Study of automated perimetry

自动视野检查的研究

基本信息

批准号：
02670784
负责人：
MIYAKE Yozo
金额：
$ 1.34万
依托单位：
Nagoya University
依托单位国家：
日本
项目类别：
Grant-in-Aid for General Scientific Research (C)
财政年份：
1990
资助国家：
日本
起止时间：
1990 至 1991
项目状态：
已结题

项目摘要

We modified an automated projection static perimeter which can measure thresholds with lights of three different wavelengths in light-adapted as well as in dark adapted state. This instrument can evaluate relative states of rod and cone mechanisms respectively within the visual field range of 72 degrees. These modifications also enable dark-adapted two-color static perimetry quantitatively across the visual field including profile measurement.We studied the recovery of static sensitivity using modified Humphrey Field Analyzer (HFA) to measure cone and rod threshold in once detached retina. Also foveal cone densitometry was done in two groups with or without preoperative macular involvement accompanied with a good postoperative recovery of macular sensitivity. Preoperative deterioration detected with HFA was more prominent in rod sensitivity loss. Cone and rod sensitivity recovered rapidly in postoperative one month, followed by gradual recovery up to six months. Rod rocovery was slower than cone until postoperative three months. Among patients with macular involvement and a good recovery of macular sensitivity after surgery, the recovery of visual acuity was variable. Foveal cone densitometry revealed that poor recovery of Visual acuity was accompanied by poor regeneration of cone pigments. These results suggest that functional abnormalities of cone outer segments are present in macular detachment which persist in reattached macula even when the psychophysical sensitivity recovers to normal level.

我们修改了自动投影静态周长，它可以在光适应和暗适应状态下用三种不同波长的光测量阈值。该仪器可在72度视野范围内分别评价杆状机构和锥状机构的相对状态。这些修改还能够在整个视野范围内定量进行暗适应双色静态视野测量，包括轮廓测量。我们使用改进的汉弗莱视野分析仪（HFA）来研究静态灵敏度的恢复，以测量一旦脱离的视网膜中的视锥细胞和视杆细胞阈值。术前有或没有黄斑受累的两组也进行了黄斑中心凹锥光密度测量，术后黄斑敏感性恢复良好。术前用 HFA 检测到的恶化在杆敏感性丧失中更为突出。视锥细胞和视杆细胞的敏感性在术后一个月内迅速恢复，随后逐渐恢复至六个月。直至术后三个月，杆状体的恢复速度比锥状体慢。在黄斑受累且术后黄斑敏感性恢复良好的患者中，视力恢复情况各不相同。中心凹视锥细胞光密度测定显示，视力恢复不良伴随着视锥细胞色素再生不良。这些结果表明，黄斑脱离中存在锥体外节的功能异常，即使心理物理敏感性恢复到正常水平，这种异常也会在重新附着的黄斑中持续存在。