Synthetic and Mechanistic Studies on the Homogeneous Catalysis of Transition Metal Complexes

过渡金属配合物的均相催化合成及机理研究

• 批准号: 9710504
• 负责人: Iwao Ojima
• 金额: $ 40.5万
• 依托单位: SUNY at Stony Brook
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-07-01 至 2000-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9710504&HistoricalAwards=false
• 关键词: Synthetic; Mechanistic; Studies; Homogeneous; Catalysis

Stony Brook This research has two foci. First, the development of new carbocyclization reactions will be carried out by probing cascade tricyclizations, by trapping of the intermediates in silylcarbocyclization (SiCaC) reactions and by testing the scope of hetero-SiCaC reactions. Second, a synthetic and mechanistic study of homogeneous catalysis in supercritical carbon dioxide will be carried out. Both higher reaction rates and greater reaction selectivity are to be expected from this approach. With this renewal award, the Synthetic Organic Program and the Office of Multidiciplinary Activities are supporting the research of Dr. Iwao Ojima of the Department of Chemistry at the State University of New York, Stony Brook. Professor Ojima will focus his work on developing new and efficient homogeneous catalytic reactions incorporating carbocyclizations and carbonylations in conjunction with heterobimetallic catalyst systems. The methodology affords synthetic chemists powerful tools for the preparation of a large number of cyclic molecules.

Stony Brook这项研究有两个焦点。 首先，将通过探测级联反应的发展，通过捕获级别的三环体作用，通过捕获中间体在甲硅烷基钙化反应（SICAC）反应中以及测试异质 - 西卡克反应的范围。 其次，将对超临界二氧化碳中均质催化的合成和机械研究进行。从这种方法中可以预期较高的反应速率和更高的反应选择性。 通过此续签奖，合成有机计划和多学科活动办公室正在支持纽约州立大学斯托尼·布鲁克（Stony Brook）化学系的Iwao Ojima博士的研究。 Ojima教授将重点放在开发新的，有效的均质催化反应上，结合了碳细胞和羰基化，并结合了异质金属催化剂系统。 该方法为合成化学家提供了准备大量环状分子的强大工具。