MRI: Acquisition of a High-Resolution Mass Spectrometer for Research in Chemical Synthesis, Materials, and Biological Sciences

MRI：购买高分辨率质谱仪用于化学合成、材料和生物科学研究

• 批准号: 2215975
• 负责人: Frieder Jaekle
• 金额: $ 39万
• 依托单位: Rutgers University Newark
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-08-15 至 2025-07-31
• 项目状态: 未结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2215975&HistoricalAwards=false
• 关键词: MRI; Acquisition; Resolution; Mass; Spectrometer

This award is jointly supported by the Major Research Instrumentation and the Chemistry Research Instrumentation Programs. Rutgers University – Newark is acquiring a high-resolution mass spectrometer (HRMS) equipped with electrospray Ionization (ESI), atmospheric pressure chemical ionization (APCI), and Direct Analysis in Real Time (DART) to support the research of Professor Frieder Jaekle and colleagues Elena Galoppini, Haesun Kim, Michal Szostak, and Colin Kinz-Thompson. This instrument facilitates research in the areas of organic chemistry, catalysis, semiconductors, inorganic chemistry, biochemistry, and biological sciences. In general, mass spectrometry (MS) is one of the key analytical methods used to identify and characterize small quantities of chemical species embedded in complex samples. In a typical experiment, the components are heated and flow into a mass spectrometer where they are ionized. The ions' masses are measured very accurately. The capabilities of the mass spectrometer instrument are augmented by complementary ESI and ambient pressure APCI and DART sources and will serve a wide host of research needs. The acquisition strengthens the research infrastructure at the University and regional area. This instrument enhances the educational, research, and teaching efforts of students at all levels in many departments as well as provides accessibility for use at nearby institutions. The instrument gives students experience using vital instrumentation that they carry with them into their careers. The research groups using the instrument are also actively participate in multiple successful programs to aid recruiting from underrepresented groups. The award of this mass spectrometer is aimed at enhancing research and education at all levels. The new instrument will serve as an important characterization tool for research that spans areas ranging from synthetic chemistry, catalysis, materials science to biophysical and biological sciences. research will be enabled in amide bond activation, cross-coupling and catalysis, organocatalysis and green synthesis, molecular electrocatalysts for energy conversion, chromophore-semiconductor interfaces, organoboranes in materials science and catalysis, bacterial chemosensing, choline transport in myelin-forming glial cells, lipid metabolism in brain health and disease, lysozyme-mediated bacterial cell-wall-processing, and biological sciences.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

该奖项由主要的研究工具和化学研究工具计划共同支持。弗里德·贾克勒（Frieder Jaekle）和同事Elena Galoppini，Michal Szostak Olin Kinz-Thompson教授。在典型的体验中，使用并表征了嵌入复杂样品中的购物中心数量的关键分析方法。 DARCES和将在大学和区域的广泛研究中，这会增强教育程度。一些人将其带入其中的研究小组。从合成化学，催化，材料科学到生物物理学和生物学的范围髓磷脂形成凝胶的运输，脑健康和疾病中的PID代谢，溶菌酶介导的双脚病细胞壁处理以及生物学科学。这项奖项反映了NSF的法定任务，并通过评估基金会的智力通过评估来剥夺了NSF的法定任务优点和更广泛的影响审查标准。