Degeneration of Machine oils and the generation of toxicity during Their Recycled use- Studies from the view point of industrial health.

机械油的变质及其回收使用过程中毒性的产生 - 从工业健康角度进行的研究。

基本信息

批准号：
61570274
负责人：
KIRA Shohei
金额：
$ 1.28万
依托单位：
Okayama University Medical School
依托单位国家：
日本
项目类别：
Grant-in-Aid for General Scientific Research (C)
财政年份：
1986
资助国家：
日本
起止时间：
1986 至 1988
项目状态：
已结题

项目摘要

Machine oils are widely used in metal processing factories and a water soluble or emulsifiable type has become predominant in the work place. During their recycled use process, a high temperature and a high pressure on the metal surface could play a role in generating new toxic substances unpredicted before use. The present studies concern the detection of mutagenicity and its monitoring in cutting fluids with the lapse of time of recycled use, and the measurement of oil mists in the work places.1. After the blue cotton extraction, one of 11 unused water soluble cutting fluids tested here showed mutagenic activity detected by the Ames test with Salmonella TA98 without metabolic activation. 2. With the Sep-Pak C18 extraction, polar fractions of an unused and a recycle-used water soluble cutting fluids showed mutagenicity by TA100 without metabolic activation. 3. Some machine oils being collected as the lapse of time showed mutagenicity after 60-90 days of use. 4. As a portable sampler for oil mists, we tested a head of the TR sampler with two stages built in, and collected the oil mists on stainles-steel plate. We also tested an oil meter for the measurement of oil components collected on the plate after extraction with CC14. The results were well corresponded to those with the low volume sampler, which collects the oil mists in a glass fiber filter and is a conventional method.The above results suggested that monitorings of both the levels of oils in the ambient air and the toxicities such as mutagenicity in the fluid, could work for the protection of health of worker in machine work shops, through an environmental control system.

机器油被广泛用于金属加工厂，水溶性或可乳化的类型已在工作场所占主导地位。在其再生用途过程中，金属表面的高温和高压可能在使用前未预测的新有毒物质中发挥作用。本研究涉及诱变性及其在切割液体中的监测，随着回收使用时间的流逝，以及在工作场所中的石油雾的测量。1。蓝色棉花提取后，这里测试的11种未使用的水溶性切割液中的一种显示，通过使用沙门氏菌TA98的AMES测试检测到诱变活性，而无需代谢激活。 2。随着SEP-PAK C18提取，未使用的未使用的极性部分和回收的水溶性切割液显示出TA100的诱变，而无需代谢激活。 3。在使用60-90天后，某些机器油被收集在时间的流逝中。 4。作为石油雾的便携式采样器，我们测试了一个内置两个阶段的TR采样器的头部，并在Stainles-Steel Plate上收集了油雾。我们还测试了用CC14提取后在板上收集的机油组件的测量机计量表。结果很好地对应于具有低体积采样器的那些，后者在玻璃纤维过滤器中收集油漆，并且是常规方法。上述结果表明，对环境空气中的油水平的监测以及流体中的毒性等毒性，可以通过环境控制系统来保护工人工作室中的工作人员的健康状况。