Salivary Steriod Correlates of Successful Conception

唾液类固醇与成功受孕的相关性

• 批准号: 9118074
• 负责人: Peter Ellison
• 金额: $ 20.86万
• 依托单位: Harvard University
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1992
• 资助国家: 美国
• 起止时间: 1992-03-01 至 1996-02-29
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9118074&HistoricalAwards=false
• 关键词: Salivary; Steriod; Correlates; Successful; Conception

The primary objective of this research is to study normal variation in human ovarian function. This will be undertaken through the measurement of steroid hormones in healthy women living in the Cambridge Massachusetts area over a time course. The primary, longitudinal data will consist of progesterone and estradiol levels, determined from salivary samples, for each female over an extended time course. A variety of steroid profiles are expected to emerge and hazards-model analysis will be used to relate these to various life events. This research will make it possible to assess the impact of normal variability in ovarian function on female fecundity and increase our understanding of human reproductive ecology.

这项研究的主要目的是研究人类卵巢功能的正常变异。 这将通过在马萨诸塞州剑桥市的健康女性中测量类固醇激素来进行。 在延长的时间过程中，纵向数据将由孕激素和雌二醇水平由唾液样本确定。 预计会出现多种类固醇特征，并将使用危害模型分析将这些分析与各种生活事件联系起来。 这项研究将使评估正常变异性对卵巢功能对女性繁殖力的影响成为可能，并增强我们对人类生殖生态学的理解。