The effects of maternal borderline personality disorder on toddler theory of mind development

母亲边缘性人格障碍对幼儿心理发展理论的影响

基本信息

批准号：
10460417
负责人：
Salome Vanwoerden
金额：
$ 6.76万
依托单位：
UNIVERSITY OF PITTSBURGH AT PITTSBURGH
依托单位国家：
美国
项目类别：
财政年份：
2021
资助国家：
美国
起止时间：
2021-06-01 至 2023-05-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10460417
关键词：
Active Learning Address Adolescence Adolescent Affective Age Agreement Anger Attention Behavior Behavioral Biological Models Borderline Personality Disorder Caregivers Child Child Behavior Code Data Deceleration Development Diagnosis Disadvantaged Emotional Family Fostering Frequencies Functional disorder Gold Heart Rate Hostility Impairment Individual Intervention Knowledge Lead Learning Life Maternal Behavior Measurement Measures Mediating Mental disorders Mind Modeling Mother-Child Relations Mothers National Institute of Mental Health Nursery Schools Onset of illness Parents Pattern Perception Phase Physiological Physiology Play Preschool Child Prevention Prevention Research Process Psychophysiology Research Research Domain Criteria Risk Risk Behaviors Risk Factors Role Sampling Series Social Processes Strategic Planning Symptoms Testing Time Toddler Training Withdrawal aged analytical method approach behavior base catalyst cost dynamic system early childhood experience falls follow-up high risk improved indexing maladaptive behavior mental state novel offspring prevent response severe mental illness skills social engagement social influence social learning suicidal behavior symptomatology theories

项目摘要

PROJECT SUMMARY/ABSTRACT Theory of mind (ToM) is the ability to perceive and understand mental states in others a nd represents one operationalization of the RDoC construct of Perception and Understanding of Others. ToM is an early emerging mechanism in the development of borderline personality disorder (BPD); individuals with BPD tend to misattribute mental states to others, spurring a cycle of anger dysregulation, interpersonal dysfunction, and suicidal behavior. Aligned with the 2020 NIMH strategic plan, to identify malleable targets for prevention of BPD, it is necessary to study the unfolding of this critical mechanism prior to the onset of symptomatology. The current proposal aims to do so in a high-risk mother-child sample in which mothers have BPD and offspring are 36-48 months old, a critical time for ToM development. Further, this study will elucidate the specific behaviors that mothers with BPD engage in that influence the development of ToM during the preschool period as well as child behaviors involved in this process. ToM undergoes rapid development during the preschool age and is highly susceptible to environmental influence, particularly interactions with caregivers. This proposal details a comprehensive training plan that will enable me to address these questions while building on previous experiences in important ways. First, expanding on my experience studying ToM and related processes in adolescence, I will focus on the developmental trajectory of this construct during the preschool age. Second, I will obtain training in measurement and interpretation of heart rate and RSA as physiological markers of preschooler social engagement with mothers. Third, building on my knowledge of global behavioral coding of mother-adolescent interactions, I will master the use of micro-analytic coding to obtain continuous time-series data of mother and child behavior within interactions. Further, I will learn novel analytic methods for this unique data based on dynamic systems modeling. The specific aims of this study are to 1) Determine whether two forms of maladaptive maternal behaviors--hostility and inaccurate mental state attribution--are observed more often among mothers with BPD compared to those with no psychiatric disorder; 2) Evaluate how preschooler social engagement with mothers (i.e., approach and withdrawal behaviors as well as heart rate and RSA) is influenced by these maternal behaviors; and 3) Test the effect of identified maternal behaviors on the trajectory of ToM development over the course of one year in preschoolers. The central hypothesis of this proposal is that maternal BPD is associated with maladaptive behaviors directed toward their children. These behaviors lead to a pattern of dysfunctional social engagement by preschoolers (decreased approach and increased withdrawal behavior toward mother during as well as heart rate deceleration and RSA withdrawal), which further inhibits their ToM development during this critical phase. By identifying risk factors associated with ToM, families at risk can be targeted for specific interventions focused on improving the quality of mother-child interactions, which may have the effect of preventing BPD onset in offspring.

