A THREE-DIMENSIONAL STUDY ON THE DEVELOPMENT OF THE NERVES,VESSELS AND THE MUSCLES IN THE CHICK AND MAMMALIAN EMBRYOS USING A WHOLE MOUNT-IMMUNOHISTOCHEMICAL STAINING

免疫组织化学染色法对鸡和哺乳动物胚胎神经、血管和肌肉发育的三维研究

基本信息

批准号：
07670006
负责人：
TANAKA Shigenori
金额：
$ 1.47万
依托单位：
KANAZAWA UNIVERSITY
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
1995
资助国家：
日本
起止时间：
1995 至 1996
项目状态：
已结题

项目摘要

1) Development of the vagal cardiac branches (VCB) in chick embryos By tracing the growth of the VCB at earlier stages of chick embryos, we found that the VCB are divided into 2 groups, those destined for the arterial site and those for venous site of the heart. Most important findings in this study that these VCB reveals a simple symmetrical, but not a complex, arrangement in contrast to the description in the leading anatomical as well as the embryological textbooks. Especially, the VCB destined for the venous site were found to follow the developing the superior vena cava and the pulmonary veins, reaching the sinuatrial node and the interatrial septum, the site of location of the atrioventricular node.2) Unfortunately, the terminology of the VCB of humans and of vertebrates are greatly confused. Every author has applied the same terms to different branches arising from the vagal nerve. For clearing this confusion, we have performed macroscopical studies on the VCB in the chicken, rats, house shrews, and in human adults, and elucidated the morphological features of these branches in a more exact and detailed than ever manner. The results obtained in this study provide us with suff icient evidence to support a confident statement that the fundamental features of the VCB in humans are the same as those in vertebrates, including chicken.

1）通过追踪小鸡胚胎的早期VCB的生长，在雏鸡胚胎中开发迷路心脏分支（VCB），我们发现VCB分为两组，那些注定为动脉部位的部位，而静脉部位的部位则分为心脏。在这项研究中，最重要的发现是这些VCB揭示了与领先的解剖学和胚胎学教科书中的描述相比，简单的对称但不复杂的布置。尤其是，发现注定要供静脉部位的VCB遵循开发的上腔静脉和肺静脉，到达辛维族淋巴结和室内隔膜，这是房屋淋巴结的位置位置。2）不幸的是，不幸的是，不幸的是，不幸的是，人类和脊椎动物的VCB非常困惑。每个作者都将相同的术语应用于迷走神经引起的不同分支。为了清除这种混乱，我们已经对鸡，大鼠，房屋sh和人类成年人的VCB进行了宏观研究，并以比以往任何时候都更加精确和详细的方式阐明了这些分支的形态特征。在这项研究中获得的结果为我们提供了足够的证据，以支持一个自信的陈述，即VCB在人类中的基本特征与包括鸡肉在内的脊椎动物相同。