Acquisition of a Mass Spectrometer for a Capillary High Performance Liquid Chromatograph/Mass Spectrometer (LC/MS)

采购用于毛细管高效液相色谱仪/质谱仪 (LC/MS) 的质谱仪

• 批准号: 1125821
• 负责人: Richard Newman
• 金额: $ 13.35万
• 依托单位: Museum of Fine Arts
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-08-15 至 2014-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1125821&HistoricalAwards=false
• 关键词: Acquisition; Mass; Spectrometer; Capillary; Performance

With this award from the Major Research Instrumentation (MRI) Program, Dr. Richard Newman from the Museum of Fine Arts and colleague Richard Laursen (Boston University) will acquire a capillary liquid chromatograph (LC) interfaced with an ion trap-mass spectrometer. The award will enhance research training and education at all levels, especially in areas such as analyses of natural and synthetic dyestuffs used in cultural artifacts (including textiles, easel and wall paintings, and polychromed sculpture). The objectives of this project are to gain insights into the compounds that are found in the raw (plant) source material; to enable comparisons between these compounds and those actually present on test samples that have been dyed or colored with the natural materials using a variety of extraction and dyeing procedures; as well as to provide information to identify the dyestuffs on deteriorated artifacts in which original dye components may have been significantly altered.Mass spectrometers (MS) are used to identify the chemical composition of a sample by measuring the mass of the molecular constituents in the sample after they are ionized and detected. This instrument couples a capillary liquid chromatography system with the mass analysis ability. The liquid chromatograph separates minute volumes of mixtures of compounds extracted from the art pieces into its molecular components. These components then flow into a mass spectrometer where they are ionized and their masses determined. The instrumentation will be used not only for research that will help preserve art but also in laboratory courses at nearby Simmons College.

通过大型研究工具（MRI）计划的奖项，美术博物馆和同事理查德·劳森（Richard Laursen）（波士顿大学）将获得与离子陷阱质谱仪相连的毛细血管液相色谱仪（LC）。该奖项将在各个层面上增强研究培训和教育，尤其是在文化伪像（包括纺织品，画架和壁画以及多色雕塑）的自然和合成染料分析等领域。该项目的目的是洞悉原始（植物）材料中发现的化合物；为了在这些化合物和实际上存在于已使用自然材料染色或使用各种提取和染色程序染色的测试样品上进行比较； 除了提供信息以识别可能已显着改变原始染料成分的恶化伪影的染料。质谱仪（MS）用于通过测量样品中样品中的分子成分的质量来识别样品的化学成分，后它们被静止化并检测到样品。该仪器将毛细管液相色谱系统融合在一起，具有质量分析能力。液态色谱法分离了从艺术品中提取的化合物的分子量，使其分子成分。然后，这些组件流入质谱仪中，在那里它们被电离并确定质量。该仪器将不仅用于有助于维护艺术品的研究，还将用于附近西蒙斯学院的实验室课程。