项目摘要/摘要心理理论（汤姆）是在他人中感知和理解心理状态的能力，而不是一个 RDOC构造的感知和对他人理解的操作。汤姆是一个早期的边缘人格障碍发展的机制（BPD）；患有BPD的人倾向于将精神状态错误地归因于他人，激发了愤怒失调，人际功能障碍和自杀行为。与2020年NIMH战略计划保持一致，以确定可延展的预防BPD的目标在症状发作之前，有必要研究这种关键机制的发展。电流提案的目的是在母亲的高风险母子样本中这样做，在该样本中，母亲有BPD，后代为36-48 几个月大，这是汤姆发展的关键时刻。此外，这项研究将阐明 BPD的母亲从事学龄前时期的汤姆和孩子的发展此过程中涉及的行为。汤姆在学龄前经历了快速发展，并且很高容易受到环境影响，尤其是与看护人的互动。该建议详细介绍了全面的培训计划，这将使我能够在以前的建设中解决这些问题以重要方式的经验。首先，扩展我研究汤姆和相关过程的经验青春期，我将重点介绍学龄前年龄期间这种结构的发展轨迹。第二，我将获得对心率和RSA的测量和解释作为生理标记的培训学龄前儿童与母亲的社交参与。第三，基于我对全球行为编码的了解母亲互动，我将掌握微分析编码的使用以获得连续的时间序列互动中母亲和儿童行为的数据。此外，我将学习这种独特的新颖分析方法基于动态系统建模的数据。这项研究的具体目的是1）确定是否两种形式适应不良的孕产妇行为 - 托管和精神状态不准确 - 经常观察到与没有精神疾病的母亲相比，有BPD的母亲； 2）评估学龄前儿童如何社交与母亲的互动（即接近和戒断行为以及心率和RSA）受到影响通过这些孕产妇行为； 3）测试已鉴定的孕产妇行为对汤姆轨迹的影响在学龄前儿童的一年中的发展。该提议的中心假设是母亲 BPD与针对孩子的不良适应行为有关。这些行为导致了模式学龄前儿童的社会参与功能失调（方法减少和提高行为增加对母亲以及心率减速和RSA提取），这进一步抑制了他们的汤姆在这个关键阶段的发展。通过确定与汤姆相关的风险因素，处于危险的家庭可以是针对特定干预措施的目的是提高母子互动的质量，这可能具有防止BPD在后代中发作的影响。

项目成果

期刊论文数量（7）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Maternal invalidation and child RSA reactivity to frustration interact to predict teacher-reported aggression among at-risk preschoolers.

DOI：
10.1017/s0033291722003713
发表时间：
2023-10
期刊：
Psychological medicine
影响因子：
6.9
作者：
Byrd AL;Frigoletto OA;Vine V;Vanwoerden S;Jennings JR;Zalewski M;Stepp SD
通讯作者：
Stepp SD

Are We Thinking about the Same Disorder? A Trifactor Model Approach to Understand Parents' and Their Adolescents' Reports of Borderline Personality Pathology.

我们正在考虑同样的疾病吗？

DOI：
10.1080/00223891.2022.2039165
发表时间：
2023
期刊：
Journal of personality assessment
影响因子：
3.4
作者：
Vanwoerden,Salome;McLaren,Veronica;Stepp,StephanieD;Sharp,Carla
通讯作者：
Sharp,Carla

Sampling methods in personality pathology research: Some data and recommendations.

人格病理学研究中的抽样方法：一些数据和建议。

DOI：
10.1037/per0000593
发表时间：
2023
期刊：
Personality disorders
影响因子：
0
作者：
Vanwoerden,Salome;Chandler,Jesse;Cano,Kiana;Mehta,Paras;Pilkonis,PaulA;Sharp,Carla
通讯作者：
Sharp,Carla

The role of youths' cardiac autonomic balance and parental responses to youth emotion in vulnerability to borderline personality disorder development.

青少年心脏自主平衡和父母对青少年情绪的反应在易患边缘性人格障碍发展中的作用。