Cancer Research Education, Advancement, Training and Empowerment (CREATE) in the Pacific

太平洋地区的癌症研究教育、进步、培训和赋权 (CREATE)

• 批准号: 10226218
• 负责人: Joseph Keawe'aimoku Kaholokula
• 金额: $ 27.13万
• 依托单位: UNIVERSITY OF HAWAII AT MANOA
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-08-01 至 2025-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10226218
• 关键词: Address; Behavioral Research; Biochemical; Biological; Biological Assay; Biological Products; Biomedical Research; Cancer Biology; Cancer Burden; Cancer Center; Cancer Center Support Grant; Cancer Control; Characteristics; Chinese People; Clinical Research; Collaborations; Colorectal Cancer; Community Outreach; Diagnosis; Discipline; Education; Educational Activities; Educational Curriculum; Educational workshop; Electronic Mail; Environment; Ethnic Origin; Ethnic group; European; Faculty; Filipino; Filipino American; Funding; Future; Goals; Guam; Hawaii; High School Student; Incidence; Individual; Interdisciplinary Study; Island; Japanese American; Japanese Population; Koreans; Malignant Neoplasms; Malignant neoplasm of liver; Malignant neoplasm of lung; Malignant neoplasm of pharynx; Malignant neoplasm of prostate; Malignant neoplasm of thyroid; Mentors; Mission; NCI Center for Cancer Research; Native Hawaiian; Natural Product Drug; Natural Products; Oral cavity; Organism; Pacific Island Americans; Participant; Patient Care; Persons; Philanthropic Fund; Physical environment; Polynesian; Population; Population Sciences; Prevention; Preventive; Process; Professional Organizations; Research; Research Personnel; Research Training; Resources; Running; Science; Students; Surveys; System; Talents; Training; Training Programs; United States; Universities; anticancer research; base; cancer health disparity; cancer prevention; cancer therapy; career; career development; drug development; drug discovery; education planning; education research; eligible participant; empowerment; experience; faculty research; field study; graduate student; hands on research; health disparity; improved; low socioeconomic status; malignant breast neoplasm; malignant stomach neoplasm; medical schools; member; mortality; multi-ethnic; multidisciplinary; next generation; novel; prevent; programs; ranpirnase; recruit; skills; small molecule; social media; success; summer internship; summer research; tumor initiation; undergraduate student

This proposal will establish a training program called “Cancer Research Education, Advancement, Training and Empowerment” (CREATE) at the University of Hawai`i Cancer Center (UHCC). The program addresses the over-arching goal to enhance the training of a workforce to meet biomedical, behavioral, and clinical research needs to lower cancer incidence and mortality in the Pacific. CREATE takes advantage of the excellent research opportunities arising from the distinctive population and environment in Hawai`i and the Pacific with strong multi-disciplinary collaborations at the University of Hawai`i and its collaborations with the University of Guam. Research training in our multiethnic population with persons of Native Hawaiian, Pacific Islander, Japanese, Filipino, Chinese, Korean, and European ancestry is important to address cancer health disparities due to ethnicity and low socio-economic status while the unique biologic resources and natural compounds found nowhere else in the world will prepare the next generation of researchers for drug discovery and mechanistic cancer research to create new cancer treatments. Besides the 10-week hands-on experience at UHCC, CREATE will include a curriculum of multi-disciplinary seminars, workshops, and career development sessions. Success of the program will be evaluated through several indicators, e.g., proportion of participants in biomedical graduate programs and research careers, based on long-term tracking by surveys, email, social media, and personal contacts. The goal of CREATE to offer distinctive training experiences in cancer biology and in population sciences will be achieved through the implementation of the following aims: 1. Provide hands-on summer research experiences and a multi-disciplinary curriculum to undergraduate students residing in the Islands of Hawai`i and the Pacific to reinforce their intent to graduate with a science degree and to consider a career to address health disparities and contribute to drug discovery. 2. Offer first-year graduate students living in Hawai`i and the Pacific in cancer-related fields of study the opportunity to gain a 1-semester research experience in a multiethnic environment or unique cancer biology labs with the goal to enhance their skills to address causes, diagnosis, prevention, and treatment of cancer and to improve competitiveness in their future careers in cancer-related research. The program builds upon the many years of success of UHCC's Summer Internship Program that has provided research experiences to more than 220 students over the last 10 years and was previously funded by a CURE supplement to the P30 Cancer Center Support Grant and by philanthropic funds. The large pool of potential participants will represent the distinct ethnic composition of students from Hawai`i and Guam. In summary, CREATE will offer students in Hawai`i and the Pacific a unique research experience in population sciences or cancer biology that will enable them to pursue successful careers in cancer prevention and control.

该提案将建立一个名为“癌症研究教育、进步、培训”的培训计划 夏威夷大学癌症中心 (UHCC) 的“和赋权”(CREATE)。 总体目标是加强劳动力培训，以满足生物医学、行为和临床的要求 研究需要利用 CREATE 来降低太平洋地区的癌症发病率和死亡率。 夏威夷独特的人口和环境以及 太平洋大学与夏威夷大学及其与 关岛大学对我们的多民族人口进行研究培训，其中包括太平洋夏威夷原住民。 岛民、日本人、菲律宾人、中国人、韩国人和欧洲人的血统对于解决癌症健康问题很重要 由于种族和社会经济地位低下而造成的差异，而独特的生物资源和自然条件 世界上其他地方找不到的化合物将为下一代药物研究人员做好准备 除了为期 10 周的实践之外，还开展癌症发现和机制研究，以创造新的癌症治疗方法。 CREATE 的 UHCC 经验将包括多学科研讨会、讲习班和职业生涯课程 该计划的成功将通过几个指标来评估，例如比例。 生物医学研究生课程和研究职业的参与者的数量，基于长期跟踪 CREATE 的目标是提供独特的培训。 癌症生物学和人口科学方面的经验将通过实施 以下目标： 1. 提供实践暑期研究经验和多学科课程 居住在夏威夷群岛和太平洋地区的本科生，以强化他们的意图 获得科学学位并考虑从事解决健康差距和问题的职业 为药物发现做出贡献。 2. 为居住在夏威夷和太平洋地区的一年级研究生提供与癌症相关的研究领域 有机会在多民族环境或独特的环境中获得一学期的研究经验 癌症生物学实验室的目标是提高他们解决原因、诊断、 预防和治疗癌症，并提高他们未来职业生涯的竞争力 癌症相关研究。 该计划建立在 UHCC 暑期实习计划多年成功的基础上，该计划已 在过去 10 年里为 220 多名学生提供了研究经验，并曾获得过资助 由 P30 癌症中心支持补助金的 CURE 补充和大型慈善基金提供。 的潜在参与者将代表来自夏威夷和关岛的学生的独特种族构成。 总之，CREATE 将为夏威夷和太平洋地区的学生提供独特的人口研究体验 科学或癌症生物学将使他们能够在癌症预防和治疗方面追求成功的职业生涯 控制。