Laboratory Sciences Core

实验室科学核心

• 批准号: 10458282
• 负责人: Savita Pahwa
• 金额: $ 39.21万
• 依托单位: UNIVERSITY OF MIAMI SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-11-01 至 2027-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10458282
• 关键词: AIDS/HIV problem; Acquired Immunodeficiency Syndrome; Address; Administrative Supplement; Adolescence; Advisory Committees; Affect; Applications Grants; Area; Back; Benchmarking; Biological Assay; COVID-19; COVID-19 Prevention Network; COVID-19 pandemic; Cancer Center; Cells; Charge; Child; Childhood; Clinical; Clinical Sciences; Cohort Studies; Collaborations; Communicable Diseases; Consultations; Data; Data Science; Development; Educational workshop; Emerging Communicable Diseases; Ensure; Epidemic; Equipment; Exercise; Florida; Funding; Generations; Genomics; Goals; HIV; HIV Vaccine Trials Network; Immunology; Individual; Institutes; Institution; Interest Group; International; International Maternal Pediatric Adolescent AIDS Clinical Trials; Irrigation; Laboratories; Letters; Life; Mentorship; Microbiology; Needs Assessment; Periodicity; Policies; Procedures; Publications; Research; Research Activity; Research Design; Research Institute; Research Personnel; Research Priority; Research Project Grants; Research Support; Resource Sharing; Resources; Science; Scientific Advances and Accomplishments; Services; Sexual Health; Students; Techniques; Technology; Training; Translational Research; United States National Institutes of Health; Universities; Update; Virus; Woman; acronyms; assay development; base; biobank; biobehavior; cancer genomics; cervicovaginal; collaboratory; coronavirus disease; data portal; expectation; faculty support; improved; innovation; interest; lectures; meetings; microbiome; new technology; novel; perinatal HIV; programs; quality assurance; success; symposium; synergism; undergraduate student; virology; working group

Project Summary/Abstract (Laboratory Sciences Core (Core D)) In this 4th renewal application of the Miami CFAR, Drs. Savita Pahwa as Director and Sion Williams as Co- Director of the Laboratory Sciences Core (Core D) propose a centralized resource for immunology, genomics and virology with opportunities to stimulate novel HIV/AIDS research towards notable benchmarks of success. Since its inception, the goal of the Miami CFAR has been to evolve to keep pace with the changing needs of the epidemic to address important questions in HIV/AIDS. Accordingly, Core D’s strategy has been to maximize Core resources by leveraging institutional and external resources in order to be at the forefront of HIV/AIDS research. In the current cycle (2017-2022), Core D has made tremendous progress, energized by new projects, new technologies and new equipment. We remain cognizant of expectations from the users through periodic needs assessment exercises, adequate Core utilization to support for projects of our funded research base (FRB) and pilot awardees, mentorship to students and junior faculty, support research presentations at conferences and establish linkages with other CFARs to maximize our capabilities for alignment with NIH research priorities and advances in the field. For the next funding cycle, our goal is to provide needed services to our investigator base while ensuring access to state-of-the-art technologies that drive innovation and help to address key scientific questions in HIV/AIDS. Our specific Aims are: Aim 1. Serve as a one stop shop, that allows investigators to easily access Immunology, Virology and Genomics services to meet both needs for high demand assays as well as specialized assays that require dedicated expertise. Aim 2. Provide consultation, training and technical assistance for investigators at all levels (from undergraduate students to established investigators) to meet their needs for study design, generation of preliminary data and data for publications, and to disseminate information about scientific advances in the field through special lectures and workshops in collaboration with the Sylvester Cancer Center, Clinical and Translational Science Institute (CTSI) , and Departments of Microbiology and Immunology, and Infectious Diseases Division at the University of Miami (UM). Aim 3. Promote synergies in UM and provide research support/collaborations across Florida, NIH funded Networks and Programs by: a) Interaction with Cores, Scientific Areas of Interest (SIG), Scientific Working Groups (SWG) and CFAR membership at large, through participation in group discussions/meetings, collaborative research projects with clinical/biobehavioral science investigators; b) Advancing the CFAR laboratory expertise through leveraging non-CFAR resources and inter-CFAR interactions, and c) Responding to emergent institutional and societal priorities such as COVID-19 for laboratory support, and to develop techniques to promote research in COVID as it affects HIV; d) Offer CFAR expertise to support HIV Network activities and HIV research outside UM. Aim 4. Develop and abide by policies and procedures for the Core in compliance with Core A directives and guidance.

项目摘要/摘要（实验室科学核心（核心 D）） 在迈阿密 CFAR 的第四次续签申请中，萨维塔·帕瓦 (Savita Pahwa) 博士担任主任，西恩·威廉姆斯 (Sion Williams) 担任联合- 实验室科学核心（核心 D）主任提出了免疫学、基因组学的集中资源 和病毒学，有机会刺激新的艾滋病毒/艾滋病研究达到显着的成功基准。 自成立以来，迈阿密 CFAR 的目标就是不断发展，以跟上不断变化的需求 因此，Core D 的战略是最大限度地解决艾滋病毒/艾滋病方面的重要问题。 利用机构和外部资源的核心资源，以便处于艾滋病毒/艾滋病的最前沿 在当前周期（2017-2022）中，核心 D 在新项目的推动下取得了巨大进展， 我们定期了解用户的期望。 需求评估练习，充分利用核心来支持我们资助的研究基地的项目 （FRB）和试点获奖者，对学生和初级教师的指导，支持研究报告 会议并与其他 CFAR 建立联系，以最大限度地提高我们与 NIH 保持一致的能力 该领域的研究重点和进展 对于下一个资助周期，我们的目标是提供所需的服务。 访问我们的研究人员基地，同时获得最先进的技术，推动创新并帮助 解决艾滋病毒/艾滋病的关键科学问题 我们的具体目标是： 目标 1. 提供一站式服务。 使研究人员能够轻松获得免疫学、病毒学和基因组学服务，以满足高水平的需求 目标 2. 提供咨询、 为各级调查人员（从本科生到已建立的机构）提供培训和技术援助 研究人员）以满足他们对研究设计、生成初步数据和出版物数据的需求，以及 通过特别讲座和研讨会传播有关该领域科学进展的信息 与西尔维斯特癌症中心、临床和转化科学研究所 (CTSI) 合作，以及 迈阿密大学 (UM) 微生物学和免疫学系以及传染病科。 目标 3. 促进 UM 的协同作用，并在 NIH 资助的佛罗里达州提供研究支持/合作 网络和计划：a) 与核心、科学兴趣领域 (SIG)、科学工作的互动 通过参与小组讨论/会议，团体 (SWG) 和 CFAR 全体会员， 与临床/生物行为科学研究人员的合作研究项目；b) 推进 CFAR； 通过利用非 CFAR 资源和 CFAR 之间的相互作用来获得实验室专业知识，以及 c) 响应 紧急的机构和社会优先事项，例如用于实验室支持的 COVID-19，并制定 促进 COVID 影响 HIV 的研究的技术； d) 提供 CFAR 专业知识以支持 HIV 网络 目标 4. 制定并遵守 UM 核心政策和程序。 遵守核心 A 指令和指南。