CPS: Medium: Deep Integration of Thin Flexible Autonomous Microsystems for Vision Correction

CPS：中：用于视力矫正的薄型柔性自主微系统的深度集成

基本信息

批准号：
1932602
负责人：
Carlos Mastrangelo
金额：
$ 120万
依托单位：
University of Utah
依托单位国家：
美国
项目类别：
Standard Grant
财政年份：
2019
资助国家：
美国
起止时间：
2019-12-01 至 2023-11-30
项目状态：
已结题

来源：
https://www.nsf.gov/awardsearch/showAward?AWD_ID=1932602&HistoricalAwards=false
关键词：
CPS Medium Deep Integration Thin

项目摘要

The goal of this work is the realization of autonomous cyber-physical, microsystems for automated correction of blurred vision using flexible electronic contact lenses. The vision correction system integrates thin variable power lenses with object distance microsensors and computation and control software to continuously produce sharply-focused images in individuals suffering from presbyopia. Presbyopia, or loss of the eye's ability to change focus, is an inevitable and universal age-related condition that affects aging adults, causing blurred images and visual impairment. In 2018, two billion people worldwide were estimated to suffer from presbyopia. The proposed vision correction microsystem operates autonomously while collecting energy from its surrounding environment in order to provide continuous vision correction for an entire day. Realization of such microsystems advances our scientific knowledge of autonomous microsystem engineering for medical applications, ultimately improving the daily lives and well-being of billions of aging adults while reducing the cost of treatment.The implementation of autonomous microsystems for vision correction requires deep integration of ultrathin state-of-the-art inhomogeneous microtechnologies including variable power liquid-crystal lenses, paper-thin embedded microprocessors and communications circuits with tens of millions of transistors, paper-thin microsensors to detect light level, user orientation and focal distance, and thin photovoltaic cells with power management circuits, all integrated onto a single flexible package that conforms to the surface of the human eye. The system must be able to scavenge power and manage its operation completely autonomously, in the best possible way, in a resource-limited biological environment. Advancements in systems with these characteristics are widely applicable to many future cyber physical systems (CPS) for medical and health monitoring applications. This extremely ambitious project pushes the frontiers of inhomogeneous microtechnology integration to a level that has been repeatedly dreamed of, but never realized before, to produce a highly integrated CPS that can benefit billions of people.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

这项工作的目标是实现自主网络物理微系统，使用柔性电子隐形眼镜自动校正视力模糊。该视力矫正系统将薄型可变倍率镜片与物距微传感器以及计算和控制软件集成在一起，可为老花眼患者持续产生清晰聚焦的图像。老花眼，或者说眼睛改变焦点能力的丧失，是一种不可避免的、普遍的与年龄相关的疾病，它影响老年人，导致图像模糊和视力障碍。 2018年，全球估计有20亿人患有老花眼。所提出的视力矫正微系统在从周围环境收集能量的同时自主运行，以便提供一整天的连续视力矫正。这种微系统的实现提高了我们对医疗应用自主微系统工程的科学知识，最终改善了数十亿老年人的日常生活和福祉，同时降低了治疗成本。实现视力矫正自主微系统需要深度集成超薄最先进的非均质微技术，包括可变功率液晶透镜、薄如纸的嵌入式微处理器和带有数千万个晶体管的通信电路、薄如纸的微传感器，用于检测光线水平、用户方向和焦距、带有电源管理电路的薄型光伏电池，全部集成到一个符合人眼表面的柔性封装中。该系统必须能够在资源有限的生物环境中以尽可能最好的方式完全自主地获取电力并管理其运行。具有这些特征的系统的进步广泛适用于许多未来的医疗和健康监测应用的网络物理系统（CPS）。这个极其雄心勃勃的项目将非均质微技术集成的前沿推向了人们多次梦想但从未实现的水平，以生产出可以造福数十亿人的高度集成的 CPS。该奖项反映了 NSF 的法定使命，并被认为是值得的通过使用基金会的智力优势和更广泛的影响审查标准进行评估来获得支持。

项目成果

期刊论文数量（28）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Adhesion Strength of PDMS to Polyimide Bonding with Thin-film Silicon Dioxide

PDMS与薄膜二氧化硅聚酰亚胺粘合的粘合强度

DOI：
10.1109/fleps51544.2021.9469779
发表时间：
2021-06
期刊：
IEEE FLEPS
影响因子：
0
作者：
Deshpande, Adwait;Pourshaban, Erfan;Ghosh, Chayanjit;Banerjee, Aishwaryadev;Kim, Hanseup;Mastrangelo, Carlos
通讯作者：
Mastrangelo, Carlos

Low-Profile Stacked Digitally Tunable LC Fresnel Lens for Smart Contact Lens System

用于智能隐形眼镜系统的薄型堆叠式数字可调 LC 菲涅尔透镜

DOI：
10.1109/ipc53466.2022.9975492
发表时间：
2022-11
期刊：
2022 IEEE Photonics Conference (IPC
影响因子：
0
作者：
Ghosh, Chayanjit;Banerjee, Aishwaryadev;Karkhanis, Mohit;Pourshaban, Erfan;Kim, Hanseup;Mastrangelo, Carlos H.;Deshpande, Adwait
通讯作者：
Deshpande, Adwait

A Magnetically-Coupled Micromachined Electrostatic Energy Harvester Driven by Eye Blinking Motion

由眨眼运动驱动的磁耦合微机械静电能量采集器

DOI：
10.1109/transducers50396.2021.9495499
发表时间：
2021-06
期刊：
Transducers
影响因子：
0
作者：
Pourshaban, Erfan;Karkhanis, Mohit U.;Deshpande, Adwait;Banerjee, Aishwaryadev;Ghosh, Chayanjit;Kim, Hanseup;Mastrangelo, Carlos H.
通讯作者：
Mastrangelo, Carlos H.

Microfabricated Low-Profile Tunable LC-Refractive Fresnel (LCRF) Lens for Smart Contacts

用于智能隐形眼镜的微加工薄型可调谐 LC 折射菲涅尔 (LCRF) 透镜

DOI：
10.1364/cleo_at.2022.aw4c.3
发表时间：
2022-01
期刊：
Conference on Lasers and Electro-Optics (CLEO
影响因子：
0
作者：
Banerjee, Aishwaryadev;Ghosh, Chayanjit;Karkhanis, Mohit;Deshpande, Adwait;Pourshaban, Erfan;Kim, Hanseup;Mastrangelo, Carlos H.
通讯作者：
Mastrangelo, Carlos H.

A Nano-Joule Burst-Mode Eye-Gaze Angle and Object Distance Sensor for Smart Contact Lenses

用于智能隐形眼镜的纳焦耳突发模式眼睛注视角度和物体距离传感器

DOI：
10.1109/sensors47087.2021.9639572
发表时间：
2021-10
期刊：
IEEE Sensors
影响因子：
0
作者：
Ghosh, Chayanjit;Kalidasan, Sakthidasan;Karkhanis, Mohit U.;Mastrangelo, Ale;Banerjee, Aishwaryadev;Walker, Ross;Kim, Hanseup;Mastrangelo, Carlos H.
通讯作者：
Mastrangelo, Carlos H.