Population Sciences

人口科学

基本信息

批准号：
10411083
负责人：
ESTHER M. JOHN
金额：
$ 6.67万
依托单位：
STANFORD UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2007
资助国家：
美国
起止时间：
2007-06-04 至 2027-05-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10411083
关键词：
Address Age Applications Grants Behavioral Behavioral Sciences Big Data Bioinformatics Body Composition Breast Breast Cancer Genetics COVID-19 complications Cancer Burden Cancer Etiology Cancer Patient Caregivers Catchment Area Clinical Clinical Sciences Collaborations Collection Colon Communities Community Health Community Outreach Computerized Medical Record Data Set Detection Diagnosis Diet Disease Progression Effectiveness Ensure Environmental Exposure Epidemiology Ethnic Origin Etiology Faculty Family Cancer History Funding Future Gender Genes Genetic Genetic Risk Geography Goals Grant Guidelines Health Health Policy Health Services Incidence Institutes International Intervention Intervention Studies Intervention Trial Journals K-Series Research Career Programs Lead Leadership Legal Life Cycle Stages Life Style Liver Longevity Lung Machine Learning Malignant Neoplasms Malignant neoplasm of lung Manuscripts Medicare Mentors Metabolic Methods Minor Mobile Health Application Modeling Molecular Morbidity - disease rate NCI-Designated Cancer Center Neoplasm Metastasis Obesity Observational Study Outcome Palliative Care Pancreatic Lymphoma Pathogenicity Patients Peer Review Physical activity Population Population Heterogeneity Population Sciences Practice Guidelines Prevention Prevention Research Prognostic Factor Prostate Public Health Publishing Quality of life Race Rectum Recurrence Research Research Personnel Research Priority Resource Sharing Risk Factors Risk Reduction Sales Scientist Screening for cancer Second Primary Cancers Sexual and Gender Minorities Sleep Socioeconomic Status Stress Symptoms Testing Tobacco Tobacco use Training Training Programs Translational Research Treatment Factor United States National Institutes of Health Variant adverse outcome associated symptom behavior change brca gene cancer care cancer health disparity cancer prevention cancer risk cancer therapy clinical care clinical decision-making clinical development clinical practice community engagement computed tomography screening cost effective data mining data resource efficacy testing end of life end of life care gender minority health genetic epidemiology genetic risk assessment genetic testing health disparity health equity high risk population implementation science improved improved outcome innovation lifestyle intervention member mortality multidisciplinary new technology next generation nicotine use novel peer support personalized approach pre-clinical programs recruit risk prediction risk prediction model screening sedentary sex social determinants social health determinants survivorship tobacco control tobacco products tobacco user treatment response working group

项目摘要

PROJECT SUMMARY The goal of the Population Sciences Program (PS) of the Stanford Cancer Institute (SCI) is to conduct high- impact transdisciplinary and translational research across the cancer continuum aimed at improving detection through screening, reducing cancer incidence, morbidity and mortality, and improving cancer outcomes. The PS achieves this goal by promoting and facilitating innovative multidisciplinary observational and interventional research on cancer that will impact public health and guide clinical practice and health policy. PS members are nationally and internationally recognized clinical and population scientists with a broad range of unique strengths in epidemiology, genetics, quantitative modeling, bioinformatics, use of novel technologies, behavioral science, lifestyle (physical activity, diet, tobacco control, sleep), and clinical and palliative care interventional trials, and community health and prevention research. The program’s overarching research priorities include reducing the cancer burden and disparities (by age, sex and gender, race and ethnicity, socioeconomic status, geography, and other social determinants of health) in the highly diverse population of SCI’s catchment area. PS members’ research addresses the following Specific Aims: Aim 1: Conduct research on cancer etiology, risk prediction, screening, and genetic testing; Aim 2: Investigate the impact of cancer treatment and prognostic factors on outcomes; and Aim 3: Conduct intervention research to reduce cancer risks and improve outcomes. The PS has 39 members, of whom 31 are supported by peer-reviewed funding totaling $14.0M, including $7.4M from the NCI, $5.0M other cancer-relevant NIH support, and $1.6M from other peer-reviewed support. During the current funding period, PS members published 1,130 peer-reviewed manuscripts. Of these, 22% are intra- programmatic, 23% are inter-programmatic, 96% are multi-institutional, and 18% are in journals with an impact factor of 10 or higher. Support from the SCI has been instrumental in promoting both intra- and inter- programmatic collaborations of PS members, recruiting new faculty members, and enabling preliminary research through innovation grants that lead to externally funded projects. PS members also strive to train the next generation of cancer prevention researchers. In the future, the PS will further expand and focus on research in genetic risk profiling and assessment, outcomes and survivorship research across the life course, cancer in sexual and gender minorities, and health services and implementation science, and will develop and submit a T32 training grant in genetic epidemiology and population sciences.

项目摘要斯坦福癌症研究所（SCI）的人口科学计划（PS）的目标是影响针对印度检测的癌症连续体的跨学科和翻译研究通过筛查，降低癌症的发病率，病态和死亡率以及PS的即兴结局。通过促进和促进创新的多学科观察和国际来实现这一目标对健康和指导临床实践政策的癌症的研究具有广泛独特优势的国家和国际公认的临床和人口科学家在流行病学，遗传学，定量建模，生物信息学，新技术的使用，行为科学，生活方式（物理活动，饮食，烟草控制，睡眠）以及临床和姑息治疗介入试验，社区健康与预防研究。癌症负担和差异（按年龄，性别和性别，种族和种族，社会经济地位，地理，地理，以及在散点区高度多样化的健康决定因素）。 PS成员的研究针对以下特定目的：目标1：对癌症的研究，风险进行研究预测，筛查和基因检测；目标2：研究癌症治疗的影响结果的因素； 3：进行干预研究以减少癌症的风险并改善预后。有39名成员，其中31名由同行评审的资金总额为1400万美元，其中包括740万美元在NCI中，其他与癌症的NIH支持500万美元，在其他评审期间获得160万美元。当前的资金期，PS成员发布了1,130个同行评审的手稿。程序化，23％是程序间的，有96％是多工资，有18％的期刊在具有影响力的期刊中 SCI的10倍或高度的因子有助于促进内部和 PS成员的程序合作，招募新教师并实现预后研究通过创新赠款，导致外部资助的项目。预防癌症的研究人员将来。遗传风险分析和评估，成果和生存研究的结果和生存研究，癌症性和性别少数群体以及卫生服务和隐含科学，并将发展和提交 T32遗传增长和人口科学中的培训补助金。