Basic and clinical study of multifocal ERG

多焦ERG的基础与临床研究

• 批准号: 08457462
• 负责人: MIYAKE Yozo
• 金额: $ 4.67万
• 依托单位: Nagoya University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 1996
• 资助国家: 日本
• 起止时间: 1996 至 1997
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-08457462/
• 关键词: multifocal ERG; macular ERG; television monitor; first order; second order; occult macular dystrophy; cone dystrophy; retinitis pigmentosa; 糖尿病黄斑症; 網膜内層障害; m-sequence; クラッシュERG; ON,OFF反応; グルタメートアナログ; occult macular dystropliy; multifocal ERG; macular ERG; television monitor; first order; second order; occult macular dystrophy; cone dystrophy; retinitis pigmentosa; 糖尿病黄斑症; 網膜内層障害; m-sequence; クラッシュERG; ON,OFF反応; グルタメートアナログ; occult macular dystropliy

We studied the multifocal electroretinogram (ERG) in terms of the recording methods, the origin of the response, and the usefulness and limitation in evaluating clinical diseases. We found that some patients with poor visual acuity and central scotoma may show poor fixation during recording, which may cause a significant artifact. In such case, we proved that the fundus monitor is essential through the infrared television fundus camera during recording.In comparison with the conventional focal macular ERG,the a-wave in multifocal ERG was proved to have the same origin to that of conventional multifocal ERG.We found a macular dystrophy with a new clinical entity where the ophthalmoscopical macular finding is normal and only the multifocal ERg shows enormous abnormality. We termed "Occult Macular Dystrophy" for this disorder.

我们根据记录方法，反应的起源以及评估临床疾病的有用性和局限性研究了多灶性电视图（ERG）。我们发现，一些视力差和中央Scotoma的患者在记录过程中可能显示出较差的固定性，这可能会导致显着的伪影。在这种情况下，我们证明了眼底监测器在录制过程中通过红外电视镜头摄像机至关重要。与常规的焦点黄斑ERG相比，多焦点ERG中的A波与常规多焦点ERG具有相同的起源。我们与常规的多焦点eRG相同。我们发现了一个新的临床上的Macular and Issmority and Machimorals Machormors andif propralitials Maclasicals Maclymos Maclymosissions 紊乱 etc。我们称这种疾病为“隐匿性黄斑营养不良”。