Beyond Drosophila: Comparative transcriptomics of schizophoran flies to resolve a rapid radiation

超越果蝇：精神分裂类果蝇的比较转录组学以解决快速辐射问题

基本信息

批准号：
1257960
负责人：
Brian Wiegmann
金额：
$ 60万
依托单位：
North Carolina State University
依托单位国家：
美国
项目类别：
Continuing Grant
财政年份：
2013
资助国家：
美国
起止时间：
2013-06-15 至 2017-05-31
项目状态：
已结题

来源：
https://www.nsf.gov/awardsearch/showAward?AWD_ID=1257960&HistoricalAwards=false
关键词：
Beyond Drosophila Comparative transcriptomics schizophoran

项目摘要

Large comparative studies of fly genes are currently limited to mosquitoes and the Drosophila (fruit fly) complex. Drosophila belongs to Schizophora, a group of flies with over 50,000 species that includes model organisms, disease vectors, and agricultural pests. Schizophoran phylogenetic relationships are poorly understood because flies diversified very rapidly in the past, leaving few genetic clues to decipher relationships. The investigators will use a new and innovative approach that harnesses the power of transcriptome DNA sequencing to reveal thousands of genetic clues to decipher this rapid radiation of species. This research will generate an ortholog database that will allow other insect researchers to study genes across a wide diversity of insects. The study will advance our understanding of insect evolution by exploring the evolution of a wider range of genes. The researchers will also provide comprehensive training to a PhD student and several undergraduates in modern evolutionary research. Fly biodiversity and evolution-based outreach will be developed and presented through collaboration with Nature Research Center in Raleigh, NC. Results of the study will be used in educational materials to promote research, the understanding of evolution, and species conservation to the public and k-16.

蝇基因的大量比较研究目前仅限于蚊子和果蝇（果蝇）复合物。果蝇属于Schizophora，这是一组苍蝇，其中超过50,000种，其中包括模型生物，疾病媒介和农业害虫。精神分子的系统发育关系被鲜为人知，因为过去的苍蝇非常迅速，几乎没有遗传线索来破译关系。研究人员将使用一种新的创新方法，该方法利用转录组DNA测序的力量揭示了数千个遗传线索，以破译这种快速的物种辐射。这项研究将产生一个直系同源数据库，该数据库将使其他昆虫研究人员能够研究各种昆虫的基因。这项研究将通过探索更广泛的基因的进化来提高我们对昆虫进化的理解。研究人员还将为博士生和现代进化研究中的几名大学生提供全面的培训。通过与北卡罗来纳州罗利自然研究中心的合作，将开发和介绍基于进化的范围和基于进化的外展。该研究的结果将用于教育材料中，以促进研究，对进化的理解以及对公众和K-16的物种保护。