The Evolutionary Role of Epistasis for Fitness in Chamacrista Fasciculata

Chamacrista Fasciculata 上位性对健康的进化作用

• 批准号: 9312067
• 负责人: Charles Fenster
• 金额: $ 24.27万
• 依托单位: University of Maryland, College Park
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1993
• 资助国家: 美国
• 起止时间: 1993-10-15 至 1998-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9312067&HistoricalAwards=false
• 关键词: Evolutionary; Role; Epistasis; Fitness; Chamacrista

9312067 Fenster The central theme of the proposed research concerns determining the type of gene action which is responsible for genetic differences among populations of the common native legume, Partridge Pea. Genes may act independently of one another so that genetic divergence may simply reflect the accumulated effects of artificial or natural selection acting on single genes. However, it is just as likely that important differences among organisms may reflect selection on combinations of genes. Selection acting on combination of genes means that gene interaction or epistasis is important. The type of gene action can be determined by following the survivorship and reproduction of progeny derived from crosses between parents that are separated from one another by increasing distance.%%% Results from this project using Partridge Pea as a model system may have important implications for a number of different disciplines including evolution, crop and animal breeding, and conservation biology. If organisms are adapted to their environment because of interactions among genes, then our models of evolution will need to be more complex. In addition where gene interactions occur different breeding strategies than those presently employed may have greater efficacy for crop and animal improvement. Strategies for maintaining or preserving genetic diversity in endangered species will also be influenced by whether gene interaction determines traits associated with survivorship, reproduction, or yield.***

9312067 Fenster提出的研究的中心主题涉及确定基因作用的类型，该基因作用的类型是导致普通本地豆类豆类Partridge Pea种群中遗传差异的遗传差异。 基因可以彼此独立起作用，以便遗传差异可以简单地反映出作用于单个基因的人工选择或自然选择的累积作用。 但是，生物体之间的重要差异可能反映了基因组合的选择。 作用于基因组合的选择意味着基因相互作用或上毒很重要。 基因作用的类型可以通过遵循从父母之间的杂交中获得的生存和繁殖来确定，这些后代通过增加距离而彼此分离。%%％使用Partridge Pea作为模型系统与该项目的结果可能对许多不同的学科具有重要意义，包括多种不同的学科，包括进化，农作物和动物育种和保护生物学。 如果由于基因之间的相互作用而适应了生物体，那么我们的进化模型将需要变得更加复杂。 此外，基因相互作用与目前使用的育种策略不同的繁殖策略可能对作物和动物的改善具有更大的功效。 濒危物种中维持或保存遗传多样性的策略也将受到基因相互作用是否决定与生存，繁殖或产量相关的特征。***