MRI: Acquisition of a Laser Ablation - Inductively Coupled Plasma - Triple Quadrupole - Mass Spectrometer (LA-ICP-QQQ-MS) System For Research and Education

MRI：获取用于研究和教育的激光烧蚀 - 电感耦合等离子体 - 三重四极杆 - 质谱仪 (LA-ICP-MS/MS) 系统

• 批准号: 2320040
• 负责人: Charles Speer
• 金额: $ 74.44万
• 依托单位: Idaho State University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-08-15 至 2026-07-31
• 项目状态: 未结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2320040&HistoricalAwards=false
• 关键词: MRI; Acquisition; Laser; Ablation; Inductively

This Major Research Instrument award supports the acquisition of an Agilent 8900 Triple Quadrupole – Inductively Coupled Plasma – Mass Spectrometer (ICP-QQQ) coupled with the Coherent ExciStar XS Excimer laser 193nm (LA) with large object chamber (LOC). This LOC-LA-ICP-QQQ next-generation research instrument will open new frontiers of research in archaeology, biological sciences, environmental sciences, forensic anthropology, and geosciences. This project benefits an international group of 28 researchers and 14 cooperating institutions in multidisciplinary groups to conduct unique materials analysis and enable diverse research at Idaho State University (ISU). The instrument will allow chemical analysis of elements ranging from 2–275 atomic mass unit. This instrument will serve as a research and teaching system for all faculty, students, researchers, and staff at ISU. This instrument will be operated and cared for by the Center for Archaeology, Materials, and Spectroscopy Idaho and the Department of Anthropology in the College of Arts and Letters. The instrument will be open to all researchers across campus for grant funded and student research projects. This shared instrument will serve to increase faculty and student scholarship, attract outside researchers, and promote collaboration. It will attract and retain diverse and exceptional faculty and students, enhance teaching and learning, and foster community support. The availability of this shared instrument gives the ISU community the opportunity to explore research questions that are not currently possible in the region. This is especially true for the substantial proportion of female, rural, Indigenous, Hispanic, and low-income students at ISU that often look for employment outside of academia. The LA-ICP-QQQ instrument will be used to recruit minority students to our graduate programs who can conduct original research under mentorship of the co-PI group. We will train and engage students in understanding how they can apply sophisticated techniques to answer challenging questions about the past and today in both the natural and social sciences, as well as to help plan for improved futures in our region.The acquisition of this instrument is a significant improvement in the analytical capabilities of ISU. The Excimer laser is unparalleled in its capability with high-precision, non-destructive and rapid analysis, reduced contamination, and depth profiling. All of this when coupled with the LOC allows for the most accurate analysis for challenging samples across disciplines. The Agilent 8900 is a multi-tool mass spectrometer allows the research groups to conduct an array of analyses for liquids, solids, and gases. It introduces analytical capabilities such as low-level determination of previously difficult elements, separation of direct isobaric overlaps, and fast, trace analysis of emerging nano-scale materials to extend the application of ICP-MS into new frontiers of analysis. Several examples of these projects are: investigation of numerous human behaviors including technological development, decision making, and mobility worldwide through the tracing of stone tools to their geologic sources; conduct numerous geochronology analyses, determine U-Pb crystallization/cooling ages of rocks, Lu- Hf data, assess profiles of soil chemistry at archaeological sites, reveal changes in volcanic sediment composition through time, and fingerprint trace element geochemical signatures in various rocks and minerals in river systems; help solve numerous forensics missing persons cases, including those of unidentified migrants, by applying new trace element analytical techniques; examine how interactions among biological, geological, and chemical systems impact human health via groundwater consumption and contamination; and investigate the pivotal role that heavy metals play in the virulence of bacteria, particularly among invertebrate hosts.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

该重大研究仪器奖项支持购买 Agilent 8900 三重四极杆 - 电感耦合等离子体 - 质谱仪 (ICP-MS/MS) 以及配备大型物室 (LOC) 的相干 ExciStar XS 准分子激光器 193 nm (LA)。 -ICP-MS/MS下一代研究仪器将开辟考古学、生物科学、环境科学、该项目有利于爱达荷州立大学 (ISU) 的 28 名研究人员和 14 个合作机构组成的国际小组进行独特的材料分析并实现多样化的研究。该仪器将允许对 2 种元素进行化学分析。 –275 原子质量单位。该仪器将作为 ISU 所有教师、学生、研究人员和工作人员的研究和教学系统。该仪器将由考古、材料和研究中心操作和维护。爱达荷州光谱学和艺术与文学学院的人类学系将向全校所有研究人员开放资助项目和学生研究项目。该共享仪器将有助于增加教师和学生的奖学金，吸引外部研究人员。它将吸引和留住多样化和优秀的教师和学生，加强教学和促进社区支持，该共享工具的可用性使 ISU 社区有机会探索该地区目前无法实现的研究问题。对于相当大比例的女性来说尤其如此， ISU 经常在学术界以外寻找工作的农村、土著、西班牙裔和低收入学生 LA-ICP-MS/MS 将用于招募少数民族学生加入我们的研究生课程，他们可以在公司的指导下进行原创性研究。 -PI 小组。我们将培训学生并让他们了解如何应用复杂的技术来回答自然科学和社会科学领域过去和今天的挑战性问题，并帮助规划改善我们地区的未来。收购该仪器的显着改进是ISU 的分析能力无与伦比，具有高精度、无损、快速分析、减少污染和深度剖析的能力，所有这些与 LOC 结合使用时，可以对各种具有挑战性的样品进行最准确的分析。 Agilent 8900 是一款多功能质谱仪，研究小组可以对液体、固体和气体进行一系列分析，例如低浓度测定。这些项目的几个例子包括：对许多人类行为（包括技术）的研究。通过追踪石器的地质来源，进行大量地质年代学分析，确定岩石的 U-Pb 结晶/冷却年龄、Lu-Hf 数据，评估考古遗址的土壤化学概况，揭示世界范围内的开发、决策和流动性；的变化随时间变化的火山沉积物成分，以及河流系统中各种岩石和矿物的微量元素地球化学特征，通过应用新的微量元素分析技术，帮助解决许多法医失踪案件，包括身份不明的移民案件； ，以及化学系统通过地下水消耗和污染影响人类健康；并调查重金属在细菌毒力中发挥的关键作用，特别是在无脊椎动物宿主中。该奖项反映了 NSF 的法定使命，并被认为是值得的。通过使用基金会的智力优势和更广泛的影响审查标准进行评估来提供支持。