Acquisition of a 500 MHz NMR Spectrometer

购买 500 MHz NMR 波谱仪

• 批准号: 0821508
• 负责人: Krishna Kumar
• 金额: $ 34.95万
• 依托单位: Tufts University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-08-01 至 2011-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0821508&HistoricalAwards=false
• 关键词: Acquisition; 500; MHz; NMR; Spectrometer

With this award from the Major Research Instrumentation program (MRI), Krishna Kumar and colleagues David L. Kaplan, David H. Lee, Elena V. Rybak-Akimova and David R. Walt from Tufts University will acquire a two channel 500 MHz NMR spectrometer with pulsed field gradients for use by multiple investigators spanning three departments and two schools on the Medford campus of the University. The NMR spectrometer will enable research by a diverse group of researchers in the chemical and biological sciences ranging from characterization of organometallic/protein complexes and cellulose polymers, to the analysis of non-natural fluorinated peptides and post-translational modifications of proteins that direct supramolecular self-assembly.Nuclear Magnetic Resonance (NMR) spectroscopy is one of the most powerful tools available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectrometers is essential to chemists who are carrying out frontier research. The results from these NMR studies will have an impact in synthetic organic/inorganic chemistry and biochemistry.

凭借重大研究仪器计划 (MRI) 授予的这一奖项，塔夫茨大学的 Krishna Kumar 及其同事 David L. Kaplan、David H. Lee、Elena V. Rybak-Akimova 和 David R. Walt 将购买一台两通道 500 MHz NMR 波谱仪具有脉冲场梯度，可供大学梅德福校区三个系和两所学校的多名研究人员使用。 核磁共振波谱仪将使化学和生物科学领域的不同研究人员能够进行研究，范围从有机金属/蛋白质复合物和纤维素聚合物的表征，到非天然氟化肽的分析和指导超分子自身的蛋白质翻译后修饰-组装。核磁共振 (NMR) 光谱是化学家阐明分子结构的最强大工具之一。它用于识别未知物质，表征分子内原子的特定排列，并研究溶液中分子之间相互作用的动力学。对于进行前沿研究的化学家来说，使用最先进的核磁共振波谱仪至关重要。这些核磁共振研究的结果将对合成有机/无机化学和生物化学产生影响。