Peer Support for Lowering Blood Pressure among Adolescents: A Pilot, Randomized Controlled Trial

同伴支持降低青少年血压：一项随机对照试验

• 批准号: 10508121
• 负责人: Shakia Tranece Hardy
• 金额: $ 14.61万
• 依托单位: UNIVERSITY OF ALABAMA AT BIRMINGHAM
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-01 至 2027-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10508121
• 关键词: 17 year old; Academic skills; Academy; Active Learning; Address; Adherence; Adolescence; Adolescent; Adoption; Adult; Affect; Alabama; American; Behavior; Black race; Blood Pressure; Body Weight decreased; Cardiovascular Diseases; Cardiovascular system; Childhood; Church; Clinic; Clinical; Cluster randomized trial; Communities; Counseling; DASH diet; Data; Development; Diastolic blood pressure; Dietary Practices; Doctor of Philosophy; Education; Educational Curriculum; Epidemiology; Evaluation; Face; Feedback; Focus Groups; Food; Funding; Goals; Grant; Guidelines; Health behavior; Health education; Healthy Eating; High Prevalence; Hypertension; Individual; Intervention; Interview; K-Series Research Career Programs; Lead; Leadership; Life; Life Style; Life Style Modification; Medicine; Mentors; Mentorship; Methods; Morbidity - disease rate; North Carolina; Obesity; Parents; Participant; Pediatrics; Persons; Physical activity; Pilot Projects; Population Sciences; Positioning Attribute; Preventive Medicine; Principal Investigator; Process Measure; Protocols documentation; Publishing; Randomized Controlled Trials; Reach Effectiveness Adoption Implementation and Maintenance; Recommendation; Reduce health disparities; Research; Research Personnel; Rural; Rural Community; Scientist; Self Efficacy; Self Management; Site; Structure; Surveys; Testing; Time; Training; Travel; Universities; acceptability and feasibility; base; behavior change; behavior change wheel; blood pressure elevation; blood pressure reduction; cardiovascular disorder epidemiology; cardiovascular disorder risk; cardiovascular health; career development; contextual factors; design; didactic education; dietary; effective intervention; effectiveness testing; effectiveness trial; experience; feasibility testing; future implementation; health care availability; health disparity; health equity; healthy lifestyle; implementation intervention; implementation science; improved; intervention delivery; mortality; patient-clinician communication; payment; peer; peer support; pilot test; preempt; professor; programs; racial disparity; recruit; research and development; rural environment; rural residence; satisfaction; skills; social epidemiology; social health determinants; success; tenure track; theories; therapy development; uptake

ABSTRACT This K01 career development proposal was developed to support Dr. Shakia Hardy, a tenure track Assistant Professor in the Department of Epidemiology at the University of Alabama at Birmingham (UAB), in her path towards becoming an independent researcher. The Candidate earned her PhD in Epidemiology in 2017 from the University of North Carolina at Chapel Hill and has a strong record of published research in the fields of cardiovascular and social epidemiology. Her goal is to integrate her epidemiology skills with implementation science to develop an independent research program at the intersection of implementation and population science. Dr. Hardy’s research aims to reduce health disparities in cardiovascular disease through the modification of lifestyle behaviors that contribute to increased blood pressure in early life. Training: To accomplish her overall goal, Dr. Hardy has proposed an intensive mentored research plan that includes didactic education, and experiential learning in 1) intervention development, 2) implementation science for intervention delivery and evaluation, 3) design and conduct of randomized controlled trials, and 4) leadership skills for academic scientists. Mentorship: An interdisciplinary team of renowned scholars will mentor Dr. Hardy and provide ongoing guidance as she transitions to independence. Her mentoring team includes a Primary Mentor, Dr. Andrea Cherrington (Department of Preventive Medicine, UAB), co-Mentors, Dr. Paul Muntner (Department of Epidemiology, UAB), Dr. Nathalie Moise (Department of Medicine, Columbia University) and Dr. Daniel Feig (Department of Medicine, UAB) and two content advisors at UAB. Each of these mentors are fully committed to this project and to Dr. Hardy’s success. Research: The prevalence of high BP, defined as systolic BP (SBP) ≥120 mm Hg or diastolic BP (DBP) ≥80 mm Hg, is two-times higher (20% versus 10%) among Black versus white adolescents 13-17 years of age in the US. The availability of lifestyle behavior counseling in a clinical setting to lower BP is limited in rural communities due to long travel distances to access healthcare, limited funds for co-payments, and ineffective provider-patient communication. The proposed K01 addresses this gap by developing and testing the feasibility and acceptability of a peer support intervention to lower BP among rural Black adolescents with high BP. First, Dr. Hardy will identify aspects of the rural environment that present barriers to lifestyle behavior change. Next, using the behavior change wheel for intervention development, she will develop and pilot test a peer support intervention devised to address these barriers. The successful completion of this project will lead to an R01 grant submission to test the effectiveness of this peer support intervention in a multi-site cluster-randomized trial and allow Dr. Hardy to become an independent investigator contributing to health equity among adolescents, where lifestyle behavior change could preempt the development of racial disparities in BP and cardiovascular morbidity and mortality.

抽象的 制定此 K01 职业发展提案是为了支持终身教授助理 Shakia Hardy 博士 阿拉巴马大学伯明翰分校 (UAB) 流行病学系教授 该候选人于 2017 年获得流行病学博士学位。 北卡罗来纳大学教堂山分校，在以下领域发表的研究成果丰硕 她的目标是将她的流行病学技能与实施相结合。 科学在实施和人口交叉点制定独立研究计划 哈迪博士的研究旨在通过以下方式减少心血管疾病的健康差异。 改变导致生命早期血压升高的生活方式： 训练。 为了实现她的总体目标，哈迪博士提出了一项深入指导的研究计划，其中包括 教学教育和体验式学习 1) 干预开发，2) 实施科学 干预措施的实施和评估，3) 随机对照试验的设计和实施，以及 4) 领导力 学术科学家的技能指导：由著名学者组成的跨学科团队将指导博士。 Hardy 并在她过渡到独立的过程中提供持续的指导。 主要导师 Andrea Cherrington 博士（UAB 预防医学系），共同导师 Paul 博士 Muntner（UAB 流行病学系）、Nathalie Moise 博士（哥伦比亚医学系） 大学）和 Daniel Feig 博士（UAB 医学系）以及 UAB 的两名内容顾问。 这些导师完全致力于这个项目和哈迪博士的研究：流行。 高血压定义为收缩压 (SBP) ≥120 毫米汞柱或舒张压 (DBP) ≥80 毫米汞柱，是其两倍 美国 13-17 岁黑人青少年与白人青少年的比例（20% 与 10%）。 由于长途旅行，在临床环境中降低血压的生活方式行为咨询在农村社区受到限制 获得医疗保健的距离、共同支付资金有限以及提供者与患者的沟通效率低下。 拟议的 K01 通过开发和测试同行的可行性和可接受性来解决这一差距 哈迪博士将首先确定降低高血压的农村黑人青少年血压的干预措施。 农村环境对生活方式行为改变构成障碍的方面接下来是使用行为。 改变干预发展的轮子，她将开发并试点测试设计的同伴支持干预 为了解决这些障碍，该项目的成功完成将导致 R01 拨款提交以进行测试。 同行支持干预在多中心随机试验中的有效性，并允许 Hardy 博士 成为一名独立调查员，为青少年的公平做出贡献，其中生活方式行为 改变可能会阻止血压、心血管发病率和死亡率方面种族差异的发展。