REU Site: Discoveries in Bioimaging

REU 网站：生物成像的发现

• 批准号: 1461038
• 负责人: Stephen Boppart
• 金额: $ 36万
• 依托单位: University of Illinois at Urbana-Champaign
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-03-01 至 2019-02-28
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1461038&HistoricalAwards=false
• 关键词: REU; Site; Discoveries; Bioimaging

BROADER SIGNIFICANCE OF THE PROJECT:The REU site "Discoveries in Bioimaging" at the University of Illinois at Urbana-Champaign (UIUC) will provide a state-of-the-art, interdisciplinary research environment in bioimaging to inspire and train undergraduates from under-represented demographics in engineering to encourage their transition to graduate degree programs. Throughout the educational process, visuals are a powerful means to clearly convey complex ideas and to stimulate curiosity and interest. Likewise, investigations in the biological and medical sciences invariably require clear pictures of cells, tissues, and organs to discover mechanisms of life and to detect and understand the complex pathological processes of disease. The unifying link between bioscience, discovery, and bioimaging will be the inspirational centerpiece for the new REU site. Students who take part in this REU program will gain an intimate familiarity with how biological discoveries directly arise from imaging, and gain an advanced skillset in state-of-the-art imaging technologies and interdisciplinary research that they can carry with them to graduate school. They will be exposed to the vast breadth of bioimaging techniques and applications while simultaneously focusing on a specific project at the forefront of biology and medical science. Furthermore by implementing literature-supported mentorship and training strategies, this program will directly address pipeline leaks for the transition of under-represented groups to engineering graduate degree programs. Those who choose to not pursue graduate studies will still be enriched with technical skills, professionalism, and career-readiness. The attributes of our program, both those that are successful, or perhaps ineffective, will be constantly assessed and refined, and findings will be disseminated to the public through publications in educational journals.PROJECT DESCRIPTION:With the support from the NSF Division of Engineering Education and Centers, the REU Site will be dedicated to inspiring and training undergraduates in STEM fields through a summer experience in bioimaging research. The goal is to create a coherent interdisciplinary program centered on the visualization of biology and medical science at all scales in which students develop a network of role models, mentors, and peers to support and encourage their transition to graduate school. Undergraduates finishing their freshman, sophomore, and junior years in a variety of STEM disciplines will be recruited with special efforts directed toward females and under-represented minorities, especially those at minority-serving institutions and small colleges with limited research opportunities. In addition, highly motivated community college students who are en route to 4-year colleges and universities, will be included. Students will begin this 10-week summer program with a 5-day "Bioimaging Bootcamp" to provide foundational knowledge in biology, imaging, and microscopy through lectures, demonstrations, lab activities, and tours, in conjunction with social introductions. Over the next nine weeks, students will engage in intensive research projects in imaging and biological visualization, closely mentored by a faculty member and graduate student, with assistance from an experienced UIUC undergraduate. All research projects, ranging from imaging single molecules using fluorescence microscopy to tracking cell dynamics in the skin of live animals, will have three essential elements: (1) imaging and/or microscopy, (2) an application directed toward biological or medical sciences, and (3) an analytical or computational component. Students will share experiences with their cohort through biweekly social activities, attend research seminars and professional development sessions, and interact with participants in other REUs on campus to expand their network. Summer achievements will culminate in the submission of an abstract to the Biomedical Engineering Society (BMES) Annual Fall Meeting, where they will reconvene in the fall for continued education and career-enriching opportunities.

该项目的更广泛的意义：在Urbana-Champaign（UIUC）伊利诺伊大学的REU网站“生物成像”（UIUC）将提供一个最先进的，跨学科的研究环境，以激发生物成像，以激发和培训从工程学范围不足的人际教育范围内培训过度范围的人群，以鼓励其过渡到毕业学位课程。在整个教育过程中，视觉效果是清晰传达复杂思想并刺激好奇心和兴趣的强大手段。 同样，对生物学和医学科学的研究总是需要清晰的细胞，组织和器官的图片，以发现生命的机制，并检测和理解疾病的复杂病理过程。生物科学，发现和生物成像之间的统一联系将是新REU网站的鼓舞人心的核心。 参加此REU计划的学生将对生物学发现如何直接从成像引起，并获得最先进的成像技术和跨学科研究的高级技能，并获得他们可以随身携带的研究生院。 他们将暴露于生物成像技术和应用的广度，同时专注于生物学和医学最前沿的特定项目。 此外，通过实施文学支持的指导和培训策略，该计划将直接解决泄漏的管道泄漏，以过渡到代表性不足的小组向工程研究生学位课程。 那些选择不从事研究生学习的人仍然会充满技术技能，专业精神和职业准备。 我们计划的属性，无论是成功或可能无效的计划的属性，都将不断评估和完善，并且发现将通过教育期刊中的出版物向公众分散。目的是创建一个连贯的跨学科计划，该计划以各种规模的生物学和医学科学的可视化为中心，在该计划中，学生开发了榜样，导师和同伴网络，以支持和鼓励他们过渡到研究生院。在各种STEM学科中完成新生，大二和大三的本科生将通过针对女性和代表性不足的少数群体的特殊努力，尤其是那些在少数族裔服务机构和小学院的小学学院的特殊努力，并具有有限的研究机会。此外，将包括进入四年制大学和大学的途中的积极进取的社区大学生。学生将通过为期5天的“生物成像训练营”开始这个为期10周的夏季计划，以通过讲座，演示，实验室活动和旅行与社会介绍一起提供生物学，成像和显微镜的基础知识。在接下来的九周内，学生将在经验丰富的UIUC本科生的协助下，由教职员工和研究生密切指导成像和生物可视化的密集研究项目。从使用荧光显微镜进行成像的单分子到跟踪活动物皮肤中的细胞动力学的所有研究项目都将具有三个基本要素：（1）成像和/或显微镜，（2）针对生物学或医学科学的应用以及（3）分析或计算成分。学生将通过每两周一次的社交活动，参加研究研讨会和专业发展课程，与他们的队列分享经验，并与校园其他REUS的参与者进行互动以扩大他们的网络。夏季成就将在向生物医学工程协会（BMES）年度秋季会议提交摘要中达到最终成就，在秋季，他们将重新获得持续的教育和职业增强机会。