MRI: Acquisition of an X-ray Diffractometer at Purdue University

MRI：在普渡大学购买 X 射线衍射仪

• 批准号: 1625543
• 负责人: Tong Ren
• 金额: $ 21.85万
• 依托单位: Purdue University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-09-01 至 2019-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1625543&HistoricalAwards=false
• 关键词: MRI; Acquisition; ray; Diffractometer; Purdue

With this award from the Major Research Instrumentation Program (MRI) and support from the Chemistry Research Instrumentation Program (CRIF), Professor Tong Ren from Purdue University and colleagues Matthias Zeller and Suzanne Bart have acquired a single crystal X-ray diffractometer equipped with a molybdenum source. In general, an X-ray diffractometer allows accurate and precise measurements of the full three-dimensional structure of a molecule, including bond distances and angles, and provides accurate information about the spatial arrangement of a molecule relative to neighboring molecules. These studies impact a number of areas, including organic and inorganic chemistry, materials chemistry and biochemistry. This instrument is an integral part of teaching as well as research and research training of undergraduate and graduate students in chemistry and biochemistry at this institution that awards one of the largest number of PhD degrees in the country. The X-ray facility has a tradition of providing data collection and structure solution services for faculty and students from small colleges (PUIs) in the surrounding area. The diffractometer allows this courtesy to remain and be expanded. Finally, building on Purdue's ongoing efforts of making modern research instrumentation available at K-12 levels through the Purdue Science Express Program, the use of X-ray diffraction for K-12 educational purposes is being explored.The award is aimed at enhancing research and education at all levels, especially in areas such as (a) synthesizing conjugated metal acetylides, (b) studying organometallic chemistry of uranium complexes, (c) designing, preparing and investigating single-site catalysts used in green and sustainable chemistry transformations, (d) synthesizing bioactive molecules, (e) designing new HIV-1 protease inhibitors and (f) synthesizing highly reactive radical species.

凭借重大研究仪器计划 (MRI) 的奖项和化学研究仪器计划 (CRIF) 的支持，普渡大学的 Tong Ren 教授及其同事 Matthias Zeller 和 Suzanne Bart 购买了一台配备钼的单晶 X 射线衍射仪来源。一般来说，X 射线衍射仪可以精确测量分子的完整三维结构，包括键距和角度，并提供有关分子相对于相邻分子的空间排列的准确信息。这些研究影响了许多领域，包括有机和无机化学、材料化学和生物化学。该仪器是该机构化学和生物化学本科生和研究生教学以及研究和研究培训的重要组成部分，该机构是全国授予博士学位数量最多的机构之一。 X 射线设施具有为周边地区小型学院 (PUI) 的教职员工和学生提供数据收集和结构解决方案服务的传统。衍射仪使这种礼貌得以保留并得以扩展。最后，在普渡大学通过普渡科学快车计划为 K-12 年级提供现代研究仪器的持续努力的基础上，正在探索将 X 射线衍射用于 K-12 教育目的。该奖项旨在加强研究和各级教育，特别是在以下领域：(a) 合成共轭金属乙炔化物，(b) 研究铀络合物的有机金属化学，(c) 设计、制备和研究用于绿色和可持续化学的单中心催化剂转化，(d) 合成生物活性分子，(e) 设计新的 HIV-1 蛋白酶抑制剂，以及 (f) 合成高反应性自由基物质。