ICBR: Capacity: Biological Collections: Provasoli-Guillard National Center for Marine Algae and Microbiota (NCMA)

ICBR：容量：生物收藏：普罗瓦索利-吉拉德国家海洋藻类和微生物中心 (NCMA)

• 批准号: 2212613
• 负责人: Michael Lomas
• 金额: $ 52.2万
• 依托单位: Bigelow Laboratory for Ocean Sciences
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-08-01 至 2025-07-31
• 项目状态: 未结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2212613&HistoricalAwards=false
• 关键词: ICBR; Capacity; Biological; Collections; Provasoli

Algae have been a natural source of food, feeds and fertilizers for coastal communities for millennia. Modern biotechnology uses of algae in human systems have been rapidly expanding in scope and diversifying in application over the past few decades, in no small part due to the maintenance and availability of algae culture centers. The National Center for Marine Algae and Microbiota (NCMA) at Bigelow Laboratory for Ocean Sciences is a public resource whose mission is to promote, support, and enable the use of algae for foundational research, education, and commercial applications. For nearly four decades, the NCMA has provided this unique resource for researchers, students at all levels, educators and companies worldwide, all interested in working with microalgae to investigate fundamental questions in biology, global processes and biotechnology. This new research funding will continue to support the NCMA in its mission, and importantly expand the value of its algae holdings by supporting the compilation of new and existing data and information about each of the algae strains it holds. Professionally curated microalgae culture collections, from well-respected sources such as NCMA, are essential to support biological research in the United States.The NCMA is one of a small number of culture collections focused on algal biodiversity, and the only one in the U.S. with a primary focus on marine microalgae. The NCMA curates ~2,800 distinct microalgal and ~1600 macroalgal strains isolated from around the world, with many of the algae in the NCMA Collection being unique and representing an irreplaceable genetic resource. The specific scientific objectives of this project are to 1) maximize curated biodiversity of marine microalgae, and expand macroalgae strain holdings; 2) expand high-throughput cryopreservation capabilities in order meet the increasing needs of a diversified user base; 3) generate phenotypic trait data for NCMA strains, namely photoheterotrophic growth capabilities and quantified toxin content; and 4) continue to expand our education/workforce portfolio. Studying curated algae from the NCMA collection provides a genomic, physiological and/or evolutionary compass; it essentially points external researchers in a direction that allows them to develop the appropriate hypotheses, models or diagnostic tools to investigate their questions in nature. Beyond curating algae, the NCMA curators and researchers generate essential research data on the characterization of its collection (e.g., growth rates and capabilities, biochemical characterization, etc.) creating great value to the broader scientific and entrepreneurial communities, and enabling rapid progress in this field.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

藻类一直是数千年来沿海社区的食物，饲料和肥料的自然来源。在过去的几十年中，藻类在人类系统中的现代生物技术用途在范围和应用中的多样化一直在迅速扩展，这在很大程度上是由于藻类培养中心的维护和可用性。 Bigelow海洋科学实验室的国家海洋藻类和微生物群（NCMA）是公共资源，其使命是促进，支持和使藻类用于基础研究，教育和商业应用。在近四十年的时间里，NCMA为全球各个级别的研究人员，教育者和公司提供了这种独特的资源，所有这些都有兴趣与Microalgae一起研究生物学，全球过程和生物技术方面的基本问题。这项新的研究资金将继续支持NCMA的使命，并通过支持有关其所拥有的每种藻类菌株的新数据和信息的汇编，从而扩大其藻类持有量的价值。来自NCMA等备受尊敬的来源的专业策划的微藻文化收藏对于支持美国的生物学研究至关重要。NCMA是针对藻类生物多样性的少数文化收藏之一，在美国唯一一个主要针对海洋微型的培养物。 NCMA策划了约2,800个不同的微藻和〜1600个与世界各地分离的大藻菌株，NCMA收集中的许多藻类都是独特的，代表了不可替代的遗传资源。该项目的特定科学目标是1）最大化海洋微藻的生物多样性，并扩大大藻菌株持有； 2）扩展高通量冷冻保存功能，以满足多元化用户群的不断增长的需求； 3）生成NCMA菌株的表型性状数据，即光旋转的生长能力和量化的毒素含量； 4）继续扩大我们的教育/劳动力投资组合。从NCMA收集中研究策划的藻类提供了基因组，生理和/或进化指南针；从本质上讲，它指向外部研究人员的方向，使他们能够开发适当的假设，模型或诊断工具来研究其自然界的问题。除了策划藻类外，NCMA策展人和研究人员还产生有关其收集表征的重要研究数据（例如，增长率和能力，能力，生物化学特征等），为更广泛的科学和企业家社区创造了巨大的价值，并在此领域迅速取得了迅速的进步。审查标准。