSTA UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-09-20 至 2014-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8145262
• 关键词: Address; Applications Grants; Area; Behavioral Sciences; Biomedical Research; Blood; Clinical Research Protocols; Collaborations; Complement; Country; Development; Disabled Persons; Educational Curriculum; Educational process of instructing; Educational workshop; Ensure; Environment; Equilibrium; Faculty; Fostering; Funding; Genomics; Goals; Grant; Health; Heart; Heart Diseases; Hematological Disease; Individual; Institutes; Institution; Knowledge; Learning; Lung; Lung diseases; Mentors; Mentorship; Minority; Morbidity - disease rate; National Heart, Lung, and Blood Institute; Outcome; Population; Private Sector; Program Evaluation; Public Health; Public Sector; Recruitment Activity; Reporting; Research; Research Personnel; Research Priority; Research Project Grants; Research Technics; Research Training; Scientist; Sleep Disorders; Testing; Texas; Training; Training Programs; Training Technics; Universities; Visit; Writing; abstracting; base; career; design; experience; functional genomics; health disparity; improved; interest; mortality; multidisciplinary; programs; public health relevance; skills; skills training

DESCRIPTION (provided by applicant): Project Summary/Abstract: Reports from the private and public sectors provide strong evidence that diversity remains an important challenge in biomedical and behavioral science research programs. To address these issues a Summer Institute Program to Increase Diversity (SIPID)-Functional Genomics of Blood Disorders was funded in 2006 by the National Heart Lung Blood Institute (NHLBI) at the University of Texas at Dallas. We recruited 25 junior faculty mentees who were assigned mentors from a pool of leading investigators in their area of research focus. We taught mentees diverse topics and hands-on bench research and grantsmanship skills. Program evaluations suggest the SIPID program will achieve its primary goal of aiding mentees in obtaining independent grant funding within two years of program completion. We propose to continue this mentored training program to improve the recruitment and retention of underrepresented and disabled faculty in health-related careers. We will establish a Program to Increase Diversity Among Individuals Engaged in Health-Related Research (PRIDE)-Functional and Applied Genomics of Blood Disorders to complete the following aims. Aim 1 (PRIDE 1): In collaboration with the Coordination Core, Mentorship Committees will be established and long-term partnerships developed based on the research interests of mentees and expertise of mentors. A multidisciplinary didactic curriculum related to functional and applied genomics research, grant writing skills and hands-on-bench research techniques will be designed to increase the knowledge and skills of mentees. Aim 2 (Mentoring and Networking Activity): The continued development of the mentor- mentee relationship will be fostered by regular contact with the Mentoring Committee throughout the year. A mid-year visit to the mentor's institution will be sponsored to refine the mentee's research project, grant writing skills, career planning, and additional bench training techniques. Aim 3 (PRIDE 2): PRIDE mentees will continue to develop grantsmanship skills and refine their research projects in order to submit a grant application to acquire NHLBI-sponsored funding. The need for a diverse workforce permeates all aspects of the nation's public health-related research efforts. The PRIDE initiative will fund summer institutes to enable junior faculty to further develop their research skills and knowledge in order to increase the number of underrepresented and disabled scientists in biomedical research careers. Because underrepresented individuals suffer a disproportionate burden of morbidity and mortality associated with heart, lung, blood, and sleep disorders, there is a critical need to increase the number of investigators conducting research on health disparities in this area. PUBLIC HEALTH RELEVANCE: Project Narrative: Currently there exists a growing disparity in the number of minority scientists engaged in biomedical research. Mentoring and training are essential to the retention and recruitment of underrepresented and disabled faculty. The PRIDE-Functional and Applied Genomics of Blood Disorders Summer Institute at the University of Texas at Dallas (UTD) will address these challenges by establishing mentor-mentee partnerships based on common research interests. In addition, the program will provide the mentees with research experiences in functional and applied genomics, develop grantsmanship skills, develop specific research projects, and improve their long-term fundability. The UTD-PRIDE program will strategically complement the efforts of the National Heart Lung and Blood Institute to promote and diversify the country's biomedical workforce.

描述（申请人提供）：项目摘要/摘要：来自私人和公共部门的报告提供了有力的证据，表明多样性在生物医学和行为科学研究计划中仍然是一个重要的挑战。为了解决这些问题，夏季研究所计划增加了多样性（SIPID）的血液疾病功能基因组学，由德克萨斯大学达拉斯大学的国家心脏肺血液研究所（NHLBI）于2006年资助。我们招募了25名初级教师导师，他们被从其研究重点领域的主要调查员群中分配给了导师。我们教导了受训者的多样化主题和动手替补席研究和授予技巧。计划评估表明，SIPID计划将实现其主要目标，以帮助训练者在计划完成的两年内获得独立的赠款资金。我们建议继续这项受过指导的培训计划，以改善与健康相关职业中代表性不足和残疾教师的招聘和保留。我们将建立一个计划以增加多样性 在从事与健康有关的研究（PRIDE）功能和应用基因组学的个人中，以完成以下目标。 目标1（骄傲1）：与协调核心合作，将建立指导委员会，并根据受训者的研究利益和导师的专业知识建立长期合作伙伴关系。与功能和应用基因组研究，授予写作技巧和基础研究技巧有关的多学科教学课程将旨在提高受训者的知识和技能。 AIM 2（指导和网络活动）：全年与指导委员会的定期联系将培养指导人际关系的持续发展。对导师机构的一年中访问将获得赞助，以完善受训者的研究项目，授予写作技巧，职业计划和其他替补训练技巧。 AIM 3（Pride 2）：骄傲的受训者将继续发展赠款技巧并完善其研究项目，以便提交赠款申请以获取NHLBI赞助的资金。 对多样化的劳动力的需求渗透到了美国公共卫生相关的研究工作的各个方面。骄傲倡议将为夏季研究所提供资金，以使初级教师能够进一步发展其研究技能和知识，以增加生物医学研究职业中代表性不足和残疾科学家的数量。由于代表性不足的人承担与心脏，肺，血液和睡眠障碍相关的发病率和死亡率负担不成比例的负担，因此有至关重要的需要增加对该领域健康差异进行研究的研究人员的数量。 公共卫生相关性：项目叙述：目前存在着从事生物医学研究的少数族裔科学家数量的差异。指导和培训对于保留人数不足和残疾教师的保留和招聘至关重要。德克萨斯大学达拉斯分校（UTD）的血液疾病夏季研究所的骄傲和应用基因组学将通过基于共同研究兴趣建立Mentor-Mentor-Mentore伙伴关系来应对这些挑战。 此外，该计划将为受训者提供功能和应用基因组学，发展授予技巧，开发特定的研究项目并提高其长期资金性的研究经验。 UTD自主计划将战略性地补充国家心脏肺和血液研究所在促进和多样化该国生物医学劳动力的努力。