Strategies to Innovate EmeRgENcy Care Clinical trials Network (SIREN) Network - Pittsburgh

创新紧急护理临床试验网络 (SIREN) 网络 - 匹兹堡

• 批准号: 10551627
• 负责人: Clifton W. Callaway
• 金额: $ 39.75万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-07-15 至 2028-01-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10551627
• 关键词: Academic Medical Centers; Acceleration; Accident and Emergency department; Acute; Address; Adoption; Ambulances; Ancillary Study; COVID-19 pandemic; Catheterization; Clinical; Clinical Trials; Clinical Trials Network; Communities; Consent; Coronary; Data; Department of Defense; Development; Distress; Electronic Health Record; Emergency Care; Emergency Medicine; Emergency Situation; Emergency medical service; Emergency research; Emergency treatment; Enrollment; Ensure; Environment; Fellowship; Fostering; Funding; Future; Geography; Health Technology; Home; Hospitals; Informed Consent; Infrastructure; Intensive Care Units; Lead; Leadership; Learning; Life; Location; Mentors; Methods; Nature; Participant; Patient Recruitments; Patients; Phase; Preparation; Procedures; Process; Protocols documentation; Publishing; Research; Research Personnel; Rural; Scientific Advances and Accomplishments; Secure; Site; Structure; Teacher Professional Development; Text Messaging; Time; Training; United States National Institutes of Health; Universities; Work; career; clinical development; community engagement; emergency settings; experience; improved; innovation; mHealth; member; novel; outreach; participant enrollment; recruit; remote consent; screening; skills; success; telepresence; treatment trial

The University of Pittsburgh site for the Strategies to Innovate Emergency Care Clinical Trials Network (SIREN) will continue its leadership as a Hub for recruiting participants into emergency care research. Advancements in acute treatment for time-sensitive and life-threatening conditions requires high quality and rigorous trials. The unexpected nature of emergency conditions sometimes demands that participants enter trials under atypical processes such as an Exception from Informed Consent. Emergency care spans multiple locations including prehospital, emergency department, intensive care unit, and home. An experienced research team will implement pragmatic and successful strategies to accomplish enrollment under all these conditions and in all these settings at multiple sites by addressing the following Aims. 1. Provide administrative structure to rapidly implement and enroll from multiple sites in multiple clinical trials of emergency treatments. 2. Explore strategies to increase recruitment, and consent in emergency treatment trials. 3. Explore strategies to increase quality of emergency care data and to ensure retention of subjects enrolled in emergency settings. 4. Advance participation and training for early career investigators.

匹兹堡大学紧急护理临床试验网络创新策略网站 (SIREN) 将继续发挥其作为紧急护理研究招募参与者中心的领导作用。对时间敏感和危及生命的疾病的急性治疗的进展需要高质量和严格的试验。紧急情况的意外性质有时要求参与者按照非典型程序（例如知情同意例外）进入试验。紧急护理跨越多个地点，包括院前、急诊室、重症监护室和家庭。经验丰富的研究团队将实施务实且成功的策略，通过实现以下目标，在所有这些条件和所有这些环境下在多个地点完成注册。 1. 提供管理结构，以快速实施和从多个地点注册多个紧急治疗临床试验。 2. 探索增加紧急治疗试验招募和同意的策略。 3. 探索提高紧急护理数据质量并确保保留紧急情况下登记受试者的策略。 4. 促进早期职业调查人员的参与和培训。