Peer Support for Lowering Blood Pressure among Adolescents: A Pilot, Randomized Controlled Trial

同伴支持降低青少年血压：一项随机对照试验

• 批准号: 10508121
• 负责人: Shakia Tranece Hardy
• 金额: $ 14.61万
• 依托单位: UNIVERSITY OF ALABAMA AT BIRMINGHAM
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-01 至 2027-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10508121
• 关键词: 17 year old; Academic skills; Academy; Active Learning; Address; Adherence; Adolescence; Adolescent; Adoption; Adult; Affect; Alabama; American; Behavior; Black race; Blood Pressure; Body Weight decreased; Cardiovascular Diseases; Cardiovascular system; Childhood; Church; Clinic; Clinical; Cluster randomized trial; Communities; Counseling; DASH diet; Data; Development; Diastolic blood pressure; Dietary Practices; Doctor of Philosophy; Education; Educational Curriculum; Epidemiology; Evaluation; Face; Feedback; Focus Groups; Food; Funding; Goals; Grant; Guidelines; Health behavior; Health education; Healthy Eating; High Prevalence; Hypertension; Individual; Intervention; Interview; K-Series Research Career Programs; Lead; Leadership; Life; Life Style; Life Style Modification; Medicine; Mentors; Mentorship; Methods; Morbidity - disease rate; North Carolina; Obesity; Parents; Participant; Pediatrics; Persons; Physical activity; Pilot Projects; Population Sciences; Positioning Attribute; Preventive Medicine; Principal Investigator; Process Measure; Protocols documentation; Publishing; Randomized Controlled Trials; Reach Effectiveness Adoption Implementation and Maintenance; Recommendation; Reduce health disparities; Research; Research Personnel; Rural; Rural Community; Scientist; Self Efficacy; Self Management; Site; Structure; Surveys; Testing; Time; Training; Travel; Universities; acceptability and feasibility; base; behavior change; behavior change wheel; blood pressure elevation; blood pressure reduction; cardiovascular disorder epidemiology; cardiovascular disorder risk; cardiovascular health; career development; contextual factors; design; didactic education; dietary; effective intervention; effectiveness testing; effectiveness trial; experience; feasibility testing; future implementation; health care availability; health disparity; health equity; healthy lifestyle; implementation intervention; implementation science; improved; intervention delivery; mortality; patient-clinician communication; payment; peer; peer support; pilot test; preempt; professor; programs; racial disparity; recruit; research and development; rural environment; rural residence; satisfaction; skills; social epidemiology; social health determinants; success; tenure track; theories; therapy development; uptake

ABSTRACT This K01 career development proposal was developed to support Dr. Shakia Hardy, a tenure track Assistant Professor in the Department of Epidemiology at the University of Alabama at Birmingham (UAB), in her path towards becoming an independent researcher. The Candidate earned her PhD in Epidemiology in 2017 from the University of North Carolina at Chapel Hill and has a strong record of published research in the fields of cardiovascular and social epidemiology. Her goal is to integrate her epidemiology skills with implementation science to develop an independent research program at the intersection of implementation and population science. Dr. Hardy’s research aims to reduce health disparities in cardiovascular disease through the modification of lifestyle behaviors that contribute to increased blood pressure in early life. Training: To accomplish her overall goal, Dr. Hardy has proposed an intensive mentored research plan that includes didactic education, and experiential learning in 1) intervention development, 2) implementation science for intervention delivery and evaluation, 3) design and conduct of randomized controlled trials, and 4) leadership skills for academic scientists. Mentorship: An interdisciplinary team of renowned scholars will mentor Dr. Hardy and provide ongoing guidance as she transitions to independence. Her mentoring team includes a Primary Mentor, Dr. Andrea Cherrington (Department of Preventive Medicine, UAB), co-Mentors, Dr. Paul Muntner (Department of Epidemiology, UAB), Dr. Nathalie Moise (Department of Medicine, Columbia University) and Dr. Daniel Feig (Department of Medicine, UAB) and two content advisors at UAB. Each of these mentors are fully committed to this project and to Dr. Hardy’s success. Research: The prevalence of high BP, defined as systolic BP (SBP) ≥120 mm Hg or diastolic BP (DBP) ≥80 mm Hg, is two-times higher (20% versus 10%) among Black versus white adolescents 13-17 years of age in the US. The availability of lifestyle behavior counseling in a clinical setting to lower BP is limited in rural communities due to long travel distances to access healthcare, limited funds for co-payments, and ineffective provider-patient communication. The proposed K01 addresses this gap by developing and testing the feasibility and acceptability of a peer support intervention to lower BP among rural Black adolescents with high BP. First, Dr. Hardy will identify aspects of the rural environment that present barriers to lifestyle behavior change. Next, using the behavior change wheel for intervention development, she will develop and pilot test a peer support intervention devised to address these barriers. The successful completion of this project will lead to an R01 grant submission to test the effectiveness of this peer support intervention in a multi-site cluster-randomized trial and allow Dr. Hardy to become an independent investigator contributing to health equity among adolescents, where lifestyle behavior change could preempt the development of racial disparities in BP and cardiovascular morbidity and mortality.

抽象的 这项K01职业发展计划的制定是为了支持终身助理助理Shakia Hardy博士 阿拉巴马大学伯明翰大学（UAB）流行病学系教授 成为一名独立研究员。候选人于2017年获得了她的流行病学博士学位 北卡罗来纳大学教堂山分校，在该领域有很强的发表研究记录 心血管和社会流行病学。她的目标是将她的流行病学技能与实施相结合 在实施与人口的交集中制定独立研究计划的科学 科学。哈迪博士的研究旨在通过通过 修改生活方式行为会导致早期血压升高。培训：进行 实现她的整体目标，哈迪博士提出了一项严格修补的研究计划，其中包括 教育教育，并在1）干预开发中经历了学习，2）实施科学 干预交付和评估，3）设计和进行随机对照试验，4）领导 学术科学家的技能。指导：著名学者的跨学科团队将指导博士。 在过渡到独立时，耐心并提供持续的指导。她的心理团队包括 主要导师Andrea Cherrington博士（UAB预防医学系），合伙人Paul博士 Muntner（UAB流行病学系），Nathalie Moise博士（哥伦比亚医学系 大学）和UAB的两名内容顾问Daniel Feig（医学系）。每个 这些导师完全致力于这个项目以及哈迪博士的成功。研究：患病率 高BP，定义为收缩BP（SBP）≥120mm Hg或舒张压BP（DBP）≥80mm Hg，高度高两倍 在美国，黑人与白人青少年中的13-17岁的黑人青少年中（20％v ves 10％）。可用性 由于长途旅行，在农村社区的临床环境中，在临床环境中的生活方式行为咨询受到限制 获得医疗保健的距离，共同付款的有限资金以及无效的提供者与患者交流。 提出的K01通过开发和测试同伴的可行性和可接受性来解决这一差距 支持较高BP的黑色黑色青少年中降低BP的干预措施。首先，哈迪博士将确定 粗糙环境的各个方面，呈现出生活方式行为的障碍。接下来，使用行为 更改干预措施开发的轮子，她将开发和试点测试同行支持干预措施 解决这些障碍。该项目的成功完成将导致R01赠款提交进行测试 此同行支持干预措施在多站点集群随机试验中的有效性，并允许Hardy博士能够 成为一名独立的研究者，为青少年的健康公平做出贡献，生活方式行为 变革可以抢占BP和心血管发病率和死亡率中种族分布的发展。