Next generation of IVMFC technical development by identification of the microtubule control factor of oocyte.
通过鉴定卵母细胞微管控制因子开发下一代 IVMFC 技术。
基本信息
- 批准号:21248032
- 负责人:
- 金额:$ 30.2万
- 依托单位:
- 依托单位国家:日本
- 项目类别:Grant-in-Aid for Scientific Research (A)
- 财政年份:2009
- 资助国家:日本
- 起止时间:2009 至 2011
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Improve spectacularly of in vitro maturation (IVM) of an immature oocyte which makes the core of in vitro culture system of oocyte is aimed, it focused on localization, morphology and function of the microtubules (e.g. gap junction, nuclear membrane, chromosome, endoplasmic reticulum, spindle, mitochondria, cortical granule) of an immature oocyte, and identified the control agent. Furthermore, the chemical substance which controls expression of a control agent artificially was searched.
显着提高未成熟卵母细胞的体外成熟(IVM),使卵母细胞体外培养系统的核心针对微管(如间隙连接、核膜、染色体、内质网等)的定位、形态和功能、纺锤体、线粒体、皮质颗粒)的未成熟卵母细胞,并鉴定了对照剂。进而,还探索了人工控制控制剂的表达的化学物质。
项目成果
期刊论文数量(24)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Akt expression in mouse oocytes matured in vivo and in vitro
- DOI:10.1016/j.rbmo.2009.10.011
- 发表时间:2010-01-01
- 期刊:
- 影响因子:4
- 作者:Cecconi, Sandra;Rossi, Gianna;Macchiarelli, Guido
- 通讯作者:Macchiarelli, Guido
Molecular basis of follic ular growth and oocyte maturation-Use of farm animals for biology andbiomedical sience
卵泡生长和卵母细胞成熟的分子基础-农场动物在生物学和生物医学科学中的应用
- DOI:
- 发表时间:2010
- 期刊:
- 影响因子:0
- 作者:Sato;E
- 通讯作者:E
排卵と受精、生殖卵巣学(石塚文平、鈴木秋悦編)
排卵与受精、生殖卵巢学(石冢文平、铃木昭吉编)
- DOI:
- 发表时间:2011
- 期刊:
- 影响因子:0
- 作者:Hirano Y;Kaneko G;Koyama H;Ushio H;Watabe S;佐藤英明
- 通讯作者:佐藤英明
Anomalous oxygen consumption in porcine somatic cell nuclear transfer embryos.
猪体细胞核移植胚胎的异常耗氧量。
- DOI:
- 发表时间:2010
- 期刊:
- 影响因子:0
- 作者:Fujita K.;Sato K;藤田貴志,野口航,寺島一郎;佐藤英明
- 通讯作者:佐藤英明
Leukocyte count in follicular aspirate samples could be a prognostic biomerker of the developmental competence of human metaphase II oocytes
卵泡抽吸样本中的白细胞计数可能是人类中期 II 卵母细胞发育能力的预后生物标志物
- DOI:
- 发表时间:2012
- 期刊:
- 影响因子:0
- 作者:Ishikawa;T.;Doshida;M.;Kyoya;T.;Takizawa;T.;Sakura;M.;Hoshino;Y.;Tanemura;K.;Kyono;K.;Sato;E
- 通讯作者:E
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{{ truncateString('SATO Eimei', 18)}}的其他基金
Improvement of IVM based on the elucidation of meiosis pause mechanism by uppermost stream factor identification of oocyte maturation inhibitory factor group
基于卵母细胞成熟抑制因子群最上游因子鉴定阐明减数分裂暂停机制的IVM改进
- 批准号:
23658236 - 财政年份:2011
- 资助金额:
$ 30.2万 - 项目类别:
Grant-in-Aid for Challenging Exploratory Research
Development of fundamental basis for embryo-biotechnology in next generation by clarifying the regulatory mechanisms of cell differentiation and apoptosis of oocytes
阐明卵母细胞分化和凋亡的调控机制,为下一代胚胎生物技术奠定基础
- 批准号:
16108003 - 财政年份:2004
- 资助金额:
$ 30.2万 - 项目类别:
Grant-in-Aid for Scientific Research (S)
Identification of genes and angogenic factors involving in selective growth and apoptosis of oocytes
鉴定参与卵母细胞选择性生长和凋亡的基因和血管生成因子
- 批准号:
13460129 - 财政年份:2001
- 资助金额:
$ 30.2万 - 项目类别:
Grant-in-Aid for Scientific Research (B)
Identification of biological factors involving in serial culturing technique for germ cell series
生殖细胞系列连续培养技术涉及的生物因子的鉴定
- 批准号:
10306018 - 财政年份:1998
- 资助金额:
$ 30.2万 - 项目类别:
Grant-in-Aid for Scientific Research (A).
The production of transgenic pigs for xenotransplantation
用于异种移植的转基因猪的生产
- 批准号:
10556059 - 财政年份:1998
- 资助金额:
$ 30.2万 - 项目类别:
Grant-in-Aid for Scientific Research (B).
active substance regulating differentiation of germ lines
调节种系分化的活性物质
- 批准号:
08456147 - 财政年份:1996
- 资助金额:
$ 30.2万 - 项目类别:
Grant-in-Aid for Scientific Research (B)
Porcine embryonic stem cells forming germ line chimeras
猪胚胎干细胞形成种系嵌合体
- 批准号:
07506005 - 财政年份:1995
- 资助金额:
$ 30.2万 - 项目类别:
Grant-in-Aid for Scientific Research (A)
Regulatory mechanisms of selective growth and death of oocytes
卵母细胞选择性生长和死亡的调控机制
- 批准号:
06454123 - 财政年份:1994
- 资助金额:
$ 30.2万 - 项目类别:
Grant-in-Aid for General Scientific Research (B)
Physiologically active substances regulating ovarian function
调节卵巢功能的生理活性物质
- 批准号:
03454098 - 财政年份:1991
- 资助金额:
$ 30.2万 - 项目类别:
Grant-in-Aid for General Scientific Research (B)
Improvement of meiotic competence of follicular oocytes by artificial techniques
通过人工技术提高卵泡卵母细胞减数分裂能力
- 批准号:
61560305 - 财政年份:1986
- 资助金额:
$ 30.2万 - 项目类别:
Grant-in-Aid for General Scientific Research (C)
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- 批准号:
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- 资助金额:
$ 30.2万 - 项目类别:
Industrial R&D Fellowships (IRDF)
Construction of the basis oflymph node tissue microenvironment by stromal cell derived factors
基质细胞衍生因子构建淋巴结组织微环境基础
- 批准号:
22790194 - 财政年份:2010
- 资助金额:
$ 30.2万 - 项目类别:
Grant-in-Aid for Young Scientists (B)
Immunological and physiological analysis of the function and construction of stromal cell network in secondary lymphoid organ
次级淋巴器官基质细胞网络的功能和构建的免疫学和生理学分析
- 批准号:
20689005 - 财政年份:2008
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