A Three-dimensional Morphological Study on the Development of Nerves, Vessels and Muscles in the Branchial Organs

鳃器官神经、血管和肌肉发育的三维形态学研究

• 批准号: 10670010
• 负责人: TANAKA Shigenori
• 金额: $ 1.98万
• 依托单位: Kanazawa University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 1998
• 资助国家: 日本
• 起止时间: 1998 至 1999
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-10670010/
• 关键词: development; peripheral nerves; heart; human; Suncus murinus; chicken; rat; immunohistochemistry

1) Development of Vagal Branches destined to the heart and great vessels of chick and Suncus embryosIn 1998, we traced developing branches arising from the trunk of the vagus nerve in the chick embryos and the embryos of the house shrews (Suncus murinus). The results obtained by the observation in the whole-mount stained embryos by a immunohistochemical method using antibodies to the nerves and nerve cells are new and of importance for considering the three-dimensional morphology of these nerve elements to the developing heart as well as to the great vessels. Unfortunately, we encountered a great difficulties in describing the e nerve branches, that is the confusion of terms of the cardiac nerve branches. For the aim to clear and overcome thisdifficulties, we dissected the thoracic viscera and vagal nerve branches to the heart and great vessels under a stereomicroscope and traced the full-course from their origin to the final distribution in the heart. The observed nerves branches were … More named from the developmental viewpoint. In this way, we have found an excellent way of terminology in which every cardiac nerve branches of any vertebrates can be named without causing confusion. This result has been published in Acta Anatomica Nipponica 73 in 1998.The results obtained in the study of chick embryos has been published, though in part, in "Seitai no Kagaku" (Science of Living Bodies).2) Vagal and Sympathetic Nerve Branches Distributed to the Heart and Great Vessels of HumansIn the same way applied to the study 1 mentioned just above, we traced vagal and sympathetic cardica nerves branches in greater detail than ever. We fond, in addition to the vagal cardiac branches, which pass through the aortic porta of the heart, nerves branches entering the venous porta to be distributed to the atria and the interatrial septum. We have made a manuscript of these findings and sent to referee of Journal of Anatomy (England) ; this manuscript has been tentatively accepted, being required to add the findings on the sympathetic cardiac nerve branches.3) Sympathetic Cardiac Nerve Branches to the Heart of the House Shrews, Suncus murinusObservation of the total course of sympathetic cardiac nerves branches is very difficult, or impossible in practice, because the scanty of myelination of these nerve branches. For overcome this difficulty, we have tries a whole-mount staining of the thoracic organs including the heart and great vessels by use of antibodies to neurofilament ; By this method, the total course of the vagal and sympathetic cardiac nerve branches are clearly observable. We have got a new data that the sympathetic cardiac nerve branches destined for the venous portion of the heart take their course along the great venous vessels, I.e., the superior caval veins and the pulmonary veins. We made presentation in the local and general Scientific Meeting of the Japanese Anatomical Association in 1999 and 2000.4) Another FindingsWe have traced the variant artery coursing in the interatrial septum of the human heart. The manuscript of this findings has been sent to the referees of Acta Anatomica Nipponica, ; this has been tentatively accepted, some reverses being required. Less

1）发育于心脏和巨大的小鸡和胚胎胚胎的巨大血管，1998年，他在雏鸡胚胎中的阴道神经和房屋的胚胎（suncus murinus）中的胚胎。 - 使用对神经和神经细胞抗体的免疫组织化学方法的胚胎胚胎对于考虑到发育中心的三维形态是对伟大血管的某些疾病的三维形态，这是对伟大的血管的一些重要性，我们在描述中遇到了很大的差异，这是新的重要性。 Enerve分支机构的目的是清除和克服这一问题，我们将胸神经和迷走神经分支剖析到心脏，grea greart，Greart和Greart and greart and Greart and Greart and Greart and Greart and and Great and and the Full Course从心脏中的最终分布从发展的角度来看，我们找到了一种出色的术语方式，在1998年，在Acta Anatomica 73中，每个人的心脏神经分支机构都没有。在某种程度上，在某些“ seitai no kagaku”中（生命的科学）。2）在上方，我们比以往任何时候都更详细地追溯了迷走神经和富有同情心的Cardica神经。心脏和原子间隔的心脏。众议院的心脏，Suncus murinusobserative of总体心神经分支的总过程的总过程非常困难，或者在实践中是不可能的，这是这些神经分支的缺乏通过使用神经丝的抗体，包括心脏和一些伟大的血管，这是可以观察到的神经分支的整个过程。骑兵静脉和肺部静脉。 Anatomica Nipponica；这是暂定的，需要一些逆转

项目成果

Nakatani T, Izumi A, Tanaka S: "Bilateral superficial median arteries."Journal of Anatomy. 194. 475-477 (1999)

Nakatani T、Izumi A、Tanaka S：“双侧浅正中动脉。”解剖学杂志。

Tanaka S: "The Peripheral Nervous System. In Sato T and K Akita (eds) The Body of Japanese with Discussion of the Anatomical Variations (in Japanese)"Tokyo University Press, Tokyo. 474-477, 511-517, 615-616, 634-639 (1999)

田中 S：“周围神经系统。佐藤 T 和 K 秋田（编）《日本人的身体与解剖变异的讨论》（日文）”东京大学出版社，东京。

Tanaka S, Nakatani T, Mizukami S. Yasui K, Uemura M, Lee H-Y, I-H Chung: "Branches of the vagus nerve destined for the heart and the adjoining great vessels in the house shrew, Suncus murinus, with reference to the terminology of the vagal cardiac branche

Tanaka S、Nakatani T、Mizukami S. Yasui K、Uemura M、Lee H-Y、I-H Chung：“家鼩​​（Suncus murinus）中迷走神经的分支和毗邻的大血管，参考术语

田中重徳: "日本人のからだ 解剖的変異の考察 佐藤達夫、秋田恵一編 末梢神経系"東京大学出版会.

Shigenori Tanaka：“日本身体：解剖变异的考虑：周围神经系统，由佐藤龙夫和秋田敬一编辑”，东京大学出版社。

Nakatani T: "Bilateral four-headed biceps brachii muscles:the median nerve and brachial artery passing through a tunnel formed by a muscle slip from the accessory head" Clinical Anatomy. 11. 209-212 (1998)

Nakatani T：“双侧四头肱二头肌：正中神经和肱动脉穿过由副头肌肉滑落形成的隧道”临床解剖学